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Part-IIImpact of Microwave…OO+S 8CNMWI 2 o amineOORRORNH 2ONS HMWI POCl 3NHH 2NMWIOOMeSCNOMWINHSNSMWI NHR 1 R 2NH 2SMWI ClCH 2 CNONHNSMWI NHR 1 R 2H 2NCH 2 CHCN,MWIOMWINHClNSMWI NHR 1 R 2OClONHNSPOCl 3 MWIRClOOONNSMWI NHR 1 R 22 R 1 RNClNHNSPOCl 3 MWIClNR 1 R 2NHNSPOCl 3 MWIClNR 1 R 2NHNSPOCl 3 MWIClNR 1 R 2ClNNSMWI NHR 1 R 22 R 1 RNRNNSMWI NHR 3 R 4ClNNSMWI NHR 3 R 4NR 1 R 2NNSMWI NHR 3 R 4NR 1 R 2NHNSMWI NHR 3 R 4NR 1 R 2SNNR2 R 1 RN4 R 3 RN4 R 3 RN4 R 3 RNSNNNR 3 R 4SNNNR 1 R 2SNNScheme-3NR 1 R 2SNNHNR 1 R 22.4. ConclusionsThere are more than 5,000 documented examples of Microwave Assisted OrganicSynthesis (MAOS) reported by both academic and industrial laboratories, which suggeststhat most chemical transformations can be carried out successfully under microwaveconditions. This does not necessarily imply that dramatic rate-enhancements comparedwith a classical, thermal process will be observed in all cases, but the simple convenienceof using microwave technology will make this non-classical heating method a standardtool in the laboratory within a few years The recently reported incorporation of real time,in situ monitoring of microwave-assisted reactions by Raman spectroscopy will facilitatea further increase in efficiency and speed.For the production of New Chemical Entities (NCE’s) in pharmaceutical industry today,microwave is an essential tool and several laboratories have already incorporatedmicrowave reactors into in-house ‘synthesis stations’ for producing small- and mediumsizedcompound libraries in a high-throughput format.305