UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
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Microbiology (A Graduate Group) 401<br />
structure, replication and genetics. Only three units<br />
to students who have completed Pathology, Microbiology,<br />
and Immunology 128.—II. (II.) Falk, Manning<br />
170. Yeast Molecular Genetics (3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101; 102 or 105; Microbiology 102 or 140<br />
strongly recommended. Survey of the genetics, cell<br />
biology and technologies in yeasts and related<br />
lower eukaryotes. Topics include diversity of yeasts;<br />
cell structure; metabolism; cell cycle; genetic<br />
approaches and genomics; gene expression; yeasts<br />
as models to study higher eukaryotes; and contemporary<br />
techniques.—III. (III.) Shiozaki<br />
170. Yeast Molecular Genetics (3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101 and 102; course 102 or 140 (may be take concurrently)<br />
strongly recommended. Survey of the<br />
genetics, cell biology and technologies in yeasts and<br />
related lower eukaryotes. Topics include diversity of<br />
yeasts; cell structure; metabolism; cell cycle; genetic<br />
approaches and genomics; gene expression; yeasts<br />
as models to study higher eukaryotes; and contemporary<br />
techniques.—III. (III.) Shiozaki<br />
190C. Undergraduate Research Conference<br />
(1)<br />
Discussion—1 hour. Prerequisite: upper division<br />
standing and consent of instructor, course 199 concurrently.<br />
Presentation and critical discussion of staff<br />
research activities: designed for advanced undergraduate<br />
students. May be repeated for credit. (P/<br />
NP grading only.)—I, II, III. (I, II, III.)<br />
191. Introduction to Research for Advanced<br />
Undergraduates (1)<br />
Seminar—1 hour. Prerequisite: Biological Sciences<br />
1A or 2A or consent of instructor. Discussion of faculty<br />
research focusing on the biochemistry, genetics,<br />
and cell biology of microorganisms, along with<br />
ways undergraduates can participate in research<br />
projects of faculty members. May be repeated three<br />
times for credit. (P/NP grading only.)—III. (III.)<br />
192. Internship (1-12)<br />
Internship—3-36 hours. Technical and/or professional<br />
experience on or off campus. Supervised by a<br />
member of the Microbiology Section faculty. (P/NP<br />
grading only.)<br />
194H. Microbiology Honors Research (2)<br />
Independent study—6 hours. Prerequisite: senior<br />
standing; eligibility for college honors; completion of<br />
six units of 199 in microbiology; consent of section.<br />
Continuation of an individual microbiological<br />
research project culminating in writing of a senior<br />
thesis under a faculty director. (P/NP grading only.)<br />
197T. Tutoring in Microbiology (1-12)<br />
Prerequisite: upper division standing and consent of<br />
instructor. Assisting the instructor in one of the section’s<br />
regular courses by tutoring individual or small<br />
groups of students in a laboratory, in voluntary discussion<br />
groups, or other voluntary course activities.<br />
May be repeated for credit. (P/NP grading only.)—<br />
I, II, III. (I, II, III.)<br />
198. Directed Group Study (1-5)<br />
Prerequisite: consent of instructor. (P/NP grading<br />
only.)<br />
199. Special Study for Advanced<br />
Undergraduates (1-5)<br />
Prerequisite: consent of instructor. (P/NP grading<br />
only.)<br />
Graduate Courses<br />
200A. Biology of Prokaryotes (3)<br />
Lecture—3 hours. Prerequisite: course 102 or the<br />
equivalent. Intended for first year graduate students<br />
in microbiology and closely related fields. Overview<br />
of prokaryotic biology, with emphasis on phylogeny,<br />
physiology, and diversity of bacteria.—I. (I.)<br />
200B. Advanced Bacteriology (3)<br />
