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UC Davis 2008-2010 General Catalog - General Catalog - UC Davis

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Microbiology (A Graduate Group) 401<br />

structure, replication and genetics. Only three units<br />

to students who have completed Pathology, Microbiology,<br />

and Immunology 128.—II. (II.) Falk, Manning<br />

170. Yeast Molecular Genetics (3)<br />

Lecture—3 hours. Prerequisite: Biological Sciences<br />

101; 102 or 105; Microbiology 102 or 140<br />

strongly recommended. Survey of the genetics, cell<br />

biology and technologies in yeasts and related<br />

lower eukaryotes. Topics include diversity of yeasts;<br />

cell structure; metabolism; cell cycle; genetic<br />

approaches and genomics; gene expression; yeasts<br />

as models to study higher eukaryotes; and contemporary<br />

techniques.—III. (III.) Shiozaki<br />

170. Yeast Molecular Genetics (3)<br />

Lecture—3 hours. Prerequisite: Biological Sciences<br />

101 and 102; course 102 or 140 (may be take concurrently)<br />

strongly recommended. Survey of the<br />

genetics, cell biology and technologies in yeasts and<br />

related lower eukaryotes. Topics include diversity of<br />

yeasts; cell structure; metabolism; cell cycle; genetic<br />

approaches and genomics; gene expression; yeasts<br />

as models to study higher eukaryotes; and contemporary<br />

techniques.—III. (III.) Shiozaki<br />

190C. Undergraduate Research Conference<br />

(1)<br />

Discussion—1 hour. Prerequisite: upper division<br />

standing and consent of instructor, course 199 concurrently.<br />

Presentation and critical discussion of staff<br />

research activities: designed for advanced undergraduate<br />

students. May be repeated for credit. (P/<br />

NP grading only.)—I, II, III. (I, II, III.)<br />

191. Introduction to Research for Advanced<br />

Undergraduates (1)<br />

Seminar—1 hour. Prerequisite: Biological Sciences<br />

1A or 2A or consent of instructor. Discussion of faculty<br />

research focusing on the biochemistry, genetics,<br />

and cell biology of microorganisms, along with<br />

ways undergraduates can participate in research<br />

projects of faculty members. May be repeated three<br />

times for credit. (P/NP grading only.)—III. (III.)<br />

192. Internship (1-12)<br />

Internship—3-36 hours. Technical and/or professional<br />

experience on or off campus. Supervised by a<br />

member of the Microbiology Section faculty. (P/NP<br />

grading only.)<br />

194H. Microbiology Honors Research (2)<br />

Independent study—6 hours. Prerequisite: senior<br />

standing; eligibility for college honors; completion of<br />

six units of 199 in microbiology; consent of section.<br />

Continuation of an individual microbiological<br />

research project culminating in writing of a senior<br />

thesis under a faculty director. (P/NP grading only.)<br />

197T. Tutoring in Microbiology (1-12)<br />

Prerequisite: upper division standing and consent of<br />

instructor. Assisting the instructor in one of the section’s<br />

regular courses by tutoring individual or small<br />

groups of students in a laboratory, in voluntary discussion<br />

groups, or other voluntary course activities.<br />

May be repeated for credit. (P/NP grading only.)—<br />

I, II, III. (I, II, III.)<br />

198. Directed Group Study (1-5)<br />

Prerequisite: consent of instructor. (P/NP grading<br />

only.)<br />

199. Special Study for Advanced<br />

Undergraduates (1-5)<br />

Prerequisite: consent of instructor. (P/NP grading<br />

only.)<br />

Graduate Courses<br />

200A. Biology of Prokaryotes (3)<br />

Lecture—3 hours. Prerequisite: course 102 or the<br />

equivalent. Intended for first year graduate students<br />

in microbiology and closely related fields. Overview<br />

of prokaryotic biology, with emphasis on phylogeny,<br />

physiology, and diversity of bacteria.—I. (I.)<br />

200B. Advanced Bacteriology (3)<br />

