02.10.2014 Views

NIS - libdoc.who.int - World Health Organization

NIS - libdoc.who.int - World Health Organization

NIS - libdoc.who.int - World Health Organization

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

Radix Ginseng<br />

Antidiabetic activity<br />

Radix Ginseng has been shown in clinical studies to have beneficial effects<br />

in both insulin-dependent and non-insulin-dependent diabetic patients<br />

(86, 87). Oral administration of ginseng tablets (200 mg daily for 8 weeks)<br />

to 36 non-insulin-dependent patients elevated mood, improved physical<br />

performance, reduced fasting blood glucose and serum aminoterminal<br />

propeptide of type III procollagen concentrations, and lowered glycated<br />

haemoglobin (87).<br />

Impotence<br />

Ginseng extracts improved sperm production in men and may have some<br />

usefulness in treating impotence (32). The ginsenosides, which appear to<br />

be the active components, are thought to depress blood prolactin levels,<br />

thereby increasing libido (32). In one clinical study, 90 patients with erectile<br />

dysfunction were treated with ginseng saponins (600 mg orally per<br />

day). Treatment improved rigidity, tumescence, and libido, but not the<br />

frequency of coitus (88).<br />

Contraindications<br />

None (21, 50, 89, 90).<br />

Warnings<br />

No information available.<br />

Precautions<br />

General<br />

Diabetic patients should consult a physician prior to taking Radix Ginseng,<br />

as ginseng <strong>int</strong>ake may slightly reduce blood glucose levels (86, 87).<br />

Drug <strong>int</strong>eractions<br />

There are two reports of an <strong>int</strong>eraction between Radix Ginseng and phenelzine,<br />

a monoamine oxidase inhibitor (91, 92). The clinical significance of<br />

this <strong>int</strong>eraction has not been evaluated.<br />

Drug and laboratory test <strong>int</strong>eractions<br />

None reported.<br />

Carcinogenesis, mutagenesis, impairment of fertility<br />

Radix Ginseng is not carcinogenic or mutagenic in vitro, and does not<br />

have any effect on fertility (90).<br />

151

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!