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B O O K - American College of Rheumatology

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and insufficiency<br />

• recall sources <strong>of</strong> controversy regarding the optimal vitamin D<br />

level for bone health<br />

• recall vitamin D assay variability and the challenges this<br />

provides in diagnosing deficiency<br />

• prescribe standard and alternative treatments for vitamin D<br />

deficiency<br />

ACR Clinical Symposium<br />

1:00 - 2:00 pm<br />

Thomas J. Murphy Ballroom<br />

Clinical Review: Immunizations and Rheumatic<br />

Diseases - An Update c/r cP PS<br />

Moderators: Zsuzsanna H. McMahan, MD; Johns Hopkins<br />

University; Baltimore, MD<br />

Arthur Kavanaugh, MD; University <strong>of</strong> California-San Diego; La<br />

Jolla, CA<br />

Speaker: Clifton O. Bingham, MD; Johns Hopkins University;<br />

Baltimore, MD<br />

Session Overview:<br />

This review is designed to provide an update on safety and<br />

efficacy issues as they relate to the immunization <strong>of</strong> patients<br />

with rheumatic disease. The diversity <strong>of</strong> the available<br />

treatments for rheumatic disease, as well as the increase in<br />

the recommended immunizations for adults, makes it critical<br />

to provide regular updates for clinicians. Rheumatologists are<br />

frequently required to render an opinion about the safety and<br />

efficacy <strong>of</strong> immunizations for their patients. The goals <strong>of</strong> this<br />

clinical review are to provide clinicians with updates on the<br />

effects <strong>of</strong> rheumatic drugs/biologics on vaccinations; evidence<br />

for efficacy <strong>of</strong> immunizations in rheumatic diseases; and safety<br />

<strong>of</strong> immunizations for patients with rheumatic diseases.<br />

in the physiological regulation <strong>of</strong> endogenous glucocorticoids<br />

and in understanding the cellular and molecular mechanisms <strong>of</strong><br />

glucocorticoid action.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• describe the physiological mechanisms <strong>of</strong> glucocorticoid<br />

regulation<br />

• explain cellular and molecular mechanisms <strong>of</strong> glucocorticoid<br />

action<br />

• identify pharmacological approaches for optimizing the clinical<br />

efficacy <strong>of</strong> glucocorticoids in reducing potential adverse side<br />

effects in inflammatory and musculoskeletal conditions<br />

B406<br />

Genetic Disorders <strong>of</strong> Connective Tissue and Joint<br />

Hypermobility R<br />

Moderator: Rodney Grahame, MD; University <strong>College</strong> Hospital;<br />

London, United Kingdom<br />

Speaker: Peter H. Byers, MD; University <strong>of</strong> Washington; Seattle,<br />

WA<br />

Session Overview:<br />

Genetic alterations in connective tissue matrix proteins result<br />

in a number <strong>of</strong> conditions seen by both pediatric and adult<br />

rheumatologists. These conditions include Marfan’s and<br />

various types <strong>of</strong> Ehler-Danlo’s syndrome that result in joint<br />

hypermobility and contribute to the development <strong>of</strong> arthritis.<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• define the common genetic disorders in connective tissue<br />

proteins<br />

• describe the contribution <strong>of</strong> genetic disorders in connective<br />

tissue proteins to joint disorders<br />

• analyze how mutations in connective tissue proteins can result<br />

in joint hypermobility<br />

monday<br />

Upon completion <strong>of</strong> this session, participants should be able to:<br />

• identify the efficacy and safety issues related to immunizations<br />

in adults with rheumatic diseases<br />

• examine the impact <strong>of</strong> specific rheumatic treatments on the<br />

efficacy <strong>of</strong> vaccinations<br />

• review the latest recommendations and guidelines for the<br />

immunization <strong>of</strong> adults<br />

ACR State-<strong>of</strong>-the-Art Lectures<br />

1:00 - 2:00 pm<br />

B313<br />

2010 Hench Lecture: Glucocorticoids-Physiologic<br />

Regulation, Mechanisms <strong>of</strong> Action and Optimizing<br />

Therapeutic Applications c/r<br />

Moderator: Steven R. Goldring, MD; Hospital for Special Surgery;<br />

New York, NY<br />

Speaker: George P. Chrousos, MD; Athens University<br />

Medical School; Patras, Greece<br />

Session Overview:<br />

Glucocorticoids have diverse and complex effects on the<br />

function and activity <strong>of</strong> multiple cells types and tissues. There<br />

have been major advances in dissecting mechanisms involved<br />

ACR REF Special Session<br />

1:00 - 2:00 pm<br />

A311<br />

ACR REF Memorial Lectureship: <strong>Rheumatology</strong><br />

Education 2010 Ed.<br />

The 2010 REF Memorial Lectureship is in honor <strong>of</strong> Walter Barr,<br />

MD.<br />

Moderator: David I. Daikh, MD, PhD; University <strong>of</strong> California, San<br />

Francisco, Veterans Affairs Medical Center; San Francisco, CA<br />

Speaker: Dennis W. Boulware, MD; Kaiser Permanente<br />

Medical Center; Honolulu, HI<br />

Session Overview:<br />

Many rheumatologists are currently unaware <strong>of</strong> the impact <strong>of</strong><br />

the Residency Review Committee on the field <strong>of</strong> rheumatology<br />

and how recent changes in the program requirements<br />

for rheumatology are impacting the new generation <strong>of</strong><br />

rheumatologists. This session will increase the awareness <strong>of</strong><br />

the issues relevant to rheumatology currently being addressed<br />

by the Residency Review Committee, the importance <strong>of</strong><br />

competency-based education and issues that the Accreditation<br />

Council for Graduate Medical Education is addressing for all<br />

graduate medical education.<br />

2010 Program Book 37

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