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Table 34: Physical data of 2-substitutedthieno[2,3-d]pyrimidin-4(3H)-onesPart-IISynthesis of PyrimidinesOR 2R 1SN NNR 3Conventional MethodMicrowave-Assisted MethodR 1 R 2 R 3 Yield(%)Mp ( o C) Time(h)Yield(%)Mp ( o C) Time(min.)-( CH 2 ) 4 - CH 3 66 300 8-10 68 298 75CH 3 CH 3 CH 3 76 256 10-12 89 256 604-CH 3 C 6 H 4 H CH 3 93 245 8-10 94 248 55CH 3 OOC 2 H 5 CH 3 71 262 8-10 85 262 40C 6 H 5 H CH 3 69 264 8-10 75 264 65-( CH 2 ) 4 - CH 2 CH 2 Cl 84 220 8-10 96* 218 45CH 3 CH 3 CH 2 CH 2 Cl 85 200 20-24 99 201 504-CH 3 C 6 H 4 H CH 2 CH 2 Cl 91 168 10-12 92* 169 35CH 3 COOC 2 H 5 CH 2 CH 2 Cl 85 167 8-10 88 167 20C 6 H 5 H CH 2 CH 2 Cl 94 268 8-10 96 267 45-( CH 2 ) 4 - CH 2 Cl 77 259 6-8 90 258 30CH 3 CH 3 CH 2 Cl 83 257 8-10 91 256 254-CH 3 C 6 H 4 H CH 2 Cl 88 248 6-8 93 249 40CH 3 COOC 2 H 5 CH 2 Cl 86 225 6-8 95 225 10C 6 H 5 H CH 2 Cl 90 215 6-8 91 214 35* Catalytic amount of anhydrous. AlCl 3 was added to the reaction mixture263