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NIS - libdoc.who.int - World Health Organization

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WHO monographs on medicinal plants commonly used in the Newly Independent States (<strong>NIS</strong>)<br />

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sion also indicates its use for the supportive treatment of dyspeptic symptoms<br />

and gastro<strong>int</strong>estinal catarrh (5).<br />

Uses described in traditional medicine<br />

Traditionally S. officinalis has been used to treat hoarseness and coughs<br />

(54, 55). It is also used as a sedative, tonic, and stimulant (56). Salvia officinalis<br />

has a long history of use as a restorative of lost or declining cognitive<br />

functions in Western European systems of traditional medicine (57).<br />

Salvia officinalis leaves are also used for treatment of haemorrhages, hyperhydrosis,<br />

galactorrhoea and dysentery (58–60). In traditional Italian<br />

medicine, they are used to treat rheumatism (61, 62). The use of S. officinalis<br />

for the treatment of menstrual disorders has been reported (63, 64).<br />

It is also used to treat acne, hair loss and dandruff, as a vulnerary and an<br />

antiseptic (65, 66).<br />

Pharmacology<br />

Experimental pharmacology<br />

Antioxidant activity<br />

A 95% ethanol and an aqueous-ethanol (1:1) extract of dried leaves of S. officinalis<br />

demonstrated antioxidant activity in vitro at concentrations of<br />

0.01% and 0.025%, respectively, against 2,2´-azobis(2-amidinopropane)<br />

dihydrochloride-induced liposome peroxidation (67, 68). A fat-soluble ex-<br />

348

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