Download (4Mb) - Etheses - Saurashtra University

Part-IResults and DiscussionTable-9. Physical data of condensed pyrimidinylmethylthiobenzimidazoles (IIIi-xxxv) synthesizedONHNSNHNYS. No. Y Mol. Formula(Sol. ofrecryst.)IIIiH C 18 H 16 N 4 OS 2(C-M)IIIiiIIIiiiIIIivIIIvOOOOOOSSSSSOCH 3 C 19 H 18 N 4 O 2 S 2(C-M)H C 17 H 14 N 4 O 3 S 2(C-M)OCH 3 C 18 H 16 N 4 O 4 S 2(C-M)H C 18 H 16 N 4 O 3 S 2(C-M)M.P ( o C) IR (cm -1 )(KBr)264-267 3247(γ NH ),2939(γ C-H ),1680(γ CONH ),743(γ C-S )210-215 3266(γ NH ),2940(γ C-H ),1670(γ CONH ),643(γ C-S ).258-260 3282(γ NH ),2956(γ C-H ),1667(γ CONH ),741(γ C-S )230-235 3339(γ NH ),2943(γ C-H ),1690(γ CONH ),613(γ C-S )270-272 3237(γ NH ),2945(γ C-H ),1716(γ COOEt ),1673(γ CONH ),740(γ C-S )Mass(m/e)368(M + ),335,307, 150398(M + ),365,219, 180386(M + ),353, 150416(M + ),383,210, 180400(M + ),365,215, 150NMR (δppm)(DMSO-d 6 )1.83-1.88 (4H, m, CH 2 at 6 & 7), 2.76 (2H, t, CH 2 at 5, J = 5.64),2.95 (2H, t, CH 2 at 8, J = 5.80), 4.39 (2H, s, CH 2 at SCH 2 ), 7.39-7.16 (4H, m, Ar-H), 12.50 (1H, s, NH), 13.17 (1H, s, NH)1.83-1.88 (4H, m, CH 2 at 6 & 7), 2.75 (2H, t, CH 2 at 5, J = 5), 2.97(2H, t, CH 2 at 8, J = 5), 3.87 (3H, s, OCH 3 ), 4.32 (2H, s, CH 2 atSCH 2 ), 6.81-7.25 (3H, m, Ar-H), 7.57 (1H, s, NH), 12.21 (1H, s,NH)2.90 (3H, s, CH 3 at 5), 3.87 (3H, s, CH 3 of CH 3 OOC), 4.36 (2H, s,CH 2 at SCH 2 ), 7.17 (2H, q, H at imidazole, J = 3.2), 7.53 (2H, q,imidazole, J = 3.16)2.68 (3H, s, CH 3 at 5), 3.86 (3H, s, OCH 3 ), 3.88 (3H, s, CH 3 -O-CO-), 4.65 (2H, s, CH 2 at SCH 2 ), 7.05 (1H, dd, CH at imidazole, J= 2.30 & 6.64), 7.15 (1H, d, CH at imidazole, J = 2.2), 7.54 (1H, d,CH at imidazole, J = 8.92), 12.47 (1H, br s, NH), 13.45 (1H, s,NH).--86