B O O K - American College of Rheumatology

5
University of Twente and Medisch Spectrum Twente, Enschede,
The Netherlands, 6 Ziekenhuisgroep Twente, Almelo/Hengelo,
The Netherlands
3:45 PM
663. The Association of Joint Damage and Treatment Response
with ACPA Status in Recent Onset RA.
M. van den Broek 3 , N. B. Klarenbeek 4 , M. L. Westedt 1 , H.
D. Boom 5 , P. J. S. M Kerstens 2 , T. W. J. Huizinga 4 , B. A. C.
Dijkmans 6 and C. F. Allaart 4 , 1 Bronovo Hospital, The Hague, The
Netherlands, 2 JBI, Amsterdam, The Netherlands, 3 LUMC, Leiden,
The Netherlands, 4 LUMC, Leiden, The Netherlands, 5 Spaarne
Hospital, Hoofddorp, The Netherlands, 6 VU Medical Centre,
Amsterdam, The Netherlands
B402
Spondylarthropathies and Psoriatic Arthritis - Clinical
Aspects and Treatment - Imaging I
Moderators: Desiree M. Van Der Heijde, MD, PhD; Leiden
University Medical Center; Meerssen, The Netherlands
Juergen Braun, MD; Rheumazentrum Ruhrgebiet; Herne,
Germany
2:30 PM
664. Methotrexate Is Not Disease Modifying in Psoriatic
Arthritis: The MIPA Trial.
Gabrielle H. Kingsley 3 , Anna Kowalczyk 4 , Helen Taylor 4 , Fowzia
Ibrahim 4 , Jonathan C. Packham 2 , Neil J. McHugh 7 , Diarmuid M.
Mulherin 1 , George D. Kitas8, Kuntal Chakravarty 6 , Brian D. M.
Tom 5 , Peter J. Maddison 9 and David L. Scott 4 , 1 Cannock Chase
Hospital, Cannock, United Kingdom, 2 Haywood Hospital, Stoke
on Trent, UK, 3 Kings College London, London, United Kingdom,
4
Kings College London, UK, 5 MRC Biostatistics Unit, University
of Cambridge, UK, 6 Queens Hospital, Romford, UK, 7 Royal
National Hospital for Rheumatic Diseases, Bath, UK, 8 Russells
Hall Hospital, Dudley, UK, 9 Sport, Health and Exercise Science,
University of Bangor, UK
2:45 PM
665. Rates and Predictors of Radiographic Sacroiliitis
Progression over Two Years in Patients with Axial
Spondyloarthritis.
Denis Poddubnyy 1 , Martin Rudwaleit 1 , Hildrun Haibel 1 , Anja
Weiss 3 , Elisabeth Märker-Hermann 4 , Henning Zeidler 5 , Jürgen
Braun 6 and Joachim Sieper 2 , 1 Charité - Campus Benjamin
Franklin, Berlin, Germany, 2 Charite Campus Benjamin Frankl,
Berlin, Germany, 3 Deutsches Rheumaforschungszentrum,
Berlin, Germany, 4 Dr. Horst Schmidt Kliniken, Wiesbaden,
Germany, 5 Medizinische Hochschule, Hannover, Germany,
6Rheumazentrum Ruhrgebiet, Herne, Germany
3:00 PM
666. High Prevalence of Axial Spondyloarthritis in Patients with
Familial Mediteranean Fever, and a Greater Allelic Frequency
of M694V in Familial Mediteranean Fever Patients with
Radiograpic Sacroiliitis.
Servet Akar 2 , Ozgul Soysal 2 , Feride Yuksel 1 , Dilek Solmaz 2 , Gercek
Can 2 , Merih Birlik 2 , Mehmet Tunca 1 , Fatos Onen 2 and Nurullah
Akkoc 2 , 1 Internal Medicine, Dokuz Eylul University Faculty of
Medicine, Izmir, Turkey, 2 Rheumatology, Dokuz Eylul University
Faculty of Medicine, Izmir, Turkey
3:15 PM
667. Evidence That New Focal Fat Lesions Follow Resolution of
Spinal Inflammation in AS but Existing Lesions Are More Likely
To Resolve with TNF Blocking Agents.
Praveena Chiowchanwisawakit 1 , Robert G. W. Lambert 2 and
Walter P. Maksymowych 2 , 1 Mahidol University, Bangkok,
Thailand, 2 University of Alberta, Edmonton, AB, Canada
3:30 PM
668. New Bone Formation in the Spine of Patients with
Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Ankylosing
Spondylitis (AS) – A Detailed Comparative Analysis of the Rates
of Radiographic Progression over 6 Years.
Xenofon Baraliakos 3 , Joachim Listing 1 , Jana Buschmann 3 , Anna
von der Recke 3 and Juergen Braun 2 , 1 German Rheumatism
Research Center, 2 Rheumazentrum Ruhrgebiet, Herne, Germany,
3
Rheumazentrum Ruhrgebiet Herne
3:45 PM
669. Relationship between Active Inflammatory Lesions
in the Spine and Sacroiliac Joints and New Development
of Fatty Infiltration on Whole-Body MRI in Early Axial
Spondyloarthritis– Results of the ESTHER Trial at Week 48.
In-Ho Song 1 , Kay-Geert Hermann 2 , Hildrun Haibel 1 , Christian
Althoff 2 , Joachim Listing 3 , Bruce Freundlich 4 , Martin
Rudwaleit 1 and Joachim Sieper 1 , 1 Charite Campus Benjamin-
Franklin, Medical Clinic I, Rheumatology, Berlin, Germany,
2
Charite Campus Mitte, Radiology, Berlin, Germany, 3 German
Rheumatism Research Center, Berlin, Germany, 4 Wyeth/ Pfizer
Inc., Collegeville, PA
A311
Systemic Sclerosis, Fibrosing Syndromes, and
Raynaud’s - Pathogenesis, Animal Models and Genetics
Moderators: David Abraham, PhD, BSc; University College
London; London, United Kingdom
Robert A. Lafyatis, MD; Boston University School of Medicine;
Arlington, MA
2:30 PM
670. Growth Differentiation Factor-9 Induced by Insulin-Like
Growth Factor Binding Protein-5 May Contribute to Fibrosis in
Systemic Sclerosis.
Yukie Yamaguchi 2 and Carol A. Feghali-Bostwick 1 , 1 University of
Pittsburgh, Pittsburgh, PA, 2 University of Pittsburgh, Yokohama
City University, Yokohama, Kanagawa, Japan
2:45 PM
671. Epithelial Cells Undergoing Epithelial Mesenchymal
Transition (EMT) in Systemic Sclerosis Lack Caveolin-1 and
Modulate WNT Signaling in the Dermis by Secreting SFRP4.
Ilaria Tinazzi, Justin Gillespie, Giuseppina Abignano, Chiara
Colato, Domenico Biasi, Paul Emery and Francesco Del Galdo,
University of Leeds
3:00 PM
672. The Notch Pathway Controls Fibroblast Activation and
Tissue Fibrosis in Systemic Sclerosis.
Clara Dees 2 , Pawel Zerr 2 , Michal Tomcik 2 , Christian Beyer 2 ,
Angelika Horn 2 , Alfiya Akhmetshina 2 , Katrin Palumbo 2 , Nicole
Reich 2 , Jochen Zwerina 2 , Mark P. Mattson 3 , Oliver Distler 1 ,
Georg Schett 2 and Joerg H. W. Distler 2 , 1 Center of Experimental
Rheumatology and Zurich Center of Integrative Human
monday
2010 Program Book 43