NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
patients with exudative pleuritis. Thus, the diuretic effect seems to be
greatest in patients with cardiovascular diseases (48).
Adverse reactions
Allergic reactions including contact dermatitis and urticaria have been
documented for the styles and stigmas of Zea mays (36).
Contraindications
Styli cum stigmatis Zeae maydis is contraindicated in patients with loss of
appetite and a low body mass or, in view of the ability of this drug to decrease
clotting time, those with high coagulability of blood (76, 80). It is
not recommended for irrigation therapy (hydro-colon therapy) in patients
with oedema due to impaired heart or kidney function (70). If signs
of hypersensitivity reactions appear (contact dermatitis and urticaria) the
styles and/or stigmas of Zea mays must not be used again.
Warnings
No information was found.
Precautions
General
Prolonged use may result in hypokalaemia because of the diuretic action (36).
Drug interactions
No information was found.
Drug and laboratory test interactions
No information was found.
Carcinogenesis, mutagenesis, impairment of fertility
No information was found on carcinogenesis or impairment of fertility. A
mutagenic effect has been reported for an ethanol extract (see Toxicology).
Pregnancy: teratogenic effects
No information was found.
Pregnancy: non-teratogenic effects
Styles and/or stigmas of Zea mays have been reported to stimulate uterine
contractions in rabbits. Styles and/or stigmas should therefore not be
taken during pregnancy without consultation with a physician (36).
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