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Part-IResults and DiscussionTable-16: Observed and predicted biological activities of the molecules under study.Compound Observed Predicted ResidualsNo. Activity ActivityIViv -1.835 -1.85122 0.01622IVvi -1.84 -1.85958 0.019576IVviii -1.633 -1.66489 0.031885IVx -1.582 -1.73331 0.151309IVxii -1.822 -1.75702 -0.06498IVxiv -1.761 -1.73812 -0.02288IVxvi -1.75 -1.70894 -0.04106IVxviii -1.786 -1.69871 -0.0873IVxxi -1.678 -1.57946 -0.09854IVxxiii -1.372 -1.50115 0.129148IVxxv -1.709 -1.65017 -0.05883IVxxix -1.709 -1.69189 -0.01711IVxxxi -1.551 -1.56647 0.015468IVxxxiii -1.765 -1.81873 0.053725IVxxxv -1.661 -1.63431 -0.02669Regression analysis of these molecules with the lipophilic parameter, logP has also beencarried out and the equation is given as under; and not very significant.Acidity log(1/C) = - 0.0315(± 0.0403) logP-1.6491n = 16, Degree of freedom = 14, r = 0.2046, r 2 = 0.0419, q 2 = -0.2264, F test = 0.6126.2. Volume of Gastric Secretion:Description of the descriptors used in the final equation:1. SaaNE-index:An Electro topological state index for number of nitrogen atom connected with twoaromatic bonds and is directly proportional to the activity.2. chi3Cluster:This descriptor signifies simple 3rd order cluster chi index in a compound and is inverselyproportional to the activity.3. XcompDipole:This descriptor signifies the x component of the dipole moment (external coordinates) andis directly proportional to the activity.Of these, the best equation was given as under:155

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