UC Davis 2008-2010 General Catalog - General Catalog - UC Davis

400 Microbiology
B.S. program is especially well suited for students
who want a professional career in microbiology, or
who wish to pursue graduate education in a biological
science discipline. The choice of a major program
and its suitability for particular career options
should be discussed with a major adviser.
Career Alternatives. A bachelor’s degree in
microbiology is excellent preparation for a career in
biotechnology, pharmacology, agriculture, and the
food industry. It also provides a strong background
for students wishing to continue on to professional
studies in medicine and the other health sciences.
A.B. Major Requirements:
UNITS
Preparatory Subject Matter ............. 42-56
Biological Sciences 2A-2B-2C ................14
Chemistry 2A-2B ..................................10
Chemistry 8A-8B or 118A-118B-
118C .............................................. 6-12
Mathematics 16A-16B, 17A-17B or
21A-21B ............................................ 6-8
Physics 1A-1B or 7A-7B-7C ................ 6-12
Depth Subject Matter ....................... 37-45
Biological Sciences 101, 102, 103........10
Microbiology 102, 102L, 105, 105L,
140....................................................16
Microbiology 162 or Pathology,
Microbiology, and Immunology 128...... 3-4
Three additional courses from Food Science
and Technology 104; Medical Microbiology
115, 116, 130; Microbiology 100, 120,
150, 155L, 160, 170; Molecular and
Cellular Biology 120L; Pathology,
Microbiology, and Immunology 127; Plant
Pathology 120, 130, 148, 150; Soil Science
111; Statistics 100, 102 .................... 8-15
Total Units for the Major................ 79-101
B.S. Major Requirements:
UNITS
Preparatory Subject Matter ............. 59-69
Biological Sciences 2A-2B-2C ................14
Chemistry 2A-2B-2C .............................15
Chemistry 8A-8B or 118A-118B-
118C .............................................. 6-12
Mathematics 16A-16B-16C or 17A-17B-
17C ................................................ 9-12
Physics 7A-7B-7C .................................12
Statistics 13, 32, 100 or 102 ............... 3-4
Depth Subject Matter ....................... 47-51
Biological Sciences 101, 102, 103,
104....................................................13
Molecular and Cellular Biology 120L........ 6
Microbiology 102, 102L, 105, 105L..... 13
Two courses from Microbiology 140, 150,
or 170 .................................................. 6
Microbiology 162 or Pathology,
Microbiology, and Immunology 128...... 3-4
Two courses from Food Science and
Technology 104; Microbiology 120,
140, 150, 155L, 170, Pathology,
Microbiology, and Immunology 127;
Soil Science 111................................. 6-9
Total Units for the Major.............. 106-120
Master Adviser. John C. Meeks in 209 Briggs
Honors and Honors Program. John C. Meeks
Teaching Credential Subject Representative.
John C. Meeks; see the Teaching Credential/M.A.
Program on page 109.
Graduate Study. The Graduate Group in Microbiology
offers programs of study and research leading
to the M.S. and Ph.D. degrees.
Strong preference is given to doctoral applicants.
The group offers study in general microbiology,
microbial physiology, microbial genetics, molecular
mechanisms of microbial regulation, molecular
mechanisms of microbial pathogenesis, immunology,
virology, and recombinant DNA technology. For
information on the graduate study and undergraduate
preparation for the program contact a graduate
adviser or the Chairperson of the Group.
Related Courses. The offerings of the Department
of Microbiology are augmented by courses and faculty
of Evolution and Ecology; Food Science and
Technology; Land, Air, and Water Resources; Medical
Microbiology; Medicine and Epidemiology;
Molecular and Cellular Biology; Pathology, Microbiology,
and Immunology; Plant Biology; Plant Pathology;
Viticulture and Enology.
Faculty of the Department of Microbiology also
teach or participate in the following courses: Biological
Sciences 2A, 101 and 104.
Courses in Microbiology (MIC)
Lower Division Courses
10. Natural History of Infectious Diseases
(3)
Lecture—3 hours.Topics in the natural history of
infectious diseases principally affecting humans.
Introduction to infectious microbial agents, ecology,
epidemiology, and induction of disease. Focus on
diseases of a contemporary nature. For students not
majoring in the biological sciences. Not open for
credit to students who have completed course 102.
GE credit: SciEng.—I. (I.) Manning
91. Introduction to Research (1)
Seminar—1 hour. Prerequisite: Biological Sciences
1A or 2A or consent of instructor. Discussion of faculty
research focusing on the biochemistry, genetics,
and cell biology of microorganisms, along with
ways undergraduates can participate in research
projects of faculty members. May be repeated three
times for credit. (P/NP grading only.)—III. (III.)
98. Directed Group Study (1-5)
Prerequisite: consent of instructor. Primarily for lower
division students. (P/NP grading only.)
99. Special Study for Undergraduates (1-5)
(P/NP grading only.)
