Fluids Hypertension Syndromes: Migraines, Headaches, Normal ...

Fluids Hypertension Syndromes – Dr. Leonardo Izecksohn – page 268
- “As a competitive adenosine antagonist, caffeine affects dopamine transmission and has been reported
to worsen psychosis in people with schizophrenia and to cause psychosis in otherwise healthy
people. We report of case of apparent chronic caffeine-induced psychosis characterized by delusions
and paranoia in a 47-year-old man with high caffeine intake. The psychosis resolved within 7 weeks
after lowering caffeine intake without use of antipsychotic medication.” (Hedges D W, and others).
XVI - 193) Pterygium aggressiveness. We observed that the redness, swelling and invasive character
of the Pterygium and Pinguecula are consequent to the drinks of wine, beer, excessive water and caffeine,
besides other etiologies, as excessive solar radiation (ultraviolet light) and Vitamin A deficiency.
But we found the Pterygium ever together the Ocular or the Cerebrospinal Fluids Hypertension.
There are many years that we do not surgically excise any Pterygium, because medicating the patient
with 1 month of vitamin “A”, 50,000 units per day, totalizing 30 tablets, and withdrawing his beer,
wine, excessive water and caffeine, his Pterygium clarifies, wither and loose its aggressiveness. The
surgery is useless to the patient that stop his drinks.
Pterygium aggressiveness caused by caffeine and beer: We had a 57-year-old white woman, bonds
seller of a farm-hotel, two children. She used to drink more than 1,000 milliliter (around two pints) of
coffee and more than 3,000 milliliter of water (nearly one gallon) daily, and on weekends she drank
around 1,000 milliliter (three small cans) of beer daily. Years ago, she felt strong migraines. From four
years until now, she only complains of photophobia and chronic eyes redness. On ophthalmologic examination,
her intraocular pressures were 14 and 15 mmHg right and left eyes, normal. Her Optic
Nerve’s disks are physiologic. She is presenting medium size Pterygium in her both eyes, consequent to
excessive caffeine, water, beer and the sun her eyes receive on her working environment. We prescribed
her to stop the caffeine and beer drinks.
After 6 months she came again, and on this time her Pterygium were flat and whitish, no more bothering
her. There were no more photophobia or eyes redness.
XVI - 194) Rambling flow of thought and speech: It is caused by the caffeine intoxication, besides
many other etiologies.
XVI - 195) Raynaud's syndrome: “Raynaud's syndrome is classified into two groups: vasospastic or
obstructive. Vasospastic Raynaud's is generally cold-induced. Nicotine, stress, and caffeine are associated
with vasospasm.” (Whitaker L, and Kelleher A).
XVI - 196) Renal failure exacerbation in diabetic rats: “Caffeine produced a very mild increase (4
to 5%) of mean arterial blood pressure and heart rate, but greatly augmented proteinuria, reduced creatinine
clearance and had a mixed effect on metabolic status in obese ZSF1 rats. Caffeine significantly
reduced body weight, glycosuria, fasting glucose and insulin levels and improved glucose tolerance,
had no effect on elevated plasma triglycerides levels and significantly increased plasma cholesterol
level. Acute measurements of renal function revealed increased renal vascular resistance (95.1 +/- 11
vs. 50.7 +/- 2.4 mmHg/ml/min/g kidney) and decreased inulin clearance (0.37 +/- 0.11 vs. 0.97 +/- 0.13
ml/min/g kidney) in caffeine-treated animals. Caffeine potentiated the development of more severe tubulointerstitial
changes and increased focal glomerulosclerosis.” (Tofovic S P, and others).
XVI - 197) Renal papillary necrosis. Analgesic nephropathy:
“Case-control studies have shown that caffeine-containing analgesics are associated with analgesic
nephropathy”. (Zhang W Y).
“During the last decade the nephrotoxic potential of nonphenacetin-containing preparations has become
apparent. It is clear that people who abuse analgesics prefer combination analgesics containing 2
analgesics combined with caffeine and/or codeine.” “Effective prevention of analgesic nephropathy
consists of the prohibition of over-the-counter sales of preparation containing at least 2 analgesics associated
with caffeine and/or codeine.” (Elseviers M M, and De Broe M E.).