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Download (4Mb) - Etheses - Saurashtra University

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Part-IExperimentalMol. Formula : C 20 H 16 N 6 O 2 S 2 ; Mol. Wt. 436.5IR (KBr) cm -1 : 2923(γ C-H ), 1678(γ CONH ), 1025(γ S-O ), 756(γ C-S ).35. Synthesis of 6-((5-methoxy-1H-benzo[d]imidazol-2-ylsulfinyl)methyl)-3-(methylthio)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one(IVxxxv)6-((5-Methoxy-1H-benzo[d]imidazol-2-ylthio)methyl)-3-(methylthio)-1-phenyl-1Hpyrazolo[3,4-d]pyrimidin-4(5H)-one(IIIxxxv, 2.4 gm; 0.0054 mole) was dissolved in125 ml methanol and 100 ml dichloromethane by stirring at room temprature. Thereafter,the reaction mixture was chilled in an ice salt bath while maintaining the temperaturebelow 0 o C. To this clear solution, methanolic solution of m-CPBA (1.16 gm; 0.0065mole) was added while stirring and the reation was continued for 30-45 mins. Aftercompletion of the reaction, worked up was done as for the compound IVi.M.P. : 172-175 o C; Yield: 40%Mol. Formula : C 21 H 18 N 6 O 3 S 2 ; Mol. Wt. 466.5IR (KBr) cm -1 : 2980(γ C-H ), 1670(γ CONH ), 1029(γ S-O ), 752(γ C-S ).218

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