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Radix Althaeae
Weak inhibition (17%) of mucociliary transport in isolated, ciliated
epithelium of the frog oesophagus was demonstrated after treatment of
the isolated tissues with 200 µl of an aqueous root macerate (6.4 g/140 ml)
(29).
Antitussive activity
Intragastric administration of a polysaccharide fraction, isolated from an
aqueous root extract, to cats (50 mg/kg body weight) suppressed the intensity
and the frequency of coughs induced by mechanical irritation of
laryngopharyngeal and tracheobronchial mucosa (30). The antitussive activity
of this polysaccharide fraction (50 mg/kg body weight) was as effective
as Syrupus Althaeae (1.0 g/kg body weight), and more effective
than prenoxdiazine (30 mg/kg body weight) (30).
Clinical pharmacology
None.
Contraindications
No information available.
Warnings
No information available.
Precautions
Drug interactions
Simultaneous administration of Radix Althaeae may delay the absorption
of other drugs (8).
Other precautions
No information available on general precautions or precautions concerning
drug and laboratory test interactions; carcinogenesis, mutagenesis,
impairment of fertility; teratogenic and non-teratogenic effects in pregnancy;
nursing mothers; or paediatric use. Therefore, Radix Althaeae
should not be administered during pregnancy or lactation or to children
without medical supervision.
Adverse reactions
No information available.
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