Download (4Mb) - Etheses - Saurashtra University

More documents

Recommendations

Info

Part-IIIAdvances Dihydropyridines and …OCH 3OCH 3OCH 3OCH 3OOOOH 3 COOH 3 C N CH 3CH 3H 3 COOH 3 C N CH 3CH 3OO5960OCH 3OCH 3OOH 3 COOH 3 C N CH 3CH 3H 3 COOOCH 3OCH 3NOOH 3 C N CH 3NCH 3OCH 3OCH 3N6162OOH 3 COOH 3 C N CH 3N CH 3CH 363Figure-10. Structures of various N-substituted DHPs (contd.2)414
Part-IIIAdvances Dihydropyridines and …OCH 3OCH 3OOH 3 COOH 3 C N CH 3N64OCH 3OCH 3NOOH 3 COOH 3 C N CH 3N65Figure-10. Structures of various N-substituted DHPs (contd.3)415
Page 1 and 2:
Saurashtra UniversityRe - Accredite
Page 3 and 4:
Statement Under O.Ph.D. 7 of Sauras
Page 5 and 6:
ContentsAcknowledgementRegistration
Page 7 and 8:
Contents1.2 Synthesis of condensed
Page 9 and 10:
Contents1.5 MDR modulators 3981.6 D
Page 11 and 12:
infrastructure and all the faciliti
Page 13 and 14:
Above all I thank Lord Hanuman Ji a
Page 15 and 16:
Abbreviations used1 H NMR Proton Nu
Page 17 and 18:
UVVEGFRWCRWHOZ-EUltra VioletVascula
Page 19 and 20:
22. 2-Substitutedthieno[3,2-d]/benz
Page 21 and 22:
PrefacePrefaceHeterocyclic chemistr
Page 23 and 24:
PrefaceThis entire cascade of react
Page 25 and 26:
PrefaceOONHNHPOCl 3MWINVi-xviiClClC
Page 27 and 28:
PrefaceOOHOOOONHNHDP-7 1NHMonastrol
Page 29 and 30:
PART-I
Page 31 and 32:
3.7 Results and discussion on biolo
Page 33 and 34:
Part-1Review on Antiulcer Literatur
Page 35 and 36:
Page 37 and 38:
Table 2: Distinguishing Features of
Page 39 and 40:
Page 41 and 42:
1.2.2. Muscarinic AntagonistsPart-1
Page 43 and 44:
Page 45 and 46:
Page 47 and 48:
Page 49 and 50:
Page 51 and 52:
Page 53 and 54:
Page 55 and 56:
1.5.5. Pharmacological PropertiesPa
Page 57 and 58:
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
Page 77 and 78:
Page 79 and 80:
Page 81 and 82:
Page 83 and 84:
Page 85 and 86:
Page 87 and 88:
Page 89 and 90:
2. Aim of the Present WorkPart-IAim
Page 91 and 92:
Part-IAim of Present WorkR 2 OR 3 R
Page 93 and 94:
2.2. Bacisity of Pyridine vs Pyrimi
Page 95 and 96:
Part-IAim of Present WorkOANNHOSNHN
Page 97 and 98:
Part-IAim of Present WorkS. No. A S
Page 99 and 100:
3. Results and Discussion
Page 101 and 102:
Part-IResults and Discussion3.1.1d
Page 103 and 104:
Part-IResults and DiscussionOR 1XR
Page 105 and 106:
Part-IResults and Discussionformed
Page 107 and 108:
Part-IResults and DiscussionOOON 2
Page 109 and 110:
c. Synthesis of 2-carbethoxy-3-amin
Page 111 and 112:
Part-IResults and DiscussionTable 7
Page 113 and 114:
Part-IResults and DiscussionOOEtNHO
Page 115 and 116:
Part-IResults and DiscussionTable-8
Page 117 and 118:
Part-IResults and DiscussionCompd.N
Page 119 and 120:
Part-IResults and DiscussionStep-IY
Page 121 and 122:
S. No. Y Mol. Formula(Sol. ofrecrys
Page 123 and 124:
Part-IResults and DiscussionS. No.
Page 125 and 126:
Page 127 and 128:
Part-IResults and DiscussionONNHIII
Page 129 and 130:
Part-IResults and DiscussionS. No.A
Page 131 and 132:
Page 133 and 134:
Page 135 and 136:
Part-IResults and Discussion3.5. Sp
Page 137 and 138:
