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B O O K - American College of Rheumatology

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ACR/ARHP Poster Session C<br />

1780. Towards a Data-Driven Evaluation <strong>of</strong> the 2010 ACR/EULAR<br />

Criteria for Rheumatoid Arthritis: Is It Sensible To Look at<br />

Levels <strong>of</strong> Rheumatoid Factor? M. P. M. van der Linden 4 , M.<br />

R. Batstra 1 , L. E. Bakker-Jonges 1 , J. Detert 2 , H. Bastian 2 , H. U.<br />

Scherer 2 , G. R. Burmester 2 , M. D. Mjaavatten 3 , T. K. Kvien 3 , R. E.<br />

M. Toes 4 , T. W. J. Huizinga 4 and A. H. M. van der Helm-van Mil 4 ,<br />

1<br />

Department <strong>of</strong> Medical Laboratories, Reinier de Graaf Group,<br />

Delft, The Netherlands, on Behalf <strong>of</strong> SKML-HIM (WGHAS),<br />

2<br />

Department <strong>of</strong> <strong>Rheumatology</strong> and Clinical Immunology, Charité<br />

University Medicine Berlin, Berlin, Germany, 3 Department<br />

<strong>of</strong> <strong>Rheumatology</strong>, Diakonhjemmet Hospital, Oslo, Norway,<br />

4<br />

Department <strong>of</strong> <strong>Rheumatology</strong>, Leiden University Medical<br />

Center, Leiden, The Netherlands.<br />

1781. Ultrasound Evaluation Reveals the Reason for High Interrater<br />

Variability in Joints <strong>of</strong> the 66/68 Joint Count. Matthias<br />

Nikolaus Witt 2 , Monika Ronneberger 1 , Amelie Schnez 3 , Ruediger<br />

Laubender 4 , Matthias Engelbrecht 1 , Arthur Kavanaugh 6 , Hendrik<br />

Schulze-Koops 5 and Mathias Grunke 3 , 1 Department <strong>of</strong> Internal<br />

Medicine 3 , University <strong>of</strong> Erlangen-Nuremberg, Erlangen,<br />

Germany, 2 Division <strong>of</strong> <strong>Rheumatology</strong>, Ludwig-Maximilians-<br />

University, Munich, Germany, 3 Division <strong>of</strong> <strong>Rheumatology</strong>,<br />

Ludwig-Maximilians-University, Munich, Germany, 4 Institute <strong>of</strong><br />

Medical Informatics, Biometry and Epidemiology (IBE), Ludwig-<br />

Maximilians-University, Munich, Germany, 5 Ludwig-Maximilians-<br />

University, Munich, Germany, 6 University <strong>of</strong> California-San<br />

Diego, La Jolla, CA.<br />

1782. Validation <strong>of</strong> a Multi-Biomarker Test for Rheumatoid Arthritis<br />

(RA) Disease Activity (Vectra DA) in a Multi-Cohort Study.<br />

Jeffrey R. Curtis 9 , Doug Haney 3 , Annette H. M. van der Helm 5 ,<br />

Yijing Shen 3 , Rachel Knevel 5 , Guy Cavet 3 , Linda Dirven 5 ,<br />

Cornelia F. Allaart 4 , Thomas W. J. Huizinga 5 , Michael Centola 6 ,<br />

Lyndal K. Hesterberg 3 , David Chern<strong>of</strong>f 3 , John Carulli 1 , Nancy<br />

A. Shadick 2 , Michael E. Weinblatt 2 , Max I. Hamburger 8 , Roy<br />

M. Fleischmann 7 and Ed C. Keystone 10 , 1 Biogen Idec, 2 Brigham<br />

&Womens Hospital, Boston, MA, 3 Crescendo Bioscience, Inc.,<br />

4<br />

Leiden Univ Med Ctr, Leiden, The Netherlands, 5 Leiden Univ<br />

Med Ctr, 6 Oklahoma Med Research Foundation, Oklahoma<br />

City, OK, 7 <strong>Rheumatology</strong> Associates, Dallas, TX, 8 <strong>Rheumatology</strong><br />

