NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
Sulfated ash
No information available.
Water-soluble extractive
No information available.
Alcohol-soluble extractive
No information available.
Loss on drying
Not more than 12% (28). Not more than 10% (24).
Pesticide residues
The recommended maximum limit of aldrin and dieldrin is not more than
0.05 mg/kg (32). For other pesticides, see the European pharmacopoeia
(32) and the WHO guidelines on quality control methods for medicinal
plant materials (31) and pesticide residues (33).
Heavy metals
For maximum limits and analysis of heavy metals, consult the WHO
guidelines on quality control methods for medicinal plant materials (31).
Radioactive residues
Where applicable, consult the WHO guidelines on quality control methods
for medicinal plant materials (31) for the analysis of radioactive isotopes.
Other purity tests
The content of mineral matter is not more than 2% (28). Chemical, acidinsoluble
ash, sulfated ash, alcohol-soluble extractive, and water-soluble
extractive tests to be established in accordance with national requirements.
Chemical assays
Aerial parts contain not less than 1.5% alkaloids (28). A high-performance
liquid chromatography method for the analysis of specific alkaloids in the
seeds has been developed and validated (30).
Major chemical constituents
The major constituents of the dried aerial parts are indole alkaloids which
dominate during and after flowering when harmine and harmaline pre-
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