Clinical Biochemistry of Domestic Animals (Sixth Edition) - UMK ...
Clinical Biochemistry of Domestic Animals (Sixth Edition) - UMK ...
Clinical Biochemistry of Domestic Animals (Sixth Edition) - UMK ...
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Chapter | 9 Iron Metabolism and Its Disorders<br />
Barut , B. A. , Zhou , Y. , Minet , E. , Donovan , A. , Brownlie , A. , Balzan ,<br />
R. , Weiss , M. J. , Peters , L. L. , Kaplan , J. , Zon , L. I., and Paw , B. H.<br />
( 2006 ). Mit<strong>of</strong>errin is essential for erythroid iron assimilation . Nature<br />
440 , 96 – 100 .<br />
Shayeghi , M. , Latunde-Dada , G. O. , Oakhill , J. S. , Laftah , A. H. , Takeuchi ,<br />
K. , Halliday , N. , Khan , Y. , Warley , A. , McCann , F. E. , Hider , R. C. ,<br />
Frazer , D. M. , Anderson , G. J. , Vulpe , C. D. , Simpson , R. J., and<br />
McKie , A. T. ( 2005 ). Identification <strong>of</strong> an intestinal heme transporter .<br />
Cell 122 , 789 – 801 .<br />
Sheftel , A. D. , Zhang , A. S. , Brown , C. , Shirihai , O. S., and Ponka , P.<br />
(2007 ). Direct interorganellar transfer <strong>of</strong> iron from endosome to<br />
mitochondrion . Blood 110 , 125 – 132 .<br />
Simpson , K. W. , Meyer , D. J. , Boswood , A. , White , R. N., and Maskell , I. E.<br />
( 1997 ). Iron status and erythrocyte volume in dogs with congenital<br />
portosystemic vascular anomalies . J. Vet. Intern. Med. 11 , 14 – 19 .<br />
Smith , J. E. ( 1992 ). Iron metabolism in dogs and cats . Comp. Cont. Ed.<br />
Pract. Vet. 14 , 39 – 43 .<br />
Smith , J. E. ( 1997 ). Iron metabolism and its disorders . In “ <strong>Clinical</strong><br />
<strong>Biochemistry</strong> <strong>of</strong> <strong>Domestic</strong> <strong>Animals</strong> ” ( J. J. Kaneko , J. W. Harvey, and<br />
M. L. Bruss , Eds.) , pp. 223 – 238 . Academic Press , San Diego, CA .<br />
Smith , J. E., and Cipriano , J. E. ( 1987 ). Inflammation-induced changes<br />
in serum iron analytes and ceruloplasmin <strong>of</strong> Shetland ponies . Vet.<br />
Pathol. 24 , 354 – 356 .<br />
Smith , J. E. , Cipriano , J. E. , DeBowes , R., and Moore , K. ( 1986 a ). Iron<br />
deficiency and pseudo-iron deficiency in hospitalized horses . J. Am.<br />
Vet. Med. Assoc. 188 , 285 – 287 .<br />
Smith , J. E. , DeBowes , R. M., and Cipriano , J. E. ( 1986 b ). Exogenous<br />
corticosteroids increase serum iron concentrations in mature horses<br />
and ponies . J. Am. Vet. Med. Assoc. 188 , 1296 – 1298 .<br />
Smith , J. E. , Moore , K. , Boyington , D. , Pollmann , D. S., and Schoneweis , D.<br />
( 1984 a ). Serum ferritin and total iron-binding capacity to estimate<br />
iron storage in pigs . Vet. Pathol. 21 , 597 – 600 .<br />
Smith , J. E. , Moore , K. , Cipriano , J. E., and Morris , P. G. ( 1984 b ). Serum<br />
ferritin as a measure <strong>of</strong> stored iron in horses . J. Nutr. 114 , 677 – 681 .<br />
Soubasis , N. , Rallis , T. S. , Vlemmas , J. , Adamama-Moraitou , K.<br />