Associates <strong>of</strong> LI, Dix Hills, NY, 9 University <strong>of</strong> Alabama -<br />

Brimingham, Birmingham, AL, 10 University <strong>of</strong> Toronto, Toronto,<br />

ON, Canada.<br />

1783. Validation <strong>of</strong> New Classification Criteria for Rheumatoid<br />

Arthritis in Japanese Population. Hisanori Shimizu 1 , Hiromichi<br />

Tamaki 3 , Eishi Uechi 3 , Mitsumasa Kishimoto 2 , Ken-ichi<br />

Yamaguchi 3 and Masato Okada 1 , 1 St. Luke’s International<br />

Hospital, Tokyo, Japan, 2 St. Luke’s International Hospital, Chuoku,<br />

Tokyo, Japan, 3 St. Luke’s International Hospital.<br />

1784. Validity <strong>of</strong> Clinical Associations <strong>of</strong> Biomarkers in Translational<br />

Research Studies: The Case <strong>of</strong> Systemic Autoimmune Diseases.<br />

Maria Tektonidou 2 and Michael Ward 1 , 1 National Institute <strong>of</strong><br />

Arthritis and Musculoskeletal and Skin Diseases, 2 National<br />

University <strong>of</strong> Athens.<br />

1785. Validity <strong>of</strong> the Revised ACR/EULAR Classification Criteria for<br />

Rheumatoid Arthritis: Predicting Persistent Arthritis and Joint<br />

Erosions after 2 Years in Patients with Early Undifferentiated<br />

Arthritis. Jaap Fransen 3 , Mieke Hazes 2 and Henk Visser 1 , 1 Alysis<br />

Hospital, Arnhem, The Netherlands, 2 Erasmus Medical Centre,<br />

Rotterdam, The Netherlands, 3 Radboud University Nijmegen<br />

Medical Centre, Nijmegen, The Netherlands.<br />

1786. Vitamin D Levels Do Not Correlate with Disease Activity,<br />

Erosions, or Inflammatory Markers in Patients with Active<br />

Rheumatoid Arthritis. Joshua Baker 2 , Daniel G. Baker 1 , Gary<br />

Toedter, Justine Shults and Mary B. Leonard, 1 Centocor Inc,<br />

Malvern, PA, 2 University <strong>of</strong> Pennsylvania, Philadelphia, PA.<br />

1787. Work Disability in Early Rheumatoid Arthritis: Prognostic<br />

Factors after Two Years <strong>of</strong> Follow-Up. Fausto Salaffi 1 ,<br />

Gianfranco Ferraccioli 3 , Marina Carotti 2 , Alessandro Ciapetti 1 ,<br />

Stefania Gasparini 1 and Walter Grassi 1 , 1 Department <strong>of</strong><br />

Molecular Pathology and Innovative Therapies, Division<br />

<strong>of</strong> <strong>Rheumatology</strong>, University <strong>of</strong> Ancona (Politecnica delle<br />

Marche), Italy, 2 Department <strong>of</strong> Radiology, University <strong>of</strong> Ancona<br />

(Politecnica delle Marche), Italy, 3 School <strong>of</strong> Medicine, Catholic<br />

University <strong>of</strong> the Sacred Heart, Rome, Italy.<br />

Rheumatoid Arthritis Treatment - Small Molecules, Biologics and<br />

Gene Therapy: Biologic DMARDs III<br />

1788. A Study To Evaluate the Effectiveness and Safety <strong>of</strong> the<br />

Interleukin-6 (IL-6) Receptor Antagonist Tocilizumab (TCZ) after<br />

4 and 24 Weeks in Patients with Active Rheumatoid Arthritis<br />

(RA) – Final Effectiveness Results <strong>of</strong> the TAMARA Study. Eugen<br />

