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UC Davis 2008-2010 General Catalog - General Catalog - UC Davis

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Molecular and Cellular Biology 407<br />

The Biochemistry and Molecular<br />

Biology Major Program<br />

The Biochemistry and Molecular Biology major introduces<br />

students to the chemistry of living organisms<br />

and the experimental techniques that are used to<br />

probe the structures and functions of biologically<br />

important molecules. Students who enjoy both chemistry<br />

and biology and who are comfortable with<br />

quantitative approaches to problem solving will find<br />

this major a rewarding field of study.<br />

The Program. The biochemistry and molecular<br />

biology program begins with the four-course, upper<br />

division common curriculum that provides an introduction<br />

to the principles of biochemistry, genetics,<br />

and cell biology. Majors then take a comprehensive<br />

and rigorous laboratory course to familiarize them<br />

with the most important aspects of biochemical<br />

research. Additional upper division courses in biochemistry<br />

and molecular biology examine detailed<br />

aspects of these subjects. Students are also required<br />

to take courses in other biological sciences and a full<br />

year of physical chemistry.<br />

Career Alternatives. The biochemistry and<br />

molecular biology program provides a solid scientific<br />

background for students seeking a research,<br />

teaching, or service career in the life sciences. Positions<br />

are open to biochemists in bio-medical, biotechnological,<br />

pharmaceutical, agricultural research<br />

and chemical industries. Also, university-affiliated<br />

research laboratories, hospital laboratories, and<br />

government-sponsored research facilities provide<br />

employment opportunities. The major provides excellent<br />

preparation for advanced study in graduate or<br />

professional schools.<br />

B.S. Major Requirements:<br />

UNITS<br />

Preparatory Subject Matter.............. 53-57<br />

Biological Sciences 2A-2B-2C................ 14<br />

Chemistry 2A-2B-2C or 2AH-2BH-2CH ... 15<br />

Mathematics 16A-16B-16C, 17A-17B-17C or<br />

21A-21B-21C................................... 9-12<br />

Physics 7A-7B-7C................................. 12<br />

Statistics 13, 32, 100 (recommended) or<br />

102................................................... 3-4<br />

Depth Subject Matter ....................... 53-54<br />

Biological Sciences 101, 102, 103,<br />

104.................................................... 13<br />

Chemistry 118A-118B-118C or 128A-<br />

128B-128C, 129A-129B ................. 12-13<br />

Chemistry 107A-107B............................ 6<br />

Molecular and Cellular Biology 120L, 121,<br />

123, 124............................................ 16<br />

Restricted Electives ................................. 6<br />

6 units of upper division courses in<br />

biological sciences or chemistry relevant to<br />

the student's interest chosen in consultation<br />

with the adviser. Students are encouraged<br />

to obtain additional laboratory experience;<br />

however, no more than 3 units of 192, 193<br />

or 199 research may be counted toward<br />

restricted elective units.<br />

Total Units for the Major .............. 106-111<br />

Master Adviser. C.S. Gasser<br />

Advising Center for the major is located in 156<br />

Briggs (530) 752-9032.<br />

Graduate Study. See Biochemistry and Molecular<br />

Biology (A Graduate Group), on page 165.<br />

The Cell Biology Major Program<br />

The Cell Biology major program provides students<br />

with a comprehensive understanding of the cell, the<br />

basic structural and functional unit of all living organisms.<br />

The Program. To understand living organisms, the<br />

biologist must understand the cell. Hence, cell biology<br />

lies at the core of the biological sciences. Students<br />

taking this major gain a solid foundation in<br />

biological principles. The major emphasizes how<br />

cellular organization and function contribute to the<br />

development, maintenance and reproduction of<br />

adult organisms. The major illustrates the ways in<br />

which principles derived from the physical sciences,<br />

genetics, biochemistry, molecular biology and physiology<br />

are integrated in the study of living cells and<br />

emphasizes the experimental nature of the study of<br />

cell biology.<br />

Career Alternatives. The major provides an<br />

excellent background for students wishing to enter<br />

postgraduate and professional programs in biological,<br />

health sciences or veterinary sciences; for students<br />

pursuing careers involving teaching or<br />

research in the biological sciences; for students interested<br />

in careers in the biotechnological or pharmaceutical<br />

industries; or for students interested in<br />

careers related to the administrative, legal or commercial<br />

aspects of biomedical science.<br />

B.S. Major Requirements:<br />

UNITS<br />

Preparatory Subject Matter..............60-69<br />

Biological Sciences 2A-2B-2C................ 14<br />

Chemistry 2A-2B-2C............................. 15<br />

Mathematics 16A-16B-16C or<br />

17A-17B-17C or 21A-21B-21C ...........9-12<br />

Physics 7A-7B-7C................................. 12<br />

Statistics 13 or 100 (recommended)......... 4<br />

Chemistry 8A-8B or 118A-118B-<br />

118C ...............................................6-12<br />

Depth Subject Matter .......................42-43<br />

Biological Sciences 101, 102, 103,<br />

104 ................................................... 13<br />

Molecular and Cellular Biology 140L ....... 5<br />

Two courses from Molecular and Cellular<br />

Biology 143, 144, or 145...................... 6<br />

Molecular and Cellular Biology 121 or<br />

161 ..................................................... 3<br />

Molecular and Cellular Biology 150<br />

and 150L, or 163 and 164 ..................5-6<br />

Select at least 10 additional units from the<br />