Upper Division Courses
100. Chemical and Biological Weapons (3)
Lecture/discussion—3 hours. Prerequisite: upper
division standing. Ancient and modern history of
chemical and biological weapons; mechanism of
action; tactical and strategic uses; riot-control
agents; international legal constraints; disarmament
and nonproliferation; genomics and the future. GE
credit: SciEng or SocSci.—Wheelis
101. Introductory Microbiology (5)
Lecture—4 hours; laboratory—3 hours. Prerequisite:
Biological Sciences 1A, or 2A and Chemistry 2B
(Chemistry 2B may be taken concurrently). Survey of
microorganisms emphasizing their interactions with
humans and diseases. Topics include microscopy,
survey of various microbes, the immune system, food
microbiology, microbial pathogens, and mechanisms
of disease transmission. Designed for students
requiring microbiology for professional schools. Not
open for credit to students who have completed
course 102 or 102L.—II, III. (II, III.) Singer
102. General Microbiology (4)
Lecture—4 hours. Prerequisite: Biological Sciences
1A or 2A, and Chemistry 8B or 118B (may be taken
concurrently). Survey of the biology of microorganisms.
Topics include microbial structure, physiology,
genetics, and evolution; virology; environmental
microbiology; the immune system; and microbial
pathogens and disease transmission. In combination
with course 102L, fulfills the Microbiology requirement
for professional schools. Not open for credit to
students who have completed course 101.—I, II, III.
(I, II, III.)
102L. General Microbiology Laboratory (3)
Lecture/laboratory—7 hours. Prerequisite: course
102 (may be taken concurrently); consent of instructor.
Restrictions on Enrollment: Introduction to principles
and laboratory methods in microbiology.
Designed for students continuing in microbiology or
using microorganisms as tools for the study of genetics
and biochemistry. In combination with course
102, fulfills the microbiology requirement for professional
schools. Due to the heavy demand for this
class, students must fill out a petition in order to be
considered for enrollment. The petition will be available
on the Section of Microbiology Web site. Only
two units of credit allowed to students who have
completed course 101.—I, II, III. (I, II, III.)
105. Microbial Diversity (3)
Lecture—3 hours. Prerequisite: course 102, Biological
Sciences 102; Biological Sciences 103 recommended.
Survey of the major groups of
microorganisms emphasizing diversity of energy
metabolism, morphology, evolution, and natural history.
Survey of the major groups of microorganisms
emphasizing diversity of energy metabolism, morphology,
evolution, and natural history. Students
who completed course 105 in 2005 or earlier
received five units of credits for this lecture/laboratory
course. If these students wish to repeat the class,
they must enroll in both course 105 (lecture) and
course 105L (laboratory) for a total of six units of
credit.—II. (II.) Dawson, Parales
105L. Microbial Diversity Laboratory (3)
Laboratory—9 hours (8 hours scheduled lab periods;
1 hour during open laboratory). Prerequisite:
courses 102, 102L, 105 (may be taken concurrently),
Biological Sciences 102; Biological
Sciences103 recommended. Isolation and characterization
of microbial strains from various habitats.
Includes methods for determination of evolutionary
relationships among groups. Due to the heavy
demand for this class, students must fill out a petition
in order to be considered for enrollment. The petition
will be available on the Section of Microbiology
Web site. Not open for credit to students who completed
course 105 in 2005 or earlier.—II. (II.) Dawson,
Nelson, Parales
115. Recombinant DNA Cloning and
Analysis (3)
Lecture—3 hours. Prerequisite: Biological Sciences
101 or equivalent. Cloning and analysis of recombinant
DNA, with emphasis on Escherichia coli hostvector
systems. DNA-modifying enzymes; vectors
and their use; manipulation and expression of insert
DNA; polymerase chain reaction; and sequence
annotation. Graduate students see course 215. Not
offered every year.
120. Microbial Ecology (3)
Lecture—3 hours. Prerequisite: course 105, Biological
Sciences 102 or 105. Interactions between nonpathogenic
microorganisms and their environment,
emphasizing physiological and metabolic characteristics
of various groups and their adaptation to and
modification of specific habitats.—III. (III.) Nelson
140. Bacterial Physiology (3)
Lecture—3 hours. Prerequisite: Biological Sciences
101, 102, 103 (103 may be taken concurrently), or
Biological Sciences 101, 105; Microbiology 102
recommended. Fundamentals of bacterial growth
and bacterial responses to environmental stresses.
Topics will include carbon and nitrogen regulation,
growth rate control, post-exponential growth, and
motility and chemotaxis. Not open for credit to students
who have completed course 130A.—I. (I.)
Meeks, Singer
150. Bacterial Genetics (3)
Lecture—3 hours. Prerequisite: Biological Sciences
101; 102 or 105; Microbiology 102 recommended.
Molecular genetics of enterobacteria and
their viruses. Isolation of mutants; genetic exchange
and mapping; complementation; suppression; transposons;
gene expression and regulation; and
genomics. Examples will illustrate applications to
molecular cloning of recombinant DNA, and to the
study of bacterial pathogenesis.—II. (II.) Stewart
155L. Bacterial Physiology Lab (4)
Lecture/discussion—1 hour; laboratory—8 hours.
Prerequisite: course 140 or 150, 102L, consent of
instructor. Physiology and genetics of bacteria. Isolation
and characterization of mutant strains. Mapping
of mutations by conjugation and transduction studies
of control of enzyme synthesis by induction, repression,
and catabolite repression.—III. (III.) Singer
162. General Virology (4)
Lecture—4 hours. Prerequisite: Biological Sciences
102 or 105. Integrated presentation of the nature of
animal, bacterial, and plant viruses, including their
Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2009-2010 offering in parentheses
General Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience