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Statement Under O.Ph.D. 7 of Saurashtra UniversityThe work included in the thesis is my own work under the supervision of Prof. Kishor S.Jain and Prof. Anamik K. Shah and leads to good contribution in the field ofPharmaceutical Chemistry and is supported by recent references.Date:Place: RajkotJitender Bariwal(M. Pharm)CertificateThis is to certify that the present work submitted for the Ph.D. Degree of SaurashtraUniversity by Mr. Jitender Bariwal has been the result of work carried out under oursupervision and is a good contribution in field of Pharmaceutical Chemistry of“Heterocyclic Compounds” with a special emphasis on synthetic, biological and QSARstudies.Date:Place:Dr. Kishor. S. Jain, (Guide)Principal,Sinhgad College of Pharmacy,Vadgaon (Bk.),Pune-411 041 (India)Prof. Anamik K. Shah, (Co- Guide)Department of Chemistry,Saurashtra University,Rajkot-360005 (India)