Feist 1 , Andrea Rubbert-Roth 2 , Jürgen Braun 6 , Jörg Kaufmann 4 ,<br />

Herbert L. Kellner 7 , Reiner Kurthen 3 , Jürgen Wollenhaupt 5 and<br />

Gerd R. Burmester 1 , 1 Campus Charité Mitte, Med. Klinik Abt.<br />

Rheumatologie u. Klin. Immunologie, Berlin, Germany, 2 Klinik I<br />

für Innere Medizin, Uniklinik Cologne, Cologne, Germany, 3 Praxis<br />

für Innere Medizin und Rheumatologie, Aachen, Germany,<br />

4<br />

Praxis für Innere Medizin und Rheumatologie, Ludwigsfelde,<br />

Germany, 5 Rheumatologikum Hamburg, Schön-Klinik Hamburg-<br />

Eilbeck, Hamburg, Germany, 6 Rheumazentrum Ruhrgebiet, St.<br />

Josefs-Krankenhaus, Herne, Germany, 7 Schwerpunktpraxis fuer<br />

Rheumatologie und Gastroenterologie, Munich, Germany.<br />

1789. Age at Onset and Comorbidities Correlate with the Health<br />

Assessment Questionnaire and Clinical Disease Activity Index<br />

(CDAI) Responses to Etanercept in Rheumatoid Arthritis<br />

Patients. Man R. Shim 6 , Harold E. Paulus 1 , Sandeep Chaudhari 3 ,<br />

JingYaun Feng 2 , David A. Elash<strong>of</strong>f 4 and Veena K. Ranganath 5 ,<br />

1<br />

Encino, CA, 2 Amgen, 3 Kforce Clinical Research/Amgen, 4 UCLA,<br />

5<br />

UCLA School <strong>of</strong> Med Rehab 32-59, Los Angeles, CA, 6 UCLA/ VA<br />

Greater Los Angeles Healthcare System, Los Angeles, CA.<br />

1790. Assessment <strong>of</strong> Real Life Efficacy <strong>of</strong> Rituximab in Rheumatoid<br />

Arthritis: Predicting Factors <strong>of</strong> the Therapeutic Maintenance<br />

and Demonstration <strong>of</strong> a Corticosteroid Sparing Effect in<br />

the AutoImmunity and Rituximab Registry. Jacques-Eric<br />

Gottenberg 10 , Philippe Ravaud 4 , Thomas Bardin 6 , Patrice<br />

Cacoub 5 , Alain Cantagrel 11 , Bernard Combe 8 , Maxime<br />

Dougados 2 , René-Marc Flipo 7 , Bertrand Godeau 3 , Loic Guillevin 2 ,<br />

Eric Hachulla 7 , Xavier Le Loët 9 , Thierry Schaeverbeke 1 , Jean<br />

Sibilia 10 , Gabriel Baron 4 and Xavier Mariette, 1 Bordeaux<br />

Hospital, 2 Cochin Hospital, 3 Henri Mondor Hospital, 4 Hotel Dieu<br />

Hospital, 5 La Pitié Hospital, 6 Lariboisière Hospital, 7 Lille Hospital,<br />

8<br />

Montpellier Hospital, 9 Rouen Hospital, 10 Strasbourg Hospital,<br />

11<br />

Toulouse Hospital.<br />

1791. Clinical and Functional Improvements in Early RA Following<br />

Treatment with Adalimumab Plus Methotrexate Compared<br />

with Methotrexate Monotherapy: 26-Week Results <strong>of</strong> the<br />

OPTIMA Trial. Arthur Kavanaugh 5 , Roy Fleischmann 6 , Paul<br />

Emery 3 , Benoit Guérette 1 , Laura Redden 2 , Kaushik Patra 2 and<br />

Josef S. Smolen 4 , 1 Abbott Laboratories, Rungis, France, 2 Abbott<br />

Laboratories, Abbott Park, IL, 3 Leeds Teaching Hospital, Leeds,<br />

United Kingdom, 4 Medical University <strong>of</strong> Vienna and Hietzing<br />

Hospital, Vienna, Austria, 5 University <strong>of</strong> California San Diego,<br />

La Jolla, CA, 6 University <strong>of</strong> Texas Southwestern Medical Center,<br />

Dallas, TX.<br />

2010 Program Book 257

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