Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

Fluids Hypertension Syndromes – Dr. Leonardo Izecksohn – page 255
“Tea and coffee contain catechins and flavonoids, which have been shown to exhibit anticarcinogenic
properties. Conversely, caffeine may elevate cancer risk through a variety of mechanisms. The current
study investigated the effects of regular consumption of black tea and coffee on lung cancer risk
among 993 current and former smokers with primary incident lung cancer (at Buffalo, NY 14263,
USA).…Lung cancer risk was not different for those with the highest black tea consumption (>or=2
cups/day) compared with nondrinkers of tea...However, elevated lung cancer risk was observed for participants
who consumed 2-3 cups of regular coffee daily (OR=1.34) or >or=4 cups of regular coffee
daily (OR=1.51). In contrast, decaffeinated coffee drinking was associated with decreased lung
cancer risk for both participants who consumed or=2 cups/day (OR=0.64). These results suggest that any chemoprotective effects of phytochemicals
in coffee and tea may be overshadowed by the elevated risk associated with caffeine in these beverages.”
(Baker J A, and others).
“The long-term intake of the dietary supplement [FastOne, which contains extracts of kola nut (with
caffeine and theobromine – Microsoft Bookshelf 98), grape, green tea (also with caffeine and theobromine)
and Ginkgo biloba, and is used as an agent for weight management] inducing CYP1A2 may
increase the incidence of colorectal cancers caused by procarcinogens activated by CYP1A2 in rapid
N-acetyltransferase-2 acetylators and of lung adenocarcinoma in slow acetylators.” (Ryu S D, and
Chung W G).
“Women with slow N-acetyltransferase 2 (NAT2) and rapid cytochrome P450 1A2 (CYP1A2) activity
were at highest risk relative to women with rapid NAT2 and slow Cytochrome P4501A2 activity, for
lung adenocarcinoma.” (Seow A, and others).
“Using a cell line derived from a human Pulmonary adenocarcinoma with Clara cell features and
immortalized human small airway epithelial cells, our data show that caffeine activated protein kinase
A (PKA), the mitogen-activated kinases ERK1/2, the nuclear transcription factor cyclic AMP response
element binding protein (CREB) and stimulated cell proliferation in these cell lines. These findings
suggest that exposure to caffeine may contribute to the prevalence of Pulmonary adenocarcinoma observed
today.” (Al-Wadei H A, and others).
XVI - 136) Lupus erythematosus: We observed on our patients who reduced their caffeine intake, that
those who were suffering with Lupus erythematosus and other autoimmune diseases became better
from them. We observed that their complaints reduced and their medications also could be reduced or
finished after finishing the caffeine intake. The incurable Lupus erythematosus maybe can be cured. We
think that the caffeine stimulates the production of auto-antibodies in the susceptible patient.
XVI - 137) Lymphatic edemas: They are chronic edemas caused by the increased production of
lymph in any place without the adequate drainage for that volume at that place. So, the lymph accumulates
and results in an edema. We had patients with many years of lymphatic edemas who where incurable
by any medicine, but became better or cured stopping the drinks of caffeine, wine and beer. As the
deficient drainage remained the same, our conclusion is that the etiologies of caffeine, wine and beer
where increasing the lymph production. Removing these etiologies, the lymph production reduced to
the physiologic, the lymphatic drainage became sufficient and those “incurable” lymphatic edemas
cured, without any medication or treatment.
XVI - 138) Malignant hyperthermia susceptibility: “Intramuscular caffeine injection leads to a significantly
higher increase of local lactate levels in malignant hyperthermia susceptible than in malignant
hyperthermia nonsusceptible and control individuals.” (Metterlein T, and others).
XVI - 139) Medullary disturbs: “On the medulla caffeine is a stimulant. The spinal cord reflexes are
also rendered more responsive. Muscular endurance is increased by moderate amounts; large doses, on
the other hand, occasion muscular trembling and weakness. In moderate amounts coffee possesses
some aphrodisiac action. Excessive doses lessen the activity of the spinal reflex centers.” (Butler G F).