Lecture—3 hours. Prerequisite: course 200A.<br />
Intended for first year graduate students in microbiology<br />
and closely related fields. Advanced topics in<br />
phylogeny, physiology, and diversity of bacteria.<br />
Not offered every year.—II. (II.)<br />
201L. Advanced Microbiology Laboratory<br />
Rotations (5)<br />
Laboratory—15 hours. Prerequisite: course 200A<br />
(may be taken concurrently). Two five-week assignments<br />
in microbiology research laboratories. Individual<br />
research problems with emphasis on<br />
methodological/procedural experience and experimental<br />
design. May be repeated twice for credit.—I,<br />
II. (I, II.)<br />
210. Molecular Mechanisms in Microbial<br />
Pathogenesis (3)<br />
Lecture—3 hours. Prerequisite: course 105 or Veterinary<br />
Microbiology 127 and course 162 or Veterinary<br />
Microbiology 128 or the equivalent. Study of<br />
the molecular mechanisms involved in cytopathogenesis<br />
of higher eukaryotic organisms. Emphasis on the<br />
alteration or inhibition of cellular metabolism and<br />
function by bacteria and animal viruses. Not offered<br />
every year.<br />
215. Recombinant DNA (3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101, 102, 103 or the equivalent. Application of<br />
recombinant DNA technology to modern problems<br />
in biology, biochemistry, and genetics, emphasizing<br />
molecular cloning strategies, choice of vectors, preparation<br />
of insert DNA, and selection procedures.—I.<br />
(I.) Privalsky<br />
250. Biology of Yeasts (5)<br />
Lecture—3 hours; discussion—2 hours. Prerequisite:<br />
Biological Sciences 102, 103; course 102, 102L;<br />
course 215 recommended. Survey of the genetics,<br />
physiology, metabolism, regulatory mechanisms,<br />
structure, cell biology, ecology and diversity of<br />
yeasts and related organisms. Not offered every<br />
year.<br />
260. Bacterial Genetic Regulatory<br />
Mechanisms (3)<br />
Lecture/discussion—3 hours. Prerequisite: general<br />
knowledge of nucleic acid biochemistry and bacterial<br />
genetics. Analysis at the molecular level of<br />
genetic regulation in selected bacterial systems. Specific<br />
systems discussed will include the following<br />
types of regulation: control of transcription initiation<br />
and termination; translational controls; tRNA modification<br />
effects; autoregulation; control circuits in bacterial<br />
viruses; supercontrols. Not offered every year.<br />
262. Advanced <strong>General</strong> and Molecular<br />
Virology (3)<br />
Lecture—3 hours. Prerequisite: graduate standing.<br />
Advanced integrated presentation of animal, bacterial,<br />
and plant viruses, including their structure,<br />
modes of regulation, expression and replication,<br />
and effects on host cells and organisms.—II. Bruening<br />
263. Principles of Protein–Nucleic Acid<br />
Interactions (3)<br />
Lecture—3 hours. Prerequisite: advanced graduate<br />
standing and completion of one year of basic graduate<br />
course work in biochemistry, biophysics, chemistry,<br />
genetics, microbiology, or molecular biology.<br />
Physical basis of protein–nucleic acid interaction.<br />
Topics include nucleic acid recognition by proteins,<br />
thermodynamics of protein–nucleic acid stability,<br />
and kinetics of binding process for both non-specific<br />
and sequence-specific nucleic acid binding proteins.<br />
Emphasis on systems that represent paradigms in<br />
protein–nucleic acid interactions. Not offered every<br />
year.<br />
274. Seminar in Genetic Recombination (1)<br />
Seminar—1 hour. Prerequisite: graduate standing;<br />
consent of instructor. Biochemical and genetic<br />
aspects of genetic recombination in prokaryotes and<br />
eukaryotes. Mechanisms of recombination and biochemical<br />
and genetic characteristics of recombination<br />
proteins. Proteins include DNA strand<br />
