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2. Volume of gastric secretion:Description of the descriptors used in the final equation:1. Quadrupole2Part-IResults and DiscussionThis descriptor signifies magnitude of second tensor of quadrupole moments which isdirectly proportional to the activity.2. T_2_O_2This is the count of number of double bounded atoms (i.e. any double bonded atom, T_2)separated from Oxygen atom by 2 bonds in a molecule and is inversely proportional tothe activity.3. chi4pathClusterThis descriptor signifies molecular connectivity index of 4th order pathcluster and isdirectly proportional to the activity.Of these the best equation was given as under:Volume log(1/C) = + 0.0044(± 0.0000) Quadrupole2 - 0.0792(± 0.0121) T_2_O_2+ 0.1385(± 0.0548) chi4pathCluster -2.0199……. (Equation-2)n = 17, Degree of freedom = 13, r = 0.880, r 2 = 0.7752, q 2 = 0.6818, F test = 14.9402, s= 0.0768, t =2.16 (95%).The resultant equation was evaluated on the basis of good r (coefficient of regression),(r 2 ) coefficient of determination, high cross-validated r 2 for internal productivity and otherstatistical terms like higher F-valueThe observed and predicted biological activities of the molecules used in the study aregiven in table-14.151