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Part-IIImpact of Microwave…Multigram quantities of the corresponding 4-aminopyrimidines which are potentialNCE’s, have been prepared in high yields and purity following a simple and scaleableprotocol. 49 R CNNH 2t-BuOKNRMWI, 160 o C,3x15 minRN50R = Ph, 4-OCH 3 Ph, 4-ClPh, 4-BrPh,(CH 2 ) 3 Ph, CH 2 Me, H, (CH 2 ) 3 Me etc.RA fast method has been developed for transition-metal-catalyzed decoration of 4-aryldihydropyrimidones(29 compounds) using controlled microwave heating as the energysource. The palladium-catalyzed protocols allow facile installation of diversities into 4-(bromoaryl)-DHPMs as in 51 and 52. Both in situ carbonylations, using different nitrogenand oxygen nucleophiles and direct N-arylations efficiently generated functionalizedamides 53 or esters after only short periods of high-density microwave heating.Additionally, intramolecular seven-membered Heck-endocyclization using Harrmann’sPalladacycle {Pd 2 (Ac) 2 [P(o-tolyl)] 2 } to afford compounds 54 was successfully done undermicrowave irradiations. 50297