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Part-IIResults and DiscussionTable-42. MDR reversal effects of newly synthesized compounds on mdr1-genetransfected mouse lymphoma cell line (l 5178 y) by flow cytometryS.No.Samples µM dye FSC SSC FL-1 FAR1. PAR - R123 506,87 202,17 983,79 - 8582. PAR - R123 499,44 206,08 1232,14 - 13363. MDR - R123 503,98 237,33 13,42 - 11MDR mean 481,13 221,05 11,75 - -4. Verapamil 21,99 R123 512,22 253,01 120,78 10,21 50PeakChCl5. VxvNOCH 3NH4 R123 515,23 239,45 95,88 8,16 41SOCl6. VIxiNOCH 3N4 R123 504,37 223,27 83,29 7,11 35SClOCH 37. VxxivSNNHCl4 R123 543,46 220,40 74,58 6, 34 31OCH 3O8. VxviH 3C NH4 R123 510,49 223,91 14,87 1,26 7NClSNCH 3Cl9. VIxiiH 3C N4 R123 501,91 237,41 93,15 7,92 37NClSON10. VxviiH 3CONH4 R123 498,39 220,06 80,55 6,80 34ClH 3CONCl11. VIxiiiH 3CON4 R123 489,47 227,03 85,44 7,27 35ClH 3CONO12. VviiNHCl4 R123 491,04 213,91 139,86 11,90 60NSONHCl13. VxN4 R123 486,19 222,54 142,10 12, 09 61NS358

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