Lecture—3 hours. Prerequisite: course 200A.<br />

Intended for first year graduate students in microbiology<br />

and closely related fields. Advanced topics in<br />

phylogeny, physiology, and diversity of bacteria.<br />

Not offered every year.—II. (II.)<br />

201L. Advanced Microbiology Laboratory<br />

Rotations (5)<br />

Laboratory—15 hours. Prerequisite: course 200A<br />

(may be taken concurrently). Two five-week assignments<br />

in microbiology research laboratories. Individual<br />

research problems with emphasis on<br />

methodological/procedural experience and experimental<br />

design. May be repeated twice for credit.—I,<br />

II. (I, II.)<br />

210. Molecular Mechanisms in Microbial<br />

Pathogenesis (3)<br />

Lecture—3 hours. Prerequisite: course 105 or Veterinary<br />

Microbiology 127 and course 162 or Veterinary<br />

Microbiology 128 or the equivalent. Study of<br />

the molecular mechanisms involved in cytopathogenesis<br />

of higher eukaryotic organisms. Emphasis on the<br />

alteration or inhibition of cellular metabolism and<br />

function by bacteria and animal viruses. Not offered<br />

every year.<br />

215. Recombinant DNA (3)<br />

Lecture—3 hours. Prerequisite: Biological Sciences<br />

101, 102, 103 or the equivalent. Application of<br />

recombinant DNA technology to modern problems<br />

in biology, biochemistry, and genetics, emphasizing<br />

molecular cloning strategies, choice of vectors, preparation<br />

of insert DNA, and selection procedures.—I.<br />

(I.) Privalsky<br />

250. Biology of Yeasts (5)<br />

Lecture—3 hours; discussion—2 hours. Prerequisite:<br />

Biological Sciences 102, 103; course 102, 102L;<br />

course 215 recommended. Survey of the genetics,<br />

physiology, metabolism, regulatory mechanisms,<br />

structure, cell biology, ecology and diversity of<br />

yeasts and related organisms. Not offered every<br />

year.<br />

260. Bacterial Genetic Regulatory<br />

Mechanisms (3)<br />

Lecture/discussion—3 hours. Prerequisite: general<br />

knowledge of nucleic acid biochemistry and bacterial<br />

genetics. Analysis at the molecular level of<br />

genetic regulation in selected bacterial systems. Specific<br />

systems discussed will include the following<br />

types of regulation: control of transcription initiation<br />

and termination; translational controls; tRNA modification<br />

effects; autoregulation; control circuits in bacterial<br />

viruses; supercontrols. Not offered every year.<br />

262. Advanced <strong>General</strong> and Molecular<br />

Virology (3)<br />

Lecture—3 hours. Prerequisite: graduate standing.<br />

Advanced integrated presentation of animal, bacterial,<br />

and plant viruses, including their structure,<br />

modes of regulation, expression and replication,<br />

and effects on host cells and organisms.—II. Bruening<br />

263. Principles of Protein–Nucleic Acid<br />

Interactions (3)<br />

Lecture—3 hours. Prerequisite: advanced graduate<br />

standing and completion of one year of basic graduate<br />

course work in biochemistry, biophysics, chemistry,<br />

genetics, microbiology, or molecular biology.<br />

Physical basis of protein–nucleic acid interaction.<br />

Topics include nucleic acid recognition by proteins,<br />

thermodynamics of protein–nucleic acid stability,<br />

and kinetics of binding process for both non-specific<br />

and sequence-specific nucleic acid binding proteins.<br />

Emphasis on systems that represent paradigms in<br />

protein–nucleic acid interactions. Not offered every<br />

year.<br />

274. Seminar in Genetic Recombination (1)<br />

Seminar—1 hour. Prerequisite: graduate standing;<br />

consent of instructor. Biochemical and genetic<br />

aspects of genetic recombination in prokaryotes and<br />

eukaryotes. Mechanisms of recombination and biochemical<br />

and genetic characteristics of recombination<br />

proteins. Proteins include DNA strand<br />

