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Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

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<strong>Fluids</strong> <strong>Hypertension</strong> <strong>Syndromes</strong> – Dr. Leonardo Izecksohn – page 283<br />

epicatechin 3-gallate from 203 to 471 mg/l,<br />

epigallocatechin from 16.9 to 150 mg/l,<br />

epicatechin from 25 to 81 mg/l and<br />

catechin from 9.03 to 115 mg/l.<br />

Caffeine contents in the green tea infusions studied were between 141-338 mg/l.” (Reto M, and<br />

others).<br />

XVII- 1 - Blood pressure reduction: “In spontaneously hypertensive rats... we found that intraduodenal<br />

injection of decaffeinated oolong tea lowered renal sympathetic nerve activity and blood pressure<br />

as well as oolong tea, indicating that substances other than caffeine contained in oolong tea may<br />

function as effective modulators of renal sympathetic nerve activity and blood pressure.” (Tanida M,<br />

and others).<br />

XVII- 2 - Cutaneous type-I allergic reaction: “Three tea catechins, epigallocatechin, epicatechin gallate,<br />

and epigallocatechin gallate showed inhibitory effects on the passive cutaneous type-I allergic reaction<br />

of rat after oral administration. The inhibitory effects of epigallocatechin and epigallocatechin<br />

gallate on the passive cutaneous anaphylaxis reaction were greater than that of epicatechin gallate. Caffeine<br />

also showed a inhibitory effect on the passive cutaneous anaphylaxis reaction.” (Shiozaki T, and<br />

others).<br />

XVII- 3 -Diabetes type 2 risk reduction: “The finding that higher consumption of decaffeinated coffee<br />

was associated with a lower risk of type 2 diabetes suggests that coffee constituents other than caffeine<br />

play a role. Coffee is a source of several compounds that improved glucose metabolism in animal<br />

studies, including the chlorogenic acids and lignans.” (van Dam R M).<br />

Between “28 812 postmenopausal women free of diabetes and cardiovascular disease”, “coffee intake,<br />

especially decaffeinated, was inversely associated with risk of type 2 diabetes mellitus in this cohort of<br />

postmenopausal women.” (Pereira M A, and others).<br />

“Black, green, and oolong teas ... were all shown to increase insulin activity. .. The majority of the<br />

insulin-potentiating activity for green and oolong teas was due to epigallocatechin gallate. For black<br />

tea, the activity was present ... in addition to epigallocatechin gallate, tannins, theaflavins, and other undefined<br />

compounds.” (Anderson A, and Polansky M M).<br />

XVII- 4 -Endothelial function improvement: “In the hour following the ingestion of two cups of decaffeinated<br />

coffee, brachial artery flow-mediated dilation increased (mean+/-s.e.m.): 0 min, 7.4+/-<br />

0.7%; 30 min, 8.0+/-0.6%; 60 min, 10.8+/-0.8% as compared to consumption of one cup of decaffeinated<br />

coffee: 0 min, 6.9+/-0.7%; 30 min, 8.4+/-1.2%; 60 min, 8.5+/-1.1%. Blood pressure did not differ<br />

between groups, and basal heart rate was lower in the two-cup group at baseline and 60 min. Conclusions:The<br />

present study demonstrated a significant acute favorable dose-dependent effect of decaffeinated<br />

espresso coffee on endothelial function.” (Buscemi S, and others).<br />

XVII- 5 -Hearing threshold in diabetic neuropathy: In diabetic mice, “Coffee or trigonelline ameliorated<br />

the hearing threshold shift and delayed latency of the auditory evoked potential in diabetic<br />

neuropathy. These findings demonstrate that ... coffee consumption potentially facilitates recovery from<br />

diabetes-induced auditory neuropathy. Furthermore, the active constituent in coffee may be trigonelline.”<br />

(Hong B N, and others).

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