UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
UC Davis 2008-2010 General Catalog - General Catalog - UC Davis
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Molecular and Cellular Biology 407<br />
The Biochemistry and Molecular<br />
Biology Major Program<br />
The Biochemistry and Molecular Biology major introduces<br />
students to the chemistry of living organisms<br />
and the experimental techniques that are used to<br />
probe the structures and functions of biologically<br />
important molecules. Students who enjoy both chemistry<br />
and biology and who are comfortable with<br />
quantitative approaches to problem solving will find<br />
this major a rewarding field of study.<br />
The Program. The biochemistry and molecular<br />
biology program begins with the four-course, upper<br />
division common curriculum that provides an introduction<br />
to the principles of biochemistry, genetics,<br />
and cell biology. Majors then take a comprehensive<br />
and rigorous laboratory course to familiarize them<br />
with the most important aspects of biochemical<br />
research. Additional upper division courses in biochemistry<br />
and molecular biology examine detailed<br />
aspects of these subjects. Students are also required<br />
to take courses in other biological sciences and a full<br />
year of physical chemistry.<br />
Career Alternatives. The biochemistry and<br />
molecular biology program provides a solid scientific<br />
background for students seeking a research,<br />
teaching, or service career in the life sciences. Positions<br />
are open to biochemists in bio-medical, biotechnological,<br />
pharmaceutical, agricultural research<br />
and chemical industries. Also, university-affiliated<br />
research laboratories, hospital laboratories, and<br />
government-sponsored research facilities provide<br />
employment opportunities. The major provides excellent<br />
preparation for advanced study in graduate or<br />
professional schools.<br />
B.S. Major Requirements:<br />
UNITS<br />
Preparatory Subject Matter.............. 53-57<br />
Biological Sciences 2A-2B-2C................ 14<br />
Chemistry 2A-2B-2C or 2AH-2BH-2CH ... 15<br />
Mathematics 16A-16B-16C, 17A-17B-17C or<br />
21A-21B-21C................................... 9-12<br />
Physics 7A-7B-7C................................. 12<br />
Statistics 13, 32, 100 (recommended) or<br />
102................................................... 3-4<br />
Depth Subject Matter ....................... 53-54<br />
Biological Sciences 101, 102, 103,<br />
104.................................................... 13<br />
Chemistry 118A-118B-118C or 128A-<br />
128B-128C, 129A-129B ................. 12-13<br />
Chemistry 107A-107B............................ 6<br />
Molecular and Cellular Biology 120L, 121,<br />
123, 124............................................ 16<br />
Restricted Electives ................................. 6<br />
6 units of upper division courses in<br />
biological sciences or chemistry relevant to<br />
the student's interest chosen in consultation<br />
with the adviser. Students are encouraged<br />
to obtain additional laboratory experience;<br />
however, no more than 3 units of 192, 193<br />
or 199 research may be counted toward<br />
restricted elective units.<br />
Total Units for the Major .............. 106-111<br />
Master Adviser. C.S. Gasser<br />
Advising Center for the major is located in 156<br />
Briggs (530) 752-9032.<br />
Graduate Study. See Biochemistry and Molecular<br />
Biology (A Graduate Group), on page 165.<br />
The Cell Biology Major Program<br />
The Cell Biology major program provides students<br />
with a comprehensive understanding of the cell, the<br />
basic structural and functional unit of all living organisms.<br />
The Program. To understand living organisms, the<br />
biologist must understand the cell. Hence, cell biology<br />
lies at the core of the biological sciences. Students<br />
taking this major gain a solid foundation in<br />
biological principles. The major emphasizes how<br />
cellular organization and function contribute to the<br />
development, maintenance and reproduction of<br />
adult organisms. The major illustrates the ways in<br />
which principles derived from the physical sciences,<br />
genetics, biochemistry, molecular biology and physiology<br />
are integrated in the study of living cells and<br />
emphasizes the experimental nature of the study of<br />
cell biology.<br />
Career Alternatives. The major provides an<br />
excellent background for students wishing to enter<br />
postgraduate and professional programs in biological,<br />
health sciences or veterinary sciences; for students<br />
pursuing careers involving teaching or<br />
research in the biological sciences; for students interested<br />
in careers in the biotechnological or pharmaceutical<br />
industries; or for students interested in<br />
careers related to the administrative, legal or commercial<br />
aspects of biomedical science.<br />
B.S. Major Requirements:<br />
UNITS<br />
Preparatory Subject Matter..............60-69<br />
Biological Sciences 2A-2B-2C................ 14<br />
Chemistry 2A-2B-2C............................. 15<br />
Mathematics 16A-16B-16C or<br />
17A-17B-17C or 21A-21B-21C ...........9-12<br />
Physics 7A-7B-7C................................. 12<br />
Statistics 13 or 100 (recommended)......... 4<br />
Chemistry 8A-8B or 118A-118B-<br />
118C ...............................................6-12<br />
Depth Subject Matter .......................42-43<br />
Biological Sciences 101, 102, 103,<br />
104 ................................................... 13<br />
Molecular and Cellular Biology 140L ....... 5<br />
Two courses from Molecular and Cellular<br />
Biology 143, 144, or 145...................... 6<br />
Molecular and Cellular Biology 121 or<br />
161 ..................................................... 3<br />
Molecular and Cellular Biology 150<br />
and 150L, or 163 and 164 ..................5-6<br />
Select at least 10 additional units from the<br />
following: Chemistry 107A, 107B; Evolution<br />
and Ecology 100, 150; Microbiology 102,<br />
150, 170; Molecular and Cellular Biology<br />
120L, 123, 124, 126, 138, 143, 144, 145,<br />
148, 150/150L, 158, 160L, 162, 163,<br />
164, 178, 182, 191; Neurobiology,<br />
Physiology, and Behavior 100, 101, 103,<br />
112, 131, 160, 161; Pathology,<br />
Microbiology, and Immunology 126, 126L;<br />
Plant Biology 111, 111D, 113, 113D, 152.<br />
No more than 4 units of research (193,<br />
194H, 199) may be used for credit in this<br />
category ............................................. 10<br />
Total Units for the Major ..............102-112<br />
Master Adviser. D.G. Myles<br />
Advising Center for the major is located in 156<br />
Briggs (530) 752-0202.<br />
Graduate Study. See Cell and Developmental<br />
Biology (A Graduate Group), on page 174.<br />
The Genetics Major Program<br />
The Genetics major provides a broad background in<br />
the biological, mathematical, and physical sciences<br />
basic to the study of heredity, gene expression and<br />
evolution. The major is sufficiently flexible to accommodate<br />
students interested in the subject either as a<br />
basic discipline in the biological sciences or in terms<br />
of its applied aspects such as biotechnology, medicine,<br />
and agriculture.<br />
The Program. The genetics program begins with<br />
the four-course, upper division core curriculum that<br />
provides an introduction to the principles of genetics,<br />
biochemistry, and cell biology. Students then take<br />
additional upper division courses in specialized<br />
areas of modern genetics including gene expression,<br />
evolution, development, human genetics and genomics,<br />
as well as a laboratory course in the principles<br />
of genetics. Additional upper division courses in biological<br />
sciences, as well as internship/research<br />
coursework can be chosen to fulfill required elective<br />
units.<br />
Career Alternatives. The genetics degree provides<br />
suitable preparation for a wide variety of<br />
careers, including teaching, research, work with biotechnology<br />
companies, medicine, and all the health<br />
sciences. It is also an excellent background for students<br />
wishing to continue their education in a graduate<br />
program, a teacher-training program, medical<br />
school, veterinary school, or other professional<br />
schools.<br />
B.S. Major Requirements:<br />
UNITS<br />
Preparatory Subject Matter..............56-65<br />
Biological Sciences 2A-2B-2C ................14<br />
Chemistry 2A-2B-2C or 2AH-2BH-<br />
2CH....................................................15<br />
Chemistry 8A-8B or 118A-118B-<br />
118C...............................................6-12<br />
Mathematics 16A-16B-16C or 1<br />
7A-17B-17C or 21A-21B-21C.............9-12<br />
Physics 7A-7B-7C .................................12<br />
Depth Subject Matter .......................48-49<br />
Biological Sciences 101, 102, 103,<br />
104 ....................................................13<br />
Molecular and Cellular Biology 160L,<br />
164 ......................................................7<br />
Evolution and Ecology 100 ......................4<br />
One course from Molecular and Cellular<br />
Biology 161 (recommended) or 121.........3<br />
Two courses from Molecular and Cellular<br />
Biology 162, 163, 182 or Evolution and<br />
Ecology 102 .......................................6-7<br />
Statistics 100 .........................................4<br />
Restricted Electives ................................11<br />
Upper division courses in genetics or other<br />
fields relevant to the student's interest<br />
chosen in consultation with the adviser. No<br />
more than 4 units of 192, 193, 198, or<br />
199 may be used for credit in this category.<br />
Total Units for the Major ..............104-114<br />
Master Adviser. J.E. Natzle<br />
Advising Center for the major is located in 156<br />
Briggs Hall (530) 752-0202.<br />
Graduate Study. See Genetics (A Graduate<br />
Group), on page 302.<br />
Courses in Molecular and Cellular<br />
Biology (MCB)<br />
Lower Division Courses<br />
10. Introduction to Human Heredity (4)<br />
Lecture—3 hours; discussion—1 hour. Topics in<br />
human heredity and human gene structure and function,<br />
including the genetic basis of human development,<br />
causes of birth defects, mental retardation,<br />
genetic diseases, sexual determination, development,<br />
and behavior. GE credit: SciEng.—III. (III.)<br />
Sanders<br />
99. Special Study (1-5)<br />
Independent study—3-15 hours. Prerequisite: consent<br />
of instructor. (P/NP grading only.)<br />
Upper Division Courses<br />
120L. Biochemistry Laboratory (6)<br />
Laboratory—10 hours; lecture—2 hours; laboratory/discussion—1<br />
hour. Prerequisite: Biological Sciences<br />
103 (may be taken concurrently). Introduction<br />
to laboratory methods and procedures employed in<br />
studying biochemical processes. Designed for students<br />
who need experience in the use of biochemical<br />
techniques as laboratory tools.—I, II, III. (I, II, III.)<br />
Fairclough, Hilt, Lagarias, Lindsay, Liu, L. Morand,<br />
Rubin<br />
121. Molecular Biology of Eukaryotic Cells<br />
(3)<br />
Lecture—3 hours. Prerequisite: Biological Sciences<br />
101 and 103. Structure, expression, and regulation<br />
of eukaryotic genes. Chromosome structure and replication;<br />
gene structure, transcription, and RNA processing;<br />
protein synthesis and translation control;<br />
development, immune system, and oncogenes. Not<br />
open for credit to students who have completed<br />
Molecular and Cellular Biology 161.—II, III. (II, III.)<br />
Burgess, Dahmus, Gasser, Harmer<br />
Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2009-<strong>2010</strong> offering in parentheses<br />
<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience