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NIS - libdoc.who.int - World Health Organization

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Folium cum Flore Crataegi<br />

pr o c y a n i d i n 2 2 ' 3 3 ' 4<br />

B 1 α -( R ) α -( R ) α -( R ) β -( S) β -( R )<br />

B 2 α -( R ) α -( R ) α -( R ) α- ( R ) β -( R )<br />

B 3 α -( R ) α -( R ) β -( S) β -( S) α -( S)<br />

B 4 α -( R ) α -( R ) β -( S) α- ( R) α -( S)<br />

Medicinal uses<br />

Uses supported by clinical data<br />

Treatment of chronic congestive heart failure stage II, as defined by the<br />

New York Heart Association (24–34).<br />

Uses described in pharmacopoeias and in traditional systems<br />

of medicine<br />

Support of cardiac and circulatory functions (35).<br />

Uses described in folk medicine, not supported by experimental<br />

or clinical data<br />

As an antispasmodic agent in the treatment of asthma, diarrhoea, gall<br />

bladder disease and uterine contractions, and as a sedative for the treatment<br />

of insomnia (5).<br />

Pharmacology<br />

Experimental pharmacology<br />

Inotropic effects<br />

Positive inotropic effects of Folium cum Flore Crataegi and its constituents<br />

have been demonstrated both in vitro and in vivo. These effects are<br />

97

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