exchange, DNA helicases, and Holliday junction<br />

resolving proteins. May be repeated for credit. Not<br />

offered every year. (S/U grading only.)<br />

275. Seminar in DNA Repair and<br />

Recombination (1)<br />

Seminar—1 hour. Prerequisite: consent of instructor;<br />

graduate standing in Microbiology or closely related<br />

field. Review and discussion of current research and<br />

literature in DNA repair and recombination with presentations<br />

by individual students and invited speakers.<br />

May be repeated for credit. (S/U grading<br />

only.)—I, II, III. (I, II, III.) Heyer<br />

276. Advanced Concepts in DNA<br />

Metabolism (3)<br />

Lecture—3 hours. Prerequisite: Molecular and Cellular<br />

Biology 221C or Genetics 201C or equivalent<br />

course recommended. DNA damage checkpoints,<br />

homologous recombination, and meiotic recombination.<br />

An advanced treatment of the clinical and current<br />

literature to discuss emerging principles and<br />

current models in these research areas. Offered in<br />

alternate years.—II. Heyer<br />

290C. Advanced Research Conference (1)<br />

Discussion/conference—1 hour. Prerequisite: graduate<br />

standing and/or consent of instructor. Presentation<br />

and critical discussion of staff research activities.<br />

Designed for advanced graduate students. May be<br />

repeated for credit. (S/U grading only.)—I, II, III. (I,<br />

II, III.)<br />

291. Selected Topics in Microbiology (1)<br />

Seminar—1 hour. Prerequisite: graduate standing<br />

and consent of instructor. Current progress in microbiology<br />

and cellular and molecular biology. May be<br />

repeated for credit. (S/U grading only.)—I, II, III. (I,<br />

II, III.)<br />

292. Seminar in Bacterial Physiology and<br />

Genetics (1)<br />

Seminar—1 hour. Prerequisite: consent of instructor,<br />

graduate standing in microbiology or closely related<br />

field. Review and discussion of current research and<br />

literature in bacterial physiology and genetics, with<br />

presentations by individual students. (S/U grading<br />

only.)—I, II, III. (I, II, III.)<br />

296. Seminar in Animal Virology (1)<br />

Seminar—1 hour. Prerequisite: graduate-level standing<br />

or consent of instructor. A discussion of the current<br />

topics in animal virology. (Same course as<br />

Pathology, Microbiology, and Immunology 292A.)<br />

May be repeated for credit. (S/U grading only.)—I,<br />

II, III. (I, II, III.)<br />

298. Group Study (1-5)<br />

Prerequisite: consent of instructor. (S/U grading<br />

only.)<br />

299. Research (1-12)<br />

(S/U grading only.)<br />

Professional Course<br />

396. Teaching Assistant Training Practicum<br />

(1-4)<br />

Prerequisite: graduate standing. May be repeated<br />

for credit. (S/U grading only.)—I, II, III. (I, II, III.)<br />

Microbiology<br />

(A Graduate Group)<br />

Jay V. Solnick, Ph.D., Chairperson of the Group<br />

Group Office. 3143 Tupper Hall (Medical Microbiology<br />

and Immunology)<br />

(530) 752-0262<br />

Faculty<br />

Enoch P. Baldwin, Ph.D., Assistant Professor<br />

(Molecular and Cellular Biology)<br />

Peter A. Barry, Ph.D., Assistant Professor<br />

(Comparative Medicine)<br />

Stephen W. Barthold, Ph.D., Professor<br />

(Pathology, Microbiology, and Immunology)<br />

Nicole Baumgarth, Ph.D., Associate Professor<br />

(Center for Comparative Medicine)<br />

Andreas Baumler, Ph.D., Professor<br />

(Medical Microbiology and Immunology)<br />

Blaine L. Beaman, Ph.D., Professor<br />

(Medical Microbiology and Immunology)<br />

Charles L. Bevins, Ph.D., Professor<br />

(Medical Microbiology and Immunology)<br />

Linda F. Bisson, Ph.D., Professor<br />

(Viticulture and Enology)<br />

Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2009-<strong>2010</strong> offering in parentheses<br />

<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience

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