K. , Roubies , N. , Prassinos , N. N., and Brellou , G. ( 2006 ). J.<br />
Gastroenterol. Hepatol. 21 , 599 – 604 .<br />
Sprague , W. S. , Hackett , T. B. , Johnson , J. S., and Swardson-Olver , C. J.<br />
( 2003 ). Hemochromatosis secondary to repeated blood transfusions<br />
in a dog . Vet. Pathol. 40 , 334 – 337 .<br />
Starzynski , R. R. , Gralak , M. A. , Smuda , E., and Lipinski , P. ( 2004 ). A<br />
characterization <strong>of</strong> the activities <strong>of</strong> iron regulatory protein 1 in various<br />
farm animal species . Cell. Mol. Biol. Lett. 9 , 651 – 664 .<br />
Steele , T. M. , Frazer , D. M., and Anderson , G. J. ( 2005 ). Systemic regulation<br />
<strong>of</strong> intestinal iron absorption . IUBMB Life 57 , 499 – 503 .<br />
Steffen , D. J. , Elliott , G. S. , Leipold , H. W., and Smith , J. E. ( 1992 ).<br />
Congenital dyserythropoiesis and progressive alopecia in Polled<br />
Hereford calves: hematologic, biochemical, bone marrow cytologic,<br />
electrophoretic, and flow cytometric findings . J. Vet. Diagn. Invest. 4 ,<br />
31 – 37 .<br />
Steinberg , J. D., and Olver , C. S. ( 2005 ). Hematologic and biochemical<br />
abnormalities indicating iron deficiency are associated with decreased<br />
reticulocyte hemoglobin content (CHr) and reticulocyte volume<br />
(rMCV) in dogs . Vet. Clin. Pathol. 34 , 23 – 27 .<br />
Stewart , W. B. , Vassar , P. S., and Stone , R. S. ( 1953 ). Iron absorption in<br />
dogs during anemia due to acetylphenylhydrazine . J. Clin. Invest. 32 ,<br />
1225 – 1228 .<br />
Stohlman , F. , Howard , A., and Beland , A. ( 1963 ). Humoral regulation <strong>of</strong><br />
erythropoiesis. XII. Effect <strong>of</strong> erythropoietin and iron on cell size in<br />
iron deficiency anemia . Proc. Soc. Exp. Biol. Med. 113 , 986 – 988 .<br />
Stokol , T., and Blue , J. T. ( 1999 ). Pure red cell aplasia in cats: 9 cases<br />
(1989–1997) . J. Am. Vet. Med. Assoc. 214 , 75 – 79 .<br />
Stokol , T. , Blue , J. T., and French , T. W. ( 2000 ). Idiopathic pure red cell<br />
aplasia and nonregenerative immune-mediated anemia in dogs: 43<br />
cases (1988–1999) . J. Am. Vet. Med. Assoc. 216 , 1429 – 1436 .<br />
Theurl , I. , Mattle , V. , Seifert , M. , Mariani , M. , Marth , C., and Weiss , G.<br />
( 2006 ). Dysregulated monocyte iron homeostasis and erythropoietin<br />
formation in patients with anemia <strong>of</strong> chronic disease . Blood 107 ,<br />
4142 – 4148 .<br />
Torti , F. M., and Torti , S. V. ( 2002 ). Regulation <strong>of</strong> ferritin genes and protein<br />
. Blood 99 , 3505 – 3516 .<br />
Truksa , J. , Peng , H. , Lee , P., and Beutler , E. ( 2006 ). Bone morphogenetic<br />
proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently<br />
<strong>of</strong> Hfe, transferrin receptor 2 (Tfr2), and IL-6 . Proc. Natl.<br />
Acad. Sci. USA 103 , 10289 – 10293 .<br />
Underwood , E. J. ( 1977 ). “ Trace Elements in Human and Animal<br />
Nutrition . ” Academic Press , New York .<br />
