Clinician's Pocket Drug Reference 2008

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xMeredith B. Toma, PharmDClinical Assistant ProfessorClinical Pharmacy Specialist-Bloodand Marrow TransplantationUniversity of Oklahoma College ofPharmacyOklahoma City, OklahomaContributorsWilliam R. Vincent III,PharmDPostgraduate Year Two Critical CarePharmacy ResidentUniversity of Kentucky HealthCareLexington, Kentucky
PREFACEWe are pleased to present the 7th edition of the Clinician’s Pocket Drug Reference.This book is based on the drug presentation style used since 1983 in the Clinician’sPocket Reference, popularly known as the Scut Monkey Book. Our goal is to identifythe most frequently used and clinically important medications, includingbranded, generic and OTC products. The book includes well over 1000 medicationsand is designed to represent a cross section of commonly used products inmedical practices across the country.Our style of drug presentation includes key “must-know” facts of commonlyused medications, essential for both the student and practicing physician. The inclusionof common uses of medications rather than just the official FDA-labeledindications are based on the uses of the medication supported by publications andcommunity standards of care. All uses have been reviewed by our editorial board.It is essential that students and residents in training learn more than the nameand dose of the medications they prescribe. Certain common side effects and significantwarnings and contraindications are associated with prescription medications.Although health-care providers should ideally be completely familiar withthe entire package insert of any medication prescribed, such a requirement is unreasonable.References such as the Physician’s Desk Reference and the drug manufacturer’sWeb site make package inserts readily available for many medications,but may not highlight clinically significant facts or key data for generic drugs andthose available over the counter.The limitations of difficult-to-read package inserts were acknowledged by theFood and Drug Administration in early 2001, when it noted that physicians do nothave time to read the many pages of small print in the typical package insert.Newer drugs are producing more user-friendly package insert summaries that willhighlight important drug information for easier practitioner reference. Althoughuseful, these summaries do not commingle with similarly approved generic or“competing” similar products.The editorial board has analyzed the information on both brand and genericmedications and has made this key prescribing information available in thispocket-sized book. Information in this book is meant for use by health-care professionalswho are familiar with these commonly prescribed medications.This 2008 edition has been completely reviewed and updated by our editorialboard and technical contributors. Over 55 new drugs have been added, and changesin other medications based on FDA actions have been incorporated, including dele-xiCopyright © 2008 by Leonard G. Gomella. Click here for terms of use.
Page 2 and 3: CLINICIAN’S POCKETDRUG REFERENCE2
Page 4 and 5: ProfessionalWant to learn more?We h
Page 7 and 8: EDITORSLeonard G. Gomella