Specimen 1 H NMR spectra of 2-chlor
Page 139 and 140:
Part-IResults and Discussioninvolve
Page 141 and 142:
Part-IResults and DiscussionSpecime
Page 143 and 144:
The Infrared (IR) spectra:Part-IRes
Page 145 and 146:
Part-IResults and DiscussionR 1ON+
Page 147 and 148:
Part-IResults and DiscussionOSNHOSN
Page 149 and 150:
3.6 Biological Evaluation of PPI’
Page 151 and 152:
Part-IResults and DiscussionExperim
Page 153 and 154:
Part-IResults and DiscussionDrug Pr
Page 155 and 156:
Table 11. Effect of newly synthesiz
Page 157 and 158:
Part-IResults and DiscussionS.No.AR
Page 159 and 160:
Part-IResults and DiscussionS.No.AR
Page 161 and 162:
Figure-1. Effect of newly synthesiz
Page 163 and 164:
Figure-3. Effect of newly synthesiz
Page 165 and 166:
Part-IResults and DiscussionFigure
Page 167 and 168:
Part-IResults and DiscussionFigure
Page 169 and 170:
Part-IResults and Discussion2. Effe
Page 171 and 172:
Part-IResults and Discussionby kine
Page 173 and 174:
Part-IResults and DiscussionNNNNNHN
Page 175 and 176:
3.8. QSAR StudiesPart-IResults and
Page 177 and 178:
Part-IResults and DiscussionFigure-
Page 179 and 180:
Part-IResults and DiscussionPhysico
Page 181 and 182:
Page 183 and 184:
Part-IResults and DiscussionThe MDS
Page 185 and 186:
2. Volume of gastric secretion:Desc
Page 187 and 188:
Part-IResults and DiscussionFor the
Page 189 and 190:
Page 191 and 192:
3. Ulcer scoreDescription of the de
Page 193 and 194:
Page 195 and 196:
Page 197 and 198:
Part-IResults and Discussion24. Ros
Page 199 and 200:
4. Experimental
Page 201 and 202:
Part-IExperimental119 o C was 128-1
Page 203 and 204:
5. Synthesis of ethyl 2-amino-4-phe
Page 205 and 206:
Part-IExperimentalthe procedure des
Page 207 and 208:
Part-IExperimentalRecrystallization
Page 209 and 210:
Part-IExperimentalM.P. : 132-134 o
Page 211 and 212:
Part-IExperimentalA solution of thi
Page 213 and 214:
Part-IExperimentalNMR (CDCl 3 )δpp
Page 215 and 216:
Part-IExperimental6. Reaction of et
Page 217 and 218:
Part-IExperimentalNMR (CDCl 3 )δpp
Page 219 and 220:
Part-IExperimentalM.P. : 240-245 o
Page 221 and 222:
Part-IExperimentalrecrystallization
Page 223 and 224:
Part-IExperimental(1H, d, CH at imi
Page 225 and 226:
Part-IExperimentalNMR (DMSO-d 6 )δ
Page 227 and 228:
M.P. : 140-142 o C; Yield: 73%.Mol.
Page 229 and 230:
M.P. : 135-141 o C; Yield: 67%.Mol.
Page 231 and 232:
Part-IExperimentalml), over a perio
Page 233 and 234:
Part-IExperimentalchloride was adde
Page 235 and 236:
Part-IExperimental29. Synthesis of
Page 237 and 238:
Part-IExperimentalIR (KBr) cm -1 :
Page 239 and 240:
Part-IExperimentaladded while stirr
Page 241 and 242:
Part-IExperimentald]pyrimidin-4(3H)
Page 243 and 244:
Part-IExperimentalMol. formula : C
Page 245 and 246:
Part-IExperimentalthis clear soluti
Page 247 and 248:
Page 249 and 250:
Part-IExperimentalwhile maintaining
Page 251 and 252:
Page 253 and 254:
Part-IExperimentalMol. Formula : C
Page 255 and 256:
PART-II
Page 257 and 258:
Part-IIContents2.3.2.1 Mononuclear
Page 259 and 260:
Part-IISynthesis of Pyrimidines1. S
Page 261 and 262:
Part-IISynthesis of PyrimidinesYZR
Page 263 and 264:
Part-IISynthesis of Pyrimidineselec
Page 265 and 266:
Part-IISynthesis of PyrimidinesR 1R
Page 267 and 268:
Part-IISynthesis of Pyrimidinespyri
Page 269 and 270:
R 1 R 2 R Yield(%)Part-IISynthesis
Page 271 and 272:
Page 273 and 274:
Page 275 and 276:
Part-IISynthesis of Pyrimidinesyiel
Page 277 and 278:
Table 27: 2-Amino-3-substitutedaryl
Page 279 and 280:
Part-IISynthesis of PyrimidinesWhil
Page 281 and 282:
Part-IISynthesis of PyrimidinesSimi
Page 283 and 284:
Part-IISynthesis of PyrimidinesTabl
Page 285 and 286:
R 1 R 2 R X Yield(%)Part-IISynthesi
Page 287 and 288:
Part-IISynthesis of Pyrimidines+RCN
Page 289 and 290:
Part-IISynthesis of PyrimidinesNN+
Page 291 and 292:
Part-IISynthesis of PyrimidinesR 1+
Page 293 and 294:
Part-IISynthesis of Pyrimidinesthe
Page 295 and 296:
Part-IISynthesis of Pyrimidinesacet
Page 297 and 298:
Part-IISynthesis of Pyrimidinesexpe
Page 299 and 300:
Part-IISynthesis of PyrimidinesNOOC
Page 301 and 302:
Part-IISynthesis of PyrimidinesThe
Page 303 and 304:
Part-IISynthesis of PyrimidinesTabl
Page 305 and 306:
Part-IISynthesis of PyrimidinesOH 3
Page 307 and 308:
1.10 ReferencesPart-IISynthesis of
Page 309 and 310:
Part-IISynthesis of Pyrimidines42.
Page 311 and 312:
2. Impact of Microwave Assisted Hea
Page 313 and 314:
Part-IIImpact of Microwave…Microw
Page 315 and 316:
Part-IIImpact of Microwave…Figure
Page 317 and 318:
Part-IIImpact of Microwave…R 1ArR
Page 319 and 320:
Part-IIImpact of Microwave…as an
Page 321 and 322:
Part-IIImpact of Microwave…al. 21
Page 323 and 324:
Part-IIImpact of Microwave…XOHR 1
Page 325 and 326:
Part-IIImpact of Microwave…N+N21B
Page 327 and 328:
Part-IIImpact of Microwave…OO+ NO
Page 329 and 330:
Part-IIImpact of Microwave…NO 2NO
Page 331 and 332:
Part-IIImpact of Microwave…RNHNNH
Page 333 and 334:
Part-IIImpact of Microwave…assist
Page 335 and 336:
Part-IIImpact of Microwave…CNRNH
Page 337 and 338:
Part-IIImpact of Microwave…Multig
Page 339 and 340:
Part-IIImpact of Microwave…Nie et
Page 341 and 342:
Part-IIImpact of Microwave…synthe
Page 343 and 344:
Part-IIImpact of Microwave…An eff
Page 345 and 346:
Part-IIImpact of Microwave…OO+S 8
Page 347 and 348:
2.6. ReferencesPart-IIImpact of Mic
Page 349 and 350:
49. Baxendale, I. R.; Ley, S. V. J.
Page 351 and 352:
Part-IIAim of the Present Work3. Ai
Page 353 and 354:
Part-IIAim of the Present WorkONHR
Page 355 and 356:
Part-IIAim of the Present WorkYZXNN
Page 357 and 358:
Part-IIAim of the Present WorkThe c
Page 359 and 360:
3.5 References:Part-IIAim of the Pr
Page 361 and 362:
Part-IIAim of the Present Work37. S
Page 363 and 364:
Part-IIResults and Discussion4.1 Sy
Page 365 and 366:
4.2 Synthesis of condensed 2-substi
Page 367 and 368:
Table 38: Physical data of condense
Page 369 and 370:
S. No. X Time ofMWIHeating(Min)VxiV
Page 371 and 372:
S. No. X Time ofMWIHeating(Min)Yiel
Page 373 and 374:
4.3 Synthesis of condensed 4-chloro
Page 375 and 376:
Part-IIResults and DiscussionHerein
Page 377 and 378:
Part-IIResults and DiscussionS. No.
Page 379 and 380:
Part-IIResults and DiscussionS. No.
Page 381 and 382:
The Mass spectraPart-IIResults and
Page 383 and 384:
Specimen IR spectra of some 2-chlor
Page 385 and 386:
Page 387 and 388:
Part-IIResults and Discussion1 H NM
Page 389 and 390:
Part-IIResults and Discussionion (c
Page 391 and 392:
Page 393 and 394:
Specimen 1 H NMR spectra of 4-chlor
Page 395 and 396:
Part-IIResults and Discussion4.5 MD
Page 397 and 398:
Part-IIResults and DiscussionH 3CO1
Page 399 and 400:
Part-IIResults and DiscussionCl14.
Page 401 and 402:
Part-IIResults and DiscussionO14. V
Page 403 and 404:
4.6 References:Part-IIResults and D
Page 405 and 406:
5. ExperimentalPart-IIExperimentalA
Page 407 and 408:
3. Synthesis of 2-chloromethyl-5-ph
Page 409 and 410: Part-IIExperimentalIR (KBr) cm -1 :
Page 411 and 412: Part-IIExperimentalM.P. : 247-249 o
Page 413 and 414: Part-IIExperimental5.4 Synthesis of
Page 415 and 416: Part-IIExperimentalwere reacted und
Page 417 and 418: 27. Synthesis of 2-methyl-5-phenylt
Page 419 and 420: Part-IIExperimental80 o C) that yie
Page 421 and 422: Part-IIExperimental36. Synthesis of
Page 423 and 424: Part-IIExperimentalunder microwave
Page 425 and 426: Part-IIExperimentalM.P. : >300 o C
Page 427 and 428: M.P. : 280-282 o C; Yield: 90%Mol.
Page 429 and 430: 5.10 References:Part-IIExperimental
Page 431 and 432: Synthesis, Characterization and Ant
Page 433 and 434: Part-IIIAdvances Dihydropyridines a
Page 455 and 456: CH 3CH 3Part-IIIAdvances Dihydropyr
Page 459: Part-IIIAdvances Dihydropyridines a
Page 497 and 498: 2. Aim of the Present Work
Page 499 and 500: Part-IIIAim of the Present Workshor
Page 501 and 502: 3. Results and Discussion
Page 503 and 504: Part-IIIResults and DiscussionOOOHR
Page 505 and 506: Part-IIIResults and DiscussionUsing
Page 507 and 508: Part-IIIResults and DiscussionS. No
Page 509 and 510: S. No R X MolFormula(Sol. of Recrys
Page 511 and 512:
Part-IIIResults and Discussionpheny
Page 513 and 514:
Specimen 13 C NMR spectra of some D
Page 515 and 516:
Part-IIIResults and DiscussionTable
Page 517 and 518:
Part-IIIResults and DiscussionTable
Page 519 and 520:
3.5 DiscussionPart-IIIResults and D
Page 521 and 522:
4. Experimental
Page 523 and 524:
Part-IIIExperimentalglacial acetic
Page 525 and 526:
Part-IIIExperimental5. Synthesis of
Page 527 and 528:
Part-IIIExperimentalIR(KBr) cm -1 :
Page 529 and 530:
Part-IIIExperimentalM.P. : 184-186
Page 531 and 532:
Part-IIIExperimental1 H NMR(DMSO-d
Page 533 and 534:
Part-IIIExperimentalM.P. : 188-190
Page 535 and 536:
Part-IIIExperimental4.2 MDR reversa
Page 537 and 538:
Summary and Conclusion
Page 539 and 540:
Summary and Conclusionactivity in P
Page 541 and 542:
Summary and Conclusionreverting act
Page 543 and 544:
Publications and Presentations
Page 545 and 546:
Publications and PresentationsOther
Page 547:
Publications and Presentations8. K.
show all

Download (4Mb) - Etheses - Saurashtra University

Create successful ePaper yourself

Delete template?

Save as template?