NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
and tree pollens were negative. The results of patch tests with Tilia flowers
with a standard series and a series of plant allergens were positive. A bronchial
challenge test was performed in an inhalation chamber for 30 minutes.
In the first stage, the patient was challenged with placebo (potato flour);
during the second stage (after 7 days), with depilatory wax that had been
thermally activated, and after 14 days with dried flowers. Following such
exposures, clinical symptoms of rhinoconjunctivitis appeared, and were
observed for 48 hours after the challenges. In addition, increases in eosinophil
and basophil proportions in nasal lavage and tear fluids were observed
during the late phase of allergic reaction. A diagnosis of occupational allergy
was made based on the positive results of the allergy tests, analysis of
the clinical status and medical history, and the positive results of specific
challenges (64).
Over a 5-year period, 1790 paediatric outpatients were observed for suspected
allergic symptoms and 371 children were given a skin prick test to
check for responses to aeroallergens. Aeroallergen sensitization due to Tilia
cordata was observed in 11.4% of the paediatric patients examined (65).
Contraindications
If signs of hypersensitivity reaction appear (contact dermatitis or rhinoconjunctivitis),
Flos Tiliae must not be used again.
Warnings
No information was found.
Precautions
General
No information was found.
Drug interactions
No information was found.
Drug and laboratory test interactions
No information was found.
Carcinogenesis, mutagenesis, impairment of fertility
No information was found.
Pregnancy: teratogenic effects
No information was found.
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