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3.7 Results and discussion on biological activity and mechanism of action ofthe newly synthesized compoundsPart-IContents3.8 QSAR studies 1413.9 References 1624. Experimental 1654.1 Synthesis of starting materials 1654.1.1 Synthesis of chloroacetonitrile 1654.1.2 Synthesis of thiophene o-aminoesters (Ii-xii) 1664.2 Synthesis of starting materials (Ixiii-xvii) of other condensed pyrimidines 1714.3 Synthesis of condensed 2-chloromethylthieno[2,3-d]pyrimidin-4(3H)-ones (IIi-xviii)4.4 Condensation of the condensed 2-chloromethylthieno[2,3-d]-pyrimidin-4(3H)-ones (IIi-xviii) with 2-mercaptobenzimidazoles (IIIi-xxxv)4.5 Oxidation of condensed 2-(1H-benzimidazol-2-yl)methylthio-pyrimidin-4(3H)-ones using meta-chloroperbenzoic acid (m-CPBA) to obtaincorresponding sulfinyl derivatives (IVi-xxxv)4.6 References 219134177185203