B O O K - American College of Rheumatology

ACR/ARHP Poster Session B
1182. Allogeneic Mesenchymal Stem Cells Inhibited OAZ Expression
in Patients with Systemic Lupus Erythematosus. Xuebing Feng 1 ,
Rongliang Li 2 , Jing Huang 2 , Dandan Wang 2 , Xiaolei Ma 2 , Betty
P. Tsao 3 and Lingyun Sun 2 , 1 Affiliated Drum Tower Hospital of
Nanjing University Medical School, Nanjing, China, 2 Affiliated
Drum Tower Hospital of Nanjing University Medical School,
3
UCLA School of Medicine, Los Angeles, CA.
1183. Analysis of Vascular Endothelium from Female Systemic Lupus
Erythematosus (SLE) Patients Identifies an Interferon Signature
That Correlates with Disease Activity. Diana Goldenberg 3 ,
Mikhail Olferiev 3 , Duygu Onat 1 , Danieli Andrade 3 , Mary K. Crow 3 ,
Paolo C. Colombo 1 and Jane E. Salmon 2 , 1 Columbia University
College of Physicians and Surgeons, New York, NY, 2 Hospital for
Special Surgery, New York, NY, 3 Hospital for Special Surgery, New
York, NY.
1184. Anti-C1q Antibodies Are Associated with Global Activity of
Systemic Lupus Erythematosus, but Not Specifically with
Nephritis. Yuko Okamoto 1 , Yasuhiro Katsumata 5 , Yasushi
Kawaguchi 2 , Kohei Miyake 5 , Manabu Kawamoto 5 , Kae Takagi 5 ,
Takahisa Gono 5 , Sayumi Baba 5 , Yuko Ota 5 , Masako Hara 4 and
Hisashi Yamanaka 3 , 1 Tokyo Women’s Medical University, Tokyo,
Japan, 2 Tokyo Women’s Medical University, Tokyo, Japan, 3 Tokyo
Women’s Medical University, Shinjuku-ku, Tokyo, Japan, 4 Tokyo
Women’s Medical University, Kamakura Kanagawa, Japan,
5
Tokyo Women’s Medical University.
1185. Biomarkers of Oxidative Stress, mTOR Activation, and Treg
Depletion Correlate with Disease Activity in Patients with
Systemic Lupus Erythematosus. Zhiwei Lai 1 , Adam Bartos 1 ,
Tiffany Tekarico 1 , Robert Hanczko 1 , Gabriella Miklossy 1 , Brandon
Clair 1 , John Jimah 1 , Lisa Francis 1 , Hajra Tily 1 , Ricardo Garcia 1 ,
Maha Dawood 1 , David R. Fernandez 1 , Paul E. Phillips 2 , Ioana
Coman 1 and Andras Perl 3 , 1 SUNY, 2 SUNY-Upstate Medical Univ,
Syracuse, NY, 3 Upstate Medical Univ, Syracuse, NY.
1186. CD138 RNA Can Be Detected in the Circulation of Patients with
Systemic Lupus and Correlated to Other Factors Suggestive of
Plasma Cell Activation. Ming Chen 3 , Joy G. Hutcheson 2 , Stan
Kamp 2 , Danny Walker 2 and Joan T. Merrill 1 , 1 Oklahoma Med
Research Foundation, Oklahoma City, OK, 2 OMRF, Oklahoma
City, OK, 3 OMRF, Allen, TX.
1187. Characterisation of Lipid Order in Lymphocyte Subsets from
Patients with Systemic Lupus Erythematosus (SLE). Laura
Miguel 2 , Chrissie Lim 2 , David A. Isenberg 1 and Elizabeth C. Jury 2 ,
1
UCL Div of Medicine, London, United Kingdom, 2 University
College London, London, United Kingdom.
1188. Correlates of ANA Positivity in Healthy Individuals. David R.
Karp 2 , Quan-Zhen Li 2 , Valerie K. Branch 2 , Jiexia Quan 3 and Nancy
J. Olsen 1 , 1 Univ of TX Southwestern Med Ctr, Dallas, TX, 2 UT
Southwestern Med Ctr, Dallas, TX, 3 UT Southwestern Med Ctr.,
Dallas, TX.
1189. Dysfunctional, Pro-Inflammatory High Density Lipoproteins
Directly Influence Monocyte PDGFRβ Transcript Levels,
TNFα Secretion, and Chemotaxis. Brian J. Skaggs 1 , Bevra H.
Hahn 4 , Lori Sahakian 2 , Jennifer M. Grossman 3 and Maureen
A. McMahon 1 , 1 UCLA School of Medicine, Los Angeles, CA,
2
UCLA School of Medicine, 3 University of California Los Angeles,
Sherman Oaks, CA, 4 University of California Los Angeles School
of Medicine, Los Angeles, CA.
