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3. Ulcer scoreDescription of the descriptors used in the final equation:1. Quadrupole2:Part-IResults and DiscussionThis descriptor signifies magnitude of second tensor of quadrupole moments and isinversely proportional to the activity.2. chiV6chain:This descriptor signifies atomic valence connectivity index for six membered ring and isinversely proportional to the activity.3. T_O_S_3:This is the count of number of oxygen atoms (single double or triple bonded) separatedfrom sulfur atom by 3 bond distance in a molecule and is inversely proportional theactivity.Compound IVxviii has been removed as an outlier from the series. Of these the bestequation was given as under:Ulcer score log(1/C) = - 0.0067(± 0.0000) Quadrupole2 -9.6483(± 1.8345) chiV6chain- 0.1924(± 0.0029) T_O_S_3 + 0.4548….. ………… (Equation-6)n = 15, Degree of freedom = 11, r = 0.9106, r 2 = 0.8292, q 2 = 0.6485, F test = 17.8008,s = 0.1993, t = 2.201 (95%).The resultant equation was evaluated on the basis of good r (coefficient of regression),(r 2 ) coefficient of determination, high cross-validated r 2 for internal productivity and otherstatistical terms like higher F value.The observed and predicted biological activities of the molecules under study are given intable-18.157

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