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NIS - libdoc.who.int - World Health Organization

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WHO monographs on medicinal plants commonly used in the Newly Independent States (<strong>NIS</strong>)<br />

min. Not more than 35% of bruised fruits if the juice is not lost (1, 2). Not<br />

more than 4% in dried fruits (39).<br />

Total ash<br />

Not more than 1% (1). Not more than 6% in dried fruits (39).<br />

Acid-insoluble ash<br />

No information available on fresh fruits. Not more than 3% in dried<br />

fruits (39).<br />

Sulfated ash<br />

No information available on fresh fruits. Not less than 25% in dried<br />

fruits (39).<br />

Water-soluble extractive<br />

No information available.<br />

Alcohol-soluble extractive<br />

No information available.<br />

Loss on drying<br />

Not more than 87% (1).<br />

Pesticide residues<br />

The recommended maximum sum limit of aldrin and dieldrin is not more<br />

than 0.05 mg/kg (43). For other pesticides, see the European pharmacopoeia<br />

(43) and the WHO guidelines on quality control methods for medicinal<br />

plant materials (41) and pesticide residues (44).<br />

Heavy metals<br />

For maximum limits and analysis of heavy metals, consult the WHO<br />

guidelines on quality control methods for medicinal plant materials (41).<br />

Radioactive residues<br />

Where applicable, consult the WHO guidelines on quality control methods<br />

for medicinal plant materials (41) for the analysis of radioactive isotopes.<br />

Other purity tests<br />

Content of mineral matter not more than 0.5%. Content of acids in the<br />

fruits not more than 3% (1, 2). Chemical, sulfated ash, and water-soluble<br />

190

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