exchange, DNA helicases, and Holliday junction<br />
resolving proteins. May be repeated for credit. Not<br />
offered every year. (S/U grading only.)<br />
275. Seminar in DNA Repair and<br />
Recombination (1)<br />
Seminar—1 hour. Prerequisite: consent of instructor;<br />
graduate standing in Microbiology or closely related<br />
field. Review and discussion of current research and<br />
literature in DNA repair and recombination with presentations<br />
by individual students and invited speakers.<br />
May be repeated for credit. (S/U grading<br />
only.)—I, II, III. (I, II, III.) Heyer<br />
276. Advanced Concepts in DNA<br />
Metabolism (3)<br />
Lecture—3 hours. Prerequisite: Molecular and Cellular<br />
Biology 221C or Genetics 201C or equivalent<br />
course recommended. DNA damage checkpoints,<br />
homologous recombination, and meiotic recombination.<br />
An advanced treatment of the clinical and current<br />
literature to discuss emerging principles and<br />
current models in these research areas. Offered in<br />
alternate years.—II. Heyer<br />
290C. Advanced Research Conference (1)<br />
Discussion/conference—1 hour. Prerequisite: graduate<br />
standing and/or consent of instructor. Presentation<br />
and critical discussion of staff research activities.<br />
Designed for advanced graduate students. May be<br />
repeated for credit. (S/U grading only.)—I, II, III. (I,<br />
II, III.)<br />
291. Selected Topics in Microbiology (1)<br />
Seminar—1 hour. Prerequisite: graduate standing<br />
and consent of instructor. Current progress in microbiology<br />
and cellular and molecular biology. May be<br />
repeated for credit. (S/U grading only.)—I, II, III. (I,<br />
II, III.)<br />
292. Seminar in Bacterial Physiology and<br />
Genetics (1)<br />
Seminar—1 hour. Prerequisite: consent of instructor,<br />
graduate standing in microbiology or closely related<br />
field. Review and discussion of current research and<br />
literature in bacterial physiology and genetics, with<br />
presentations by individual students. (S/U grading<br />
only.)—I, II, III. (I, II, III.)<br />
296. Seminar in Animal Virology (1)<br />
Seminar—1 hour. Prerequisite: graduate-level standing<br />
or consent of instructor. A discussion of the current<br />
topics in animal virology. (Same course as<br />
Pathology, Microbiology, and Immunology 292A.)<br />
May be repeated for credit. (S/U grading only.)—I,<br />
II, III. (I, II, III.)<br />
298. Group Study (1-5)<br />
Prerequisite: consent of instructor. (S/U grading<br />
only.)<br />
299. Research (1-12)<br />
(S/U grading only.)<br />
Professional Course<br />
396. Teaching Assistant Training Practicum<br />
(1-4)<br />
Prerequisite: graduate standing. May be repeated<br />
for credit. (S/U grading only.)—I, II, III. (I, II, III.)<br />
Microbiology<br />
(A Graduate Group)<br />
Jay V. Solnick, Ph.D., Chairperson of the Group<br />
Group Office. 3143 Tupper Hall (Medical Microbiology<br />
and Immunology)<br />
(530) 752-0262<br />
Faculty<br />
Enoch P. Baldwin, Ph.D., Assistant Professor<br />
(Molecular and Cellular Biology)<br />
Peter A. Barry, Ph.D., Assistant Professor<br />
(Comparative Medicine)<br />
Stephen W. Barthold, Ph.D., Professor<br />
(Pathology, Microbiology, and Immunology)<br />
Nicole Baumgarth, Ph.D., Associate Professor<br />
(Center for Comparative Medicine)<br />
Andreas Baumler, Ph.D., Professor<br />
(Medical Microbiology and Immunology)<br />
Blaine L. Beaman, Ph.D., Professor<br />
(Medical Microbiology and Immunology)<br />
Charles L. Bevins, Ph.D., Professor<br />
(Medical Microbiology and Immunology)<br />
Linda F. Bisson, Ph.D., Professor<br />
(Viticulture and Enology)<br />
Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2009-<strong>2010</strong> offering in parentheses<br />
<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience