Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

Fluids Hypertension Syndromes – Dr. Leonardo Izecksohn – page 205
Glaucoma (from the Ocular Hypertension) frequently occurs together with the Cerebrospinal Fluid
Hypertension. Therefore, the chronic Cerebrospinal Fluid Hypertension may be the cause of the
Alzheimer’s disease.
3 - Amyotrophic Lateral Sclerosis (Lou Gehrig disease): We suspect, but we cannot prove that the
Cerebrospinal Fluid Hypertension or caffeine has something with the etiology of this disease. Here is
one patient:
- Aches from Repetitive Motion Injuries and Migraines caused by caffeine and excessive water
(and Amyotrophic Lateral Sclerosis?): We had a 20-year-old miss, 1.63 meters (5 feet and 4 inches)
tall, 65 Kilograms (143 pounds) of weight, with Black father, and Black, Indian and White mother’s ancestors.
She was complaining of headaches on her occipital, bi-temporal and head’s top areas, numbness
and formicating at her left hand, infertility and miscarriages. She was a web designer, and one
physician diagnosed her hand’s symptoms as Repetitive Motion Injuries. She smokes 40 cigarettes,
drinks coffee 500 milliliter (more than a pint) and strong tea “Chimarrão” 5,000 milliliter (nearly one
and a half gallons) daily. She referred that her mother also smoked 40 cigarettes each day and drank
coffee 1,000 milliliter (33 fluid ounces) daily, for around 40 years. The mother suffered variegated
muscles paralysis diagnosed and medicated as Amyotrophic Lateral Sclerosis, and died from a consequence
of this sickness.
On the ophthalmological examination of the daughter we found Optic Nerve’s disks with 0.1/1/0/0.5
and 0/0/0/0.5 (Cup’s diameter/ cup depth/ lamina Cribosa’s pores visibility/ borders edema) right and
left eyes, which characterizes the Cerebrospinal Fluid Hypertension Syndrome. The caffeine etiology of
her sicknesses is evident. As the heredity is a strong factor for these sicknesses, and as the mother and
the daughter both drank too much caffeine, are the daughter’s sicknesses the antecedent of her mother
Amyotrophic Lateral Sclerosis?
4 - Brain disturbs:
“We investigated 35 patients suffering from migraine and … we found a significant decrease of grey
matter in areas ascribable to the transmission of pain (cingulate cortex).” (Schmidt-Wilcke T, and others).
“Migraineurs had on average thicker somatosensory cortex than the control group. The most significant
thickness changes were noticed in the caudal somatosensory cortex, where the trigeminal area, including
head and face, is somatotopically represented. Repetitive migraine attacks may lead to, or be
the result of, neuroplastic changes in cortical and subcortical structures of the trigeminal somatosensory
system.” (DaSilva A F, and others).
“Caffeine increases energy metabolism throughout the brain but decreases at the same time cerebral
blood flow, inducing a relative brain hypoperfusion.” (Nehlig A, and others).
“The protein s100b indicates astrocytal damage as well as dysfunction of the blood-brain barrier. Recently,
s100b was shown to be a potentially useful marker for migraine in children. During migraine attacks
(in 21 migraineurs) elevated s100b levels could be observed. Maximal concentrations were detected
in the pain-free period after 2-4 days. Our data suggest a prolonged disruption of blood-brain barrier
during and after migraine attacks.” (Teepker M, and others).
5 - Brain infarcts (strokes), white and gray matter damage (lesions): The Cerebrospinal Fluid Hypertension
squeezes the Brain, Cerebellum and Spine. Whether this pressure overpasses the arterial perfusion
pressure, it can cause ischemic stroke. It is the brain equivalent to the NAION on the Optic
Nerves.
On 161 patients with migraine with aura, and 134 patients with migraine without aura, all Dutch
adults aged 30 to 60 years, “In the cerebellar region of the posterior circulation territory, patients with
migraine had a higher prevalence of infarct than controls (5.4% vs 0.7%). The highest risk was in patients
with migraine with aura with 1 attack or more per month.” “Among women, the risk for high
deep white matter damage load was increased in patients with migraine.” “These population-based
findings suggest that some patients with migraine with and without aura are at increased risk for subclinical
damage in certain brain areas.” (Kruit M C and others).