NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
Hypotensive activity
Intravenous injection of ethanol, aqueous and ether extracts of dried
whole plant to dogs and rats at doses of 50 mg/kg and 500 mg/kg bw, respectively,
produced a hypotensive effect (44).
Cytotoxic activity
A 10% aqueous extract of the dried flowers of the plant was inactive
against HeLa cells in cell culture (43).
Clinical pharmacology
No information was found.
Adverse reactions
No information was found.
Contraindications
Due to the bile-stimulating effect of the drug, it should not be administered
when there is obstruction of the bile ducts due to gallstones. It
should only be used in patients with gallstones after consultation with a
physician (30, 45).
Precautions
General
Increased health risks or adverse effects following the correct administration
of Helichrysum arenarium at therapeutic dosages have not been
recorded, however chronic use may cause development of bile congestion
(46).
Drug interactions
No information was found.
Carcinogenesis, mutagenesis, impairment of fertility
No information was found.
Pregnancy
No information was found.
Nursing mothers
No information was found.
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