Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

Fluids Hypertension Syndromes – Dr. Leonardo Izecksohn – page 231
As caffeine causes or worsens most of the psychiatric morbidities above, and as the Attention-Deficit
Hyperactivity Disorder is congenital, we suspect that the daily caffeine drank by the pregnant mother
causes this brain damage in her baby.
XVI - 23) Axillary Hyperhidrosis: “Since hyperhidrosis of all kinds can be exacerbated by stimulantcontaining
foods, especially caffeine and theobromine, dietary restriction of coffee, tea, cola soft
drinks, and chocolate may improve mild cases of hyperhidrosis.” (Karpinski R H S).
XVI - 24) Behavioral disturbs: “In 132 children 12-24 months of age who had received coffee for > 2
months...The effects of postnatal coffee ingestion in Guatemala were seen for sleep duration... Prenatal
coffee ingestion was negatively associated with Behavior Rating Scales.” (Engle P L, and others).
“From 602 Western New York undergraduate students in the spring of 2006...Frequency of energy
drink consumption was positively associated with marijuana use, sexual risk-taking, fighting, seatbelt
omission, and taking risks on a dare for the sample as a whole, and associated with smoking, drinking,
alcohol problems, and illicit prescription drug use for white students but not for black students... Energy
drink consumption is closely associated with a problem behavior syndrome, particularly among
whites. Frequent consumption of energy drinks may serve as a useful screening indicator to identify
students at risk for substance use and/or other health-compromising behavior.” (Miller K E).
XVI - 25) Behavioral disturbs at the second generation: “Intrauterine exposure to soft drinks rather
than coffee, the traditional focus, is associated with maternal reports of overactive behaviour in children
aged 18 months.” (Bekkhus M, and others).
“In utero exposure to caffeine and its metabolites results in altered behavioral patterns in infant monkeys.”
(Gilbert S G, and Rice D C).
On pregnant mice, “Perinatal caffeine, by acting on adenosine A(1) receptors in the mother, causes
long-lasting behavioral changes in the offspring that even manifest themselves in the second generation.”
(Björklund O, and others).
XVI - 26) Bipolar disorder. “Patients with bipolar disorder are at risk for an exacerbation of manic
symptoms when they consume large amounts of caffeine. This is due both to its direct psychostimulant
properties and secondary to increase renal excretion of lithium.” (Lande R G).
XVI - 27) Birth defects: Anotia/Microtia, Esophageal atresia, Small intestinal atresia, and
Craniosynostosis. “Using data from the National Birth Defects Prevention Study,...included 3,346 case
infants... born from October 1997 through December 2005. We observed small, statistically significant
elevations in adjusted odds ratios ranging from 1.3 to 1.8 for total maternal dietary caffeine intake or
specific types of caffeinated beverages and anotia/microtia, esophageal atresia, small intestinal atresia,
and craniosynostosis; however, dose-response patterns were absent.” (Browne M L, and others).
XVI - 28) Bladder cancer: In Uruguay, “In the time period 1996-2000, 255 incident cases with transitional
cell carcinoma of the bladder…Ever maté drinking was positively associated with bladder
cancer (odds ratio [OR] 2.2) and the risk increased for increasing duration and amount of maté drinking.
Both coffee and tea were strongly associated with bladder cancer risk (OR for coffee drinking 1.6;
OR for tea drinking 2.3). These results were confirmed in a separate analysis of never-smokers.” (De
Stefani E, and others).
Studying Netherlanders with 55 to 69 year-old, “The data suggest a possible positive association
between coffee consumption and bladder cancer risk in men and a probable inverse association in
women. Tea consumption was inversely associated with bladder cancer. Total fluid consumption
did not appear to be associated with bladder cancer.” (Zeegers M P, and others).
“In a cohort of Japanese, comprising a total of 49 566 men aged 40-69 years... coffee and caffeine
consumption were associated with an increased risk of bladder cancer in never- or former-smoking
men, with hazard ratios of coffee (one or more cups per day) and caffeine consumption of 2.24 and
2.05, respectively.” (Kurahashi N, and others).