1190. Dysregulation of the Microvascular as Assessed by Expression
of Protective and Injury Associated Markers Is Reflected in
the Non-Lesional Non-Sunexposed Skin of Patients with Lupus
Nephritis. Peter M. Izmirly 1 , Shane Meehan 2 , Sherry X. Xu 2 ,
Anca D. Askanase 1 , Joan T. Merrill 3 , Jill P. Buyon 1 and Robert M.
Clancy 4 , 1 NYU School of Medicine, New York, NY, 2 NYU School
of Medicine, 3 Oklahoma Med Research Foundation, Oklahoma
City, OK, 4 Tisch Hospital 4-407, New York, NY.
1191. Evidence of N-methyl-D-aspartate Receptor (NMDAR)
Expression on Primary Human Endothelial Cells. Cagri Yildirim-
Toruner 3 , Paola Mina-Osario 2 and Betty Diamond 1 , 1 Feinstein
Institute for Medical Research, Manhasset, NY, 2 Feinstein
Institute for Medical Research, 3 Morgan Stanley Children’s
Hospital of NewYork- Presbyterian Columbia University Medical
Center, Feinstein Institute for Medical Research, New York, NY.
1192. Expession of B Cell Subsets in SLE Pregnancy: Correlation
with Preterm Birth. Megan E. B. Clowse 1 , Sara Sparks 2 , Sallie
Allgood 2 , Mark Lanasa 2 and David S. Pisetsky 3 , 1 Duke Univ Med,
Durham, NC, 2 Duke University, Durham, NC, 3 Duke University
Medical Ctr, Durham, NC.
1193. Increased Male Fetal Loss and Fewer Male Siblings in a Cohort
of Systemic Lupus Erythematosus Families. Rachna Aggarwal 1
and Robert H. Scofield 2 , 1 OUHSC, 2 OUHSC, OMRF, VA.
1194. Low Levels of Atheroprotective Natural IgM Antibodies Against
Phosphorylcholine and Increased Prevalence of Vulnerable
Atherosclerotic Plaques in Patients with SLE. Cristina Anania 2 ,
Thomas Gustafsson 2 , Xiang Hua 2 , Jun Su 2 , Mikael Heimbürger 1 ,
Tomas Jogestrand 2 and Johan Frostegård 2 , 1 Abbot, 2 Karolinska
Institutet.
1195. Presence of HMGB1 (High Mobility Group Box 1) and
Antibodies to HMGB1 in Systemic Lupus Erythematosus (SLE).
Deena Abdulahad, Johanna Westra, Pieter Limburg, Cees
Kallenberg and Marc Bijl, UMCG.
1196. Reversal of CD3+/CD4+/CD25+/Foxp3+ Treg Depletion in
Active SLE Patients with Rapamycin. Zhiwei Lai 1 , Tiffany N.
Telarico 1 , Adam Bartos 1 , Gabriella Miklossy 1 , Robert Hanczko 1 ,
John Jimah 1 , Brandon Clair 1 , Lisa Francis 1 , Hajra Tily 1 , Ricardo
Garcia 1 , Paul E. Phillips 2 , Irene Ramos 1 and Andras Perl 3 , 1 SUNY,
2
SUNY-Upstate Medical Univ, Syracuse, NY, 3 Upstate Medical
Univ, Syracuse, NY.
1197. Strong Viral Associations among Filipinos with Systemic Lupus
Erythematosus. Evan Glenn Vista 6 , Michael H. Weisman 3 ,
Mariko L. Ishimori 1 , Jourdan Anderson 5 , Robelle Tanangunan 8 ,
Noga Gal 2 , John B. Harley 7 , Guthridge Joel 5 , Sandra Navarra 8
and Judith A. James 4 , 1 Cedars Sinai Medical Center, Los Angeles,
CA, 2 Cedars-Sinai, 3 Cedars-Sinai Medical Center, Los Angeles,
CA, 4 Oklahoma Med Research Foundation, Oklahoma City, OK,
5
Oklahoma Medical Research Foundation, 6 Oklahoma Medical
Research Foundation, Oklahoma City, OK, 7 Univ of OK Hlth Sci
Ctr, Oklahoma City, OK, 8 University of Santo Tomas Hospital.
1198. TNFα Expression in Peripheral Blood Mononuclear Cells
of Cutaneous Lupus & Dermatomyositis Patients. Adam S.
Nabatian 2 , Maria Wysocka 4 , Muhammad M. Bashir 1 and Victoria
P. Werth 3 , 1 Philadelphia VAMC, University of Pennsylvania,
2
UMDNJ-Robert Wood Johnson Medical School, Philadelphia
VAMC, University of Pennsylvania, 3 University of Pennsylvania,
Philadelphia, PA, 4 University of Pennsylvania.
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2010 Program Book