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Part-IISynthesis of Pyrimidines2-Substitutedbenzothieno[3,2-d]pyrimidin-4(3H)-ones, 2-Substitutedpyridothieno[3,2-d]-pyrimidin-4(3H)-ones (Table 3) and 2-Substitutedbenzofurano[3,2-d]pyrimidin-4(3H)-ones (Table 23)Table 22: 2-Substitutedthieno[3,2-d]/benzo(b)thieno[3,2-d]/pyridothieno[3,2-d]-pyrimidin-4(3H)-ones.R 1R 1NR+ RCNNH 2R 2 COOC 2 H 5Sdry HClR 2SONHR 1 R 2 R Yield R. Solv. Reference(%)C 6 H 5 H -CH 3 80 C 42C 6 H 5 H -CH 2 Cl 82 E 42C 6 H 5 H -CH 2 CH 2 Cl 76 C 42C 6 H 5 H -C 6 H 5 63 D 43C 6 H 5 H -SH 54 D-E 43H C 6 H 5 -CH 3 45 E-C 42H C 6 H 5 -CH 2 Cl 40 E-C 42H C 6 H 5 -CO 2 C 2 H 5 25 E-C 42H C 6 H 5 -CH 2 CO 2 C 2 H 5 38 C-P 42H C 6 H 5 -CH 2 CH 2 Cl 41 E-C 42H C 6 H 5 -C 6 H 5 35 E-C 42H C 6 H 5 -CH 2 C 6 H 5 32 E-C 42H C 6 H 5 -CH 2 C 6 H 4 Cl-4 38 C-P 42H C 6 H 5 -CH 2 C 6 H 4 NO 2 -4 52 C-P 42H C 6 H 5 -CH 2 =CH-C 6 H 5 55 E-C 42-CH=CH-CH=CH- -CH 3 73 E-D 28, 35-CH=CH-CH=CH- -CH 2 C 6 H 5 69 E-D 28-CH=CH-CH=CH- -CH 2 Cl 63 E-D 35-CH=CH-CH=CH- -CH 2 CO 2 C 2 H 5 66 E-D 31-C(OCH 3 )=CH-CH=CH- -CH 2 C 6 H 5 65 E-D 28-C(OCH 3 )=CH-CH=CH- -CH 2 CO 2 C 2 H 5 58 E-D 31-C(CH 3 )=CH-C(CH 3 )=N- -CH 3 62 E-C 35-C(CH 3 )=CH-C(CH 3 )=N- -CH 2 Cl 68 E 35-C(CH 3 )=CH-C(CH 3 )=N- -CH 2 OCH 3 62 D 44-C(CH 3 )=CH-C(CH 3 )=N- -CH 2 OC 2 H 5 64 E-C 44233