NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
Other precautions
No information available on general precautions or precautions concerning
drug interactions; drug and laboratory test interactions; or carcinogenesis,
mutagenesis and impairment of fertility.
Adverse reactions
Clinical studies have shown that extracts of Radix Urticae are well tolerated
in humans. A few cases of minor transient gastrointestinal sideeffects,
such as diarrhoea, gastric pain and nausea (32, 35), and allergic
skin reactions (32), have been reported.
Dosage forms
Crude drug for infusion; hydroalcoholic extracts (4, 56). Store in a wellclosed
container, protected from light and humidity (2, 13).
Posology
(Unless otherwise indicated)
Daily dosage: 4–6 g crude drug or equivalent preparations as an infusion
(4, 56); 600–1200 mg dried 20% methanol extract (5:1) (22, 25, 27, 31, 32);
1.5–7.5 ml 45% ethanol extract (1:1) (29); 5 ml 40% ethanol extract (1:5)
(17, 23).
References
1. British herbal pharmacopoeia. London, British Herbal Medicine Association,
1996.
2. Deutsches Arzneibuch. Stuttgart, Deutscher Apotheker Verlag, 1998.
3. Bombardelli E, Morazzoni P. Urtica dioica L. Fitoterapia, 1997, 68:387–402.
4. Blaschek W et al., eds. Hagers Handbuch der pharmazeutischen Praxis. Folgeband
2: Drogen A-K, 5th ed. Berlin, Springer-Verlag, 1998.
5. Farnsworth NR, ed. NAPRALERT database. Chicago, University of Illinois
at Chicago, IL, February 9, 1998 production (an online database available
directly through the University of Illinois at Chicago or through the
Scientific and Technical Network [STN] of Chemical Abstracts Services).
6. Patten G. Urtica. Australian Journal of Medical Herbalism, 1993, 5:5–13.
7. Bisset NG. Herbal drugs and phytopharmaceuticals. Boca Raton, FL, CRC
Press, 1994.
8. Grieve M. A modern herbal. Vol. II. New York, NY, Dover Publications,
1981.
9. Bedevian AK. Illustrated polyglottic dictionary of plant names in Latin, Arabic,
Armenian, English, French, German, Italian and Turkish languages. Cairo,
Argus & Papazian Press, 1936.
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