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Download (4Mb) - Etheses - Saurashtra University

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Part-IIImpact of Microwave…OO+ NOHH 2 NNHNONNHOHNMWI, 120 o COMWI, 200 o CNNNHONNO29OH 30A methodology for the generation of a microwave-assisted parallel library and itsconversion into a second library was described. A 24-membered library of substituted4(5)-sulfanyl-1H-imidazoles was generated and subsequently converted into a secondlibrary of bicyclic imidazo[5,1-b]thiazol-3-ones and imidazo[5,1-b]-thiazin-4-ones 31.The first library was generated using a multi-component reaction (MCR) and transformedinto a daughter library with a polymer-supported coupling agent. The procedure involvedmicrowave heating without loss of volatile solvents or reagents. Library generation timefor each library was 16 min. 34287

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