NIS - libdoc.who.int - World Health Organization

WHO monographs on medicinal plants commonly used in the Newly Independent States (NIS)
Sulfated ash
No information available.
Water-soluble extractive
Not less than 6% (30).
Alcohol-soluble extractive
Not less than 16% (30).
Loss on drying
Not more than 10% (1) or 13% (2). Not more than 15% (30).
Pesticide residues
The recommended maximum sum limit of aldrin and dieldrin is not more
than 0.05 mg/kg (1). For other pesticides, see the European pharmacopoeia
(1) and the WHO guidelines on quality control methods for medicinal
plant materials (31) and pesticide residues (32).
Heavy metals
For maximum limits and analysis of heavy metals, consult the WHO
guidelines on quality control methods for medicinal plant materials (31).
Radioactive residues
Where applicable, consult the WHO guidelines on quality control methods
for medicinal plant materials (31) for the analysis of radioactive isotopes.
Other purity tests
The content of mineral matter not more than 2% (2). Chemical and sulfated
ash tests to be established in accordance with national requirements.
Chemical assays
Contains not less than 0.3% of total flavonoids, expressed as hyperoside
(1) or not less than 0.5% of flavonoids, expressed as avicularin (2).
Major chemical constituents
The major constituents of the aerial parts are flavonoids (0.1–1%, rarely
2.5–3%): derivatives of kaempferol, quercetin and myricetin, especially
avicularin (quercetin-3-O-arabinoside, approximately 0.2%); juglanin
(kaempferol-3-O-arabinoside), hyperoside, quercitrin, rhamnetin-3-O-
332