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Download (4Mb) - Etheses - Saurashtra University

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Part-IIIExperimentalM.P. : 240-242 o C; Yield 66%.Mol. Formula : C 18 H 14 Br 2 N 2 O 3 ; Mol. Wt. 466.12IR(KBr) cm -1 : 3383(γ NH ), 2955(γ CH ), 1712(γ CO ), 1689(γ CONH ).14. Synthesis of 5-benzoyl-4-(3,4-dimethoxyphenyl)-6-methyl-3,4-dihydro-pyrimidin-2(1H)-one from benzoylacetone (VIIxiv)A mixture of benzoylacetone (0.0072 mole; 1.1 gm), 3,4-dimethoxybenzaldehyde (0.0060mole; 1 gm) and urea (0.009 mole; 0.54 gm) in ethanol (10 ml) were reacted as perprocedure for the compound (VIIi) to get 5-benzoyl-6-methyl-4-(3,4-dimethoxyphenyl)-3,4-dihydropyrimidin-2(1H)-one (VIIxiv).M.P. : 234-236 o C; Yield 77%.Mol. Formula : C 20 H 20 N 2 O 4 ; Mol. Wt. 352.38IR(KBr) cm -1 : 3372(γ NH ), 1656(γ CONH ).15. Synthesis of 5-benzoyl-4-(3-bromophenyl)-6-methyl-3,4-dihydropyrimidin-2(1H)-one (VIIxv) from benzoylacetoneA mixture of benzoylacetone (0.0064 mole; 1.05 gm), 3-bromobenzaldehyde (0.0054mole; 1 gm) and urea (0.0081 mole; 0.48 gm) in ethanol (10 ml) were reacted as perprocedure for the compound (VIIi) to get 5-benzoyl-6-methyl-4-(3-bromophenyl)-3,4-dihydropyrimidin-2(1H)-one (VIIxv).M.P. : 218-220 o C; Yield 69%.Mol. Formula : C 18 H 15 BrN 2 O 2 ; Mol. Wt. 371.23IR(KBr) cm -1 : 3290(γ NH ), 2946(γ CH ), 1708(γ CO ), 1673(γ CONH ).16. Synthesis of 5-benzoyl-6-methyl-4-[(E)-2-phenylvinyl]-3,4-dihydropyrimidin-2(1H)-one (VIIxvi) from benzoylacetoneA mixture of benzoylacetone (0.0090 mole; 1.47 gm), cinnamaldehyde (0.0075 mole; 1gm) and urea (0.0112 mole; 0.67 gm) in ethanol (10 ml) were reacted as per procedure forthe compound (VIIi) to get 5-benzoyl-6-methyl-4-[(E)-2-phenylvinyl]-3,4-dihydropyrimidin-2(1H)-one (VIIxvi).479

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