Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

Fluids Hypertension Syndromes – Dr. Leonardo Izecksohn – page 191
Although the etiologies are the same and can happen together, some of these toxic retinal and
choroidal vascular leaks do not belong to the Cerebrospinal Fluid Hypertension Syndrome.
The fluids hypertension affect the toxic retinal and choroidal vascular leakage inside the eye by two
opposite ways:
A- Reducing the exudation: The Ocular Hypertension reduces or impedes the exudation and the damage
inside the eye, because the raised intraocular pressure acts on contrary to the exudation pressure.
B- Increasing the exudation: The Cerebrospinal Fluid Hypertension increases the exudation and all
the damage, because it stretches the Central Retinal vein (explained above), increases the venous blood
pressure inside it, and this increases the exudation pressure in the retina, inside the eye.
The arterial hypertension also increases these exudates, hemorrhages and damage, because it increases
the arterial perfusion pressure inside the arterial capillaries in the eye.
Smoking also increases the occurrence and progression of the “Age-related macular degeneration”:
“People in Beaver Dam, Wisconsin, who were aged 43 to 84 years… who were current smokers at
baseline, compared with those who never smoked, were at increased risk of incident early age-related
macular degeneration and for progression of age-related macular degeneration during a 15-year followup.”
(Klein R, and others).
Is smoking intoxicating alone, or is it increasing the coffee consumption, and the main toxin is the
caffeine?
Central Serous Chorioretinopathy caused by caffeinated soft drinks: We had a 32-year-old mulatto
(Indian, black and white ancestors), 1,61 meter, 62 Kilograms (136 pounds), strong workman, one
wife, four children. He began drinking 1.500 milliliter of cachaça (distilled alcohol 50% or more)
daily with 17 year-old; some days he did not eat anything, and on one occasion he past 22 continual
days without food, with only cachaça drinks. He stopped drinking cachaça when his liver began to become
sick, with 24 year-old. Immediately, he began to drink coffee 500 milliliter, added with 3.000 milliliter
of cola soft drinks daily, until now, without interruption, for 8 years. During this period, he felt
daily plenty sneezes with nasal obstruction and profuse coryza, with the maximum of two days of continuous
duration, which forced him on working time, to use a handkerchief over the left shoulder in order
to dry his nose only with turning his head without using his hands. Around on ten different occasions,
he presented hard dizziness at awakening that endured the entire day, which made him impossible
to walk or getting out of house to work. Two months ago, he presented blurring of the left eye
central vision, without any other sign or symptom. On the examination, we found the intraocular pressures
11 and 12 mmHg right and left eyes, which are physiologic. On direct ophthalmoscopy, we found
signs of moderate spread arteriosclerosis with compression of the crossing arteries over the veins, and
a Central Serous Chorioretinopathy in his left eye. All of the above sicknesses, signs and symptoms
were consequent to the Cerebrospinal Fluid Hypertension Syndrome, caused by the caffeine.
The Cerebrospinal Fluid Hypertension can cause retinal ischemia, exudation and hemorrhages in the
retina and under it, by the many ways above described. When many times relapsing the exudation,
hemorrhages and their resorption, they become fibrosis and more ischemia, which causes liberation of
Vascular Endothelial Grow Factor (VEGF), which causes neovascularization, more exudation and hemorrhages,
and finally retinal degeneration and blindness. The retinal pigment epithelium and choroid
degeneration have many denominations, as Age-related Macular degeneration, Geographic atrophy, and
others.
“These data suggest a relationship between beer consumption and greater odds of having exudative
macular degeneration, and increased retinal pigment degeneration”. (Ritter L L, and others). The beer is
a strong etiology to the Cerebrospinal Fluid Hypertension (see Etiologies).