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NIS - libdoc.who.int - World Health Organization

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WHO monographs on medicinal plants commonly used in the Newly Independent States (<strong>NIS</strong>)<br />

to lanceolate (sometimes with two small lobes at the base), round or<br />

wedge-shaped base, round or subacute apex, crenulate margins, finely<br />

wrinkled by a strongly-marked network of veins on both sides, upper<br />

and lower surfaces greyish-green, softly hairy and glandular, 2–10 cm<br />

long, 0.8–1.5(–4)cm wide. Inflorescences, loose spikes of flower <strong>who</strong>rls.<br />

Flowers, bisexual, zygomorphic, 2 cm long, bluish-violet or purplish,<br />

sometimes white. Bracts, sessile, ovate-lanceolate, acuminate, membranous,<br />

and striated at the base. Peduncles, curly-pubescent, 3–6 mm long.<br />

Calyx, campanulate, membranous, striated, downy (especially outside<br />

on the veins and the margins of the sepals), bilabiate; the upper lip<br />

3-toothed; the lower bifid; all the teeth subulate and acuminate, 9–10 mm<br />

long. Corolla, 2 or 3 times as long as the calyx, with a large projecting<br />

tube, ringed on the inside, and bilabiate; upper lip arched, lower lip trilobed,<br />

the lateral lobes being reflexed. Pistil, single, superior 4-lobed<br />

ovary. The two usually absent upper stamens are sometimes present in<br />

very small-sterile hooks. Fruit, 4 nutlets, nearly round, brown, 2.5 mm in<br />

diameter (5, 8, 17, 18, 21–26).<br />

Plant material of <strong>int</strong>erest: dried leaves<br />

Fresh material may also be used, provided that when dried it complies<br />

with the monograph in the European Pharmacopoeia (27).<br />

General appearance<br />

The lamina of <strong>who</strong>le leaf is about 2–10 cm long and up to 3 cm wide,<br />

oval, oblong-ovate, elliptical to lanceolate; upper surface pubescent,<br />

lower surface tomentose, texture soft and velvety. The margin is finely<br />

crenulate to smooth. The apex is rounded or subacute and the base is<br />

shrunken at the petiole and rounded or cordate. Both surfaces with conspicuous,<br />

reticulate venation. The deeply depressed venation on the upper<br />

surface is very prominent on the lower surface and shows a dense<br />

network of raised veinlets. The upper surface is pale green and finely<br />

granular; the lower surface is greyish-green to white and pubescent. Petiole<br />

up to about 4 cm. The cut drug consists of small leaf fragments,<br />

which, because of the dense tomentum, cling together; the fine pubescence<br />

on both surfaces and the reticulate venation on the lower surface<br />

are easily recognized (1, 5, 28, 29).<br />

Organoleptic properties<br />

Odour: <strong>int</strong>ensely spicy and aromatic; taste: spicy, aromatic, bitter and<br />

slightly astringent (2, 5).<br />

344

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