van Miert , A. S. , van Duin , C. T., and Wensing , T. ( 1986 ). The effects <strong>of</strong><br />
ACTH, prednisolone and Escherichia coli endotoxin on some clinical<br />
haematological and blood biochemical parameters in dwarf goats .<br />
Vet. Q. 8 , 195 – 203 .<br />
van Miert , A. S. , van Duin , C. T., and Wensing , T. ( 1990 ). Fever and changes<br />
in plasma zinc and iron concentrations in the goat: the effects <strong>of</strong><br />
interferon inducers and recombinant IFN-alpha 2a . J. Comp. Pathol.<br />
103 , 289 – 300 .<br />
Vaulont , S. , Lou , D. Q. , Viatte , L., and Kahn , A. ( 2005 ). Of mice and<br />
men: the iron age . J. Clin. Invest. 115 , 2079 – 2082 .<br />
Verga Falzacappa , M. V., and Muckenthaler , M. U. ( 2005 ). Hepcidin:<br />
iron-hormone and anti-microbial peptide . Gene 364 , 37 – 44 .<br />
Verheijden , J. H. , van Miert , A. S. , Schotman , A. J., and van Duin , C. T.<br />
(1982 ). Plasma zinc and iron concentrations as measurements for evaluating<br />
the influence <strong>of</strong> endotoxin-neutralizing agents in Escherichia<br />
coli endotoxin-induced mastitis . Am. J. Vet. Res. 43 , 724 –728 .<br />
Vokurka , M. , Krijt , J. , Sulc , K., and Necas , E. (2006 ). Hepcidin mRNA levels<br />
in mouse liver respond to inhibition <strong>of</strong> erythropoiesis . Physiol. Res.<br />
55 , 667 – 674 .<br />
Wallace , D. F. , Summerville , L. , Lusby , P. E., and Subramaniam , V. N.<br />
( 2005 ). Prohepcidin localises to the Golgi compartment and secretory<br />
pathway in hepatocytes . J. Hepatol. 43 , 720 – 728 .<br />
Watanabe , K. , Hayashi , K. , Miyamoto , T. , Tanaka , M. , Okano , S., and<br />
Yamamoto , S. ( 2000 ). Characterization <strong>of</strong> ferritin and ferritinbinding<br />
proteins in canine serum . Biometals 13 , 57 – 63 .<br />
Watanabe , K. , Ozawa , M. , Ochiai , H. , Kamohara , H. , Iijima , N. , Negita , H. ,<br />
Orino , K., and Yamamoto , S. ( 1998 ). Changes in iron and ferritin in<br />
anemic calves infected with Theileria sergenti. J. Vet. Med. Sci. 60 ,<br />
943 – 947 .<br />
Weeks , B. R. , Smith , J. E. , DeBowes , R. M., and Smith , J. M. ( 1989 a ).<br />
Decreased serum iron and zinc concentrations in cattle receiving<br />
intravenous dexamethasone . Vet. Pathol. 26 , 345 – 346 .<br />
Weeks , B. R. , Smith , J. E., and Northrop , J. K. ( 1989 b ). Relationship <strong>of</strong><br />
serum ferritin and iron concentrations and serum total iron-binding<br />
capacity to nonheme iron stores in dogs . Am. J. Vet. Res. 50 ,<br />
198 – 200 .<br />
Weeks , B. R. , Smith , J. E., and Phillips , R. M. ( 1988 ). Enzyme-linked<br />
immunosorbent assay for canine serum ferritin, using monoclonal<br />
anti-canine ferritin immunoglobulin G . Am. J. Vet. Res. 49 ,<br />
1193 – 1196 .<br />
Weeks , B. R. , Smith , J. E., and Stadler , C. K. ( 1990 ). Effect <strong>of</strong> dietary<br />
iron content on hematologic and other measures <strong>of</strong> iron adequacy in<br />
dogs . J. Am. Vet. Med. Assoc. 196 , 749 – 753 .