following: Chemistry 107A, 107B; Evolution<br />

and Ecology 100, 150; Microbiology 102,<br />

150, 170; Molecular and Cellular Biology<br />

120L, 123, 124, 126, 138, 143, 144, 145,<br />

148, 150/150L, 158, 160L, 162, 163,<br />

164, 178, 182, 191; Neurobiology,<br />

Physiology, and Behavior 100, 101, 103,<br />

112, 131, 160, 161; Pathology,<br />

Microbiology, and Immunology 126, 126L;<br />

Plant Biology 111, 111D, 113, 113D, 152.<br />

No more than 4 units of research (193,<br />

194H, 199) may be used for credit in this<br />

category ............................................. 10<br />

Total Units for the Major ..............102-112<br />

Master Adviser. D.G. Myles<br />

Advising Center for the major is located in 156<br />

Briggs (530) 752-0202.<br />

Graduate Study. See Cell and Developmental<br />

Biology (A Graduate Group), on page 174.<br />

The Genetics Major Program<br />

The Genetics major provides a broad background in<br />

the biological, mathematical, and physical sciences<br />

basic to the study of heredity, gene expression and<br />

evolution. The major is sufficiently flexible to accommodate<br />

students interested in the subject either as a<br />

basic discipline in the biological sciences or in terms<br />

of its applied aspects such as biotechnology, medicine,<br />

and agriculture.<br />

The Program. The genetics program begins with<br />

the four-course, upper division core curriculum that<br />

provides an introduction to the principles of genetics,<br />

biochemistry, and cell biology. Students then take<br />

additional upper division courses in specialized<br />

areas of modern genetics including gene expression,<br />

evolution, development, human genetics and genomics,<br />

as well as a laboratory course in the principles<br />

of genetics. Additional upper division courses in biological<br />

sciences, as well as internship/research<br />

coursework can be chosen to fulfill required elective<br />

units.<br />

Career Alternatives. The genetics degree provides<br />

suitable preparation for a wide variety of<br />

careers, including teaching, research, work with biotechnology<br />

companies, medicine, and all the health<br />

sciences. It is also an excellent background for students<br />

wishing to continue their education in a graduate<br />

program, a teacher-training program, medical<br />

school, veterinary school, or other professional<br />

schools.<br />

B.S. Major Requirements:<br />

UNITS<br />

Preparatory Subject Matter..............56-65<br />

Biological Sciences 2A-2B-2C ................14<br />

Chemistry 2A-2B-2C or 2AH-2BH-<br />

2CH....................................................15<br />

Chemistry 8A-8B or 118A-118B-<br />

118C...............................................6-12<br />

Mathematics 16A-16B-16C or 1<br />

7A-17B-17C or 21A-21B-21C.............9-12<br />

Physics 7A-7B-7C .................................12<br />

Depth Subject Matter .......................48-49<br />

Biological Sciences 101, 102, 103,<br />

104 ....................................................13<br />

Molecular and Cellular Biology 160L,<br />

164 ......................................................7<br />

Evolution and Ecology 100 ......................4<br />

One course from Molecular and Cellular<br />

Biology 161 (recommended) or 121.........3<br />

Two courses from Molecular and Cellular<br />

Biology 162, 163, 182 or Evolution and<br />

Ecology 102 .......................................6-7<br />

Statistics 100 .........................................4<br />

Restricted Electives ................................11<br />

Upper division courses in genetics or other<br />

fields relevant to the student's interest<br />

chosen in consultation with the adviser. No<br />

more than 4 units of 192, 193, 198, or<br />

199 may be used for credit in this category.<br />

Total Units for the Major ..............104-114<br />

Master Adviser. J.E. Natzle<br />

Advising Center for the major is located in 156<br />

Briggs Hall (530) 752-0202.<br />

Graduate Study. See Genetics (A Graduate<br />

Group), on page 302.<br />

Courses in Molecular and Cellular<br />

Biology (MCB)<br />

Lower Division Courses<br />

10. Introduction to Human Heredity (4)<br />

Lecture—3 hours; discussion—1 hour. Topics in<br />

human heredity and human gene structure and function,<br />

including the genetic basis of human development,<br />

causes of birth defects, mental retardation,<br />

genetic diseases, sexual determination, development,<br />

and behavior. GE credit: SciEng.—III. (III.)<br />

Sanders<br />

99. Special Study (1-5)<br />

Independent study—3-15 hours. Prerequisite: consent<br />

of instructor. (P/NP grading only.)<br />

Upper Division Courses<br />

120L. Biochemistry Laboratory (6)<br />

Laboratory—10 hours; lecture—2 hours; laboratory/discussion—1<br />

hour. Prerequisite: Biological Sciences<br />

103 (may be taken concurrently). Introduction<br />

to laboratory methods and procedures employed in<br />

studying biochemical processes. Designed for students<br />

who need experience in the use of biochemical<br />

techniques as laboratory tools.—I, II, III. (I, II, III.)<br />

Fairclough, Hilt, Lagarias, Lindsay, Liu, L. Morand,<br />

Rubin<br />

121. Molecular Biology of Eukaryotic Cells<br />

(3)<br />

Lecture—3 hours. Prerequisite: Biological Sciences<br />

101 and 103. Structure, expression, and regulation<br />

of eukaryotic genes. Chromosome structure and replication;<br />

gene structure, transcription, and RNA processing;<br />

protein synthesis and translation control;<br />

development, immune system, and oncogenes. Not<br />

open for credit to students who have completed<br />

Molecular and Cellular Biology 161.—II, III. (II, III.)<br />

Burgess, Dahmus, Gasser, Harmer<br />

Quarter Offered: I=Fall, II=Winter, III=Spring, IV=Summer; 2009-<strong>2010</strong> offering in parentheses<br />

<strong>General</strong> Education (GE) credit: ArtHum=Arts and Humanities; SciEng=Science and Engineering; SocSci=Social Sciences; Div=Social-Cultural Diversity; Wrt=Writing Experience

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