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Figure-2. Effect of newly synthesized compounds on total acidity of gastric secretion in Shay rat model80706050403020100128Part-IResults and DiscussionControlOmeprazoleIViIViiIViiiIVivIVvIVviIVviiIVviiiIVixIVxIVxiIVxiiIVxiiiIVxivIVxvIVxviIVxviiIVxviiiIVxixIVxxIVxxiIVxxiiIVxxiiiIVxxivIVxxvTotal Acidity (mEq/100gm)IVxxviiiIVxxixIVxxxIVxxxiIVxxxiiIVxxxiiiIVxxxivIVxxxvTreatment Groups
Figure-3. Effect of newly synthesized compounds on total volume of gastric secretion in Shay rat model14121086420129Part-IResults and DiscussionControlOmeprazoleIViIViiIViiiIVivIVvIVviIVviiIVviiiIVixIVxIVxiIVxiiIVxiiiIVxivIVxvIVxviIVxviiIVxviiiIVxixIVxxIVxxiIVxxiiIVxxiiiIVxxivIVxxvVol. of Gastric Juice (ml)IVxxviiiIVxxixIVxxxIVxxxiIVxxxiiIVxxxiiiIVxxxivIVxxxvTreatment Groups
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Saurashtra UniversityRe - Accredite
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Statement Under O.Ph.D. 7 of Sauras
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ContentsAcknowledgementRegistration
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Contents1.2 Synthesis of condensed
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Contents1.5 MDR modulators 3981.6 D
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infrastructure and all the faciliti
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Above all I thank Lord Hanuman Ji a
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Abbreviations used1 H NMR Proton Nu
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UVVEGFRWCRWHOZ-EUltra VioletVascula
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22. 2-Substitutedthieno[3,2-d]/benz
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PrefacePrefaceHeterocyclic chemistr
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PrefaceThis entire cascade of react
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PrefaceOONHNHPOCl 3MWINVi-xviiClClC
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PrefaceOOHOOOONHNHDP-7 1NHMonastrol
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PART-I
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3.7 Results and discussion on biolo
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Part-1Review on Antiulcer Literatur
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Table 2: Distinguishing Features of
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1.2.2. Muscarinic AntagonistsPart-1
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1.5.5. Pharmacological PropertiesPa
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2. Aim of the Present WorkPart-IAim
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Part-IAim of Present WorkR 2 OR 3 R
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2.2. Bacisity of Pyridine vs Pyrimi
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Part-IAim of Present WorkOANNHOSNHN
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Part-IAim of Present WorkS. No. A S
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3. Results and Discussion
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Part-IResults and Discussion3.1.1d
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Part-IResults and DiscussionOR 1XR
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Part-IResults and Discussionformed
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Part-IResults and DiscussionOOON 2
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c. Synthesis of 2-carbethoxy-3-amin
Page 111 and 112: Part-IResults and DiscussionTable 7
Page 113 and 114: Part-IResults and DiscussionOOEtNHO
Page 115 and 116: Part-IResults and DiscussionTable-8
Page 117 and 118: Part-IResults and DiscussionCompd.N
Page 119 and 120: Part-IResults and DiscussionStep-IY
Page 121 and 122: S. No. Y Mol. Formula(Sol. ofrecrys
Page 123 and 124: Part-IResults and DiscussionS. No.
Page 127 and 128: Part-IResults and DiscussionONNHIII
Page 129 and 130: Part-IResults and DiscussionS. No.A
Page 135 and 136: Part-IResults and Discussion3.5. Sp
Page 137 and 138: Specimen 1 H NMR spectra of 2-chlor
Page 139 and 140: Part-IResults and Discussioninvolve
Page 141 and 142: Part-IResults and DiscussionSpecime
Page 143 and 144: The Infrared (IR) spectra:Part-IRes
Page 145 and 146: Part-IResults and DiscussionR 1ON+
Page 147 and 148: Part-IResults and DiscussionOSNHOSN
Page 149 and 150: 3.6 Biological Evaluation of PPI’
Page 151 and 152: Part-IResults and DiscussionExperim
Page 153 and 154: Part-IResults and DiscussionDrug Pr
Page 155 and 156: Table 11. Effect of newly synthesiz
Page 157 and 158: Part-IResults and DiscussionS.No.AR
Page 159 and 160: Part-IResults and DiscussionS.No.AR
Page 161: Figure-1. Effect of newly synthesiz
Page 165 and 166: Part-IResults and DiscussionFigure
Page 167 and 168: Part-IResults and DiscussionFigure
Page 169 and 170: Part-IResults and Discussion2. Effe
Page 171 and 172: Part-IResults and Discussionby kine
Page 173 and 174: Part-IResults and DiscussionNNNNNHN
Page 175 and 176: 3.8. QSAR StudiesPart-IResults and
Page 177 and 178: Part-IResults and DiscussionFigure-
Page 179 and 180: Part-IResults and DiscussionPhysico
Page 183 and 184: Part-IResults and DiscussionThe MDS
Page 185 and 186: 2. Volume of gastric secretion:Desc
Page 187 and 188: Part-IResults and DiscussionFor the
Page 191 and 192: 3. Ulcer scoreDescription of the de
Page 197 and 198: Part-IResults and Discussion24. Ros
Page 199 and 200: 4. Experimental
Page 201 and 202: Part-IExperimental119 o C was 128-1
Page 203 and 204: 5. Synthesis of ethyl 2-amino-4-phe
Page 205 and 206: Part-IExperimentalthe procedure des
Page 207 and 208: Part-IExperimentalRecrystallization
Page 209 and 210: Part-IExperimentalM.P. : 132-134 o
Page 211 and 212: Part-IExperimentalA solution of thi
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Part-IExperimentalNMR (CDCl 3 )δpp
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Part-IExperimental6. Reaction of et
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Part-IExperimentalNMR (CDCl 3 )δpp
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Part-IExperimentalM.P. : 240-245 o
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Part-IExperimentalrecrystallization
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Part-IExperimental(1H, d, CH at imi
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Part-IExperimentalNMR (DMSO-d 6 )δ
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M.P. : 140-142 o C; Yield: 73%.Mol.
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M.P. : 135-141 o C; Yield: 67%.Mol.
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Part-IExperimentalml), over a perio
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Part-IExperimentalchloride was adde
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Part-IExperimental29. Synthesis of
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Part-IExperimentalIR (KBr) cm -1 :
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Part-IExperimentaladded while stirr
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Part-IExperimentald]pyrimidin-4(3H)
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Part-IExperimentalMol. formula : C
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Part-IExperimentalthis clear soluti
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Part-IExperimentalwhile maintaining
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Part-IExperimentalMol. Formula : C
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PART-II
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Part-IIContents2.3.2.1 Mononuclear
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Part-IISynthesis of Pyrimidines1. S
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Part-IISynthesis of PyrimidinesYZR
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Part-IISynthesis of Pyrimidineselec
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Part-IISynthesis of PyrimidinesR 1R
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Part-IISynthesis of Pyrimidinespyri
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R 1 R 2 R Yield(%)Part-IISynthesis
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Part-IISynthesis of Pyrimidinesyiel
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Table 27: 2-Amino-3-substitutedaryl
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Part-IISynthesis of PyrimidinesWhil
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Part-IISynthesis of PyrimidinesSimi
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Part-IISynthesis of PyrimidinesTabl
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R 1 R 2 R X Yield(%)Part-IISynthesi
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Part-IISynthesis of Pyrimidines+RCN
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Part-IISynthesis of PyrimidinesNN+
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Part-IISynthesis of PyrimidinesR 1+
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Part-IISynthesis of Pyrimidinesthe
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Part-IISynthesis of Pyrimidinesacet
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Part-IISynthesis of Pyrimidinesexpe
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Part-IISynthesis of PyrimidinesNOOC
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Part-IISynthesis of PyrimidinesThe
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Part-IISynthesis of PyrimidinesTabl
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Part-IISynthesis of PyrimidinesOH 3
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1.10 ReferencesPart-IISynthesis of
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Part-IISynthesis of Pyrimidines42.
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2. Impact of Microwave Assisted Hea
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Part-IIImpact of Microwave…Microw
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Part-IIImpact of Microwave…Figure
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Part-IIImpact of Microwave…R 1ArR
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Part-IIImpact of Microwave…as an
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Part-IIImpact of Microwave…al. 21
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Part-IIImpact of Microwave…XOHR 1
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Part-IIImpact of Microwave…N+N21B
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Part-IIImpact of Microwave…OO+ NO
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Part-IIImpact of Microwave…NO 2NO
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Part-IIImpact of Microwave…RNHNNH
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Part-IIImpact of Microwave…assist
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Part-IIImpact of Microwave…CNRNH
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Part-IIImpact of Microwave…Multig
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Part-IIImpact of Microwave…Nie et
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Part-IIImpact of Microwave…synthe
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Part-IIImpact of Microwave…An eff
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Part-IIImpact of Microwave…OO+S 8
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2.6. ReferencesPart-IIImpact of Mic
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49. Baxendale, I. R.; Ley, S. V. J.
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Part-IIAim of the Present Work3. Ai
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Part-IIAim of the Present WorkONHR
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Part-IIAim of the Present WorkYZXNN
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Part-IIAim of the Present WorkThe c
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3.5 References:Part-IIAim of the Pr
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Part-IIAim of the Present Work37. S
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Part-IIResults and Discussion4.1 Sy
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4.2 Synthesis of condensed 2-substi
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Table 38: Physical data of condense
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S. No. X Time ofMWIHeating(Min)VxiV
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S. No. X Time ofMWIHeating(Min)Yiel
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4.3 Synthesis of condensed 4-chloro
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Part-IIResults and DiscussionHerein
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Part-IIResults and DiscussionS. No.
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Part-IIResults and DiscussionS. No.
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The Mass spectraPart-IIResults and
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Specimen IR spectra of some 2-chlor
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Part-IIResults and Discussion1 H NM
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Part-IIResults and Discussionion (c
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Specimen 1 H NMR spectra of 4-chlor
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Part-IIResults and Discussion4.5 MD
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Part-IIResults and DiscussionH 3CO1
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Part-IIResults and DiscussionCl14.
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Part-IIResults and DiscussionO14. V
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4.6 References:Part-IIResults and D
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5. ExperimentalPart-IIExperimentalA
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3. Synthesis of 2-chloromethyl-5-ph
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Part-IIExperimentalIR (KBr) cm -1 :
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Part-IIExperimentalM.P. : 247-249 o
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Part-IIExperimental5.4 Synthesis of
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Part-IIExperimentalwere reacted und
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27. Synthesis of 2-methyl-5-phenylt
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Part-IIExperimental80 o C) that yie
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Part-IIExperimental36. Synthesis of
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Part-IIExperimentalunder microwave
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Part-IIExperimentalM.P. : >300 o C
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M.P. : 280-282 o C; Yield: 90%Mol.
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5.10 References:Part-IIExperimental
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Synthesis, Characterization and Ant
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Part-IIIAdvances Dihydropyridines a
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CH 3CH 3Part-IIIAdvances Dihydropyr
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2. Aim of the Present Work
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Part-IIIAim of the Present Workshor
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3. Results and Discussion
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Part-IIIResults and DiscussionOOOHR
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Part-IIIResults and DiscussionUsing
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Part-IIIResults and DiscussionS. No
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S. No R X MolFormula(Sol. of Recrys
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Part-IIIResults and Discussionpheny
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Specimen 13 C NMR spectra of some D
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Part-IIIResults and DiscussionTable
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Part-IIIResults and DiscussionTable
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3.5 DiscussionPart-IIIResults and D
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4. Experimental
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Part-IIIExperimentalglacial acetic
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Part-IIIExperimental5. Synthesis of
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Part-IIIExperimentalIR(KBr) cm -1 :
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Part-IIIExperimentalM.P. : 184-186
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Part-IIIExperimental1 H NMR(DMSO-d
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Part-IIIExperimentalM.P. : 188-190
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Part-IIIExperimental4.2 MDR reversa
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Summary and Conclusion
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Summary and Conclusionactivity in P
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Summary and Conclusionreverting act
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Publications and Presentations
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Publications and PresentationsOther
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Publications and Presentations8. K.
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