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Part-IIImpact of Microwave…N+N21BF 4-OHHOOCDCC, DMAP,dry CH 3 CN,RT, 24 hCHON+NBF 4-O22OCHOORNH 2RRnCat, 2% TFA/CH 3 CN,MWI, 400W, 5 minNaOCH 3 /CH 3 OHRHNOn+HNOnMWI, 400W, 10 minHNOnOO24OOOOBF 4-N+N23A microwave-assisted parallel synthesis of 2,4-disubstituted 5-aminoimidazoles 25 (15compounds) has been developed. Significant rate enhancement was observed for all stepsin the three-step protocol. The overall reaction time was shortened to 25 min, ascompared to 53 hrs for the conventional procedures. 30SSR 1 CN + EtO POEtSHH 2 O, MWI, 80 o C10 minR 1 NH 2BrNH 2. HClCHCl 3 , MWI, 80 o C,10 minR 2NR 1R 2CNR 2 = Ph or COOEtSNH.HBrH 2 N25NHPyridine, CHCl 3 ,MWI, 60 o C, 5 minR 1A methodology for the microwave parallel synthesis of library has been described whichinvolves the use of an array of expandable reaction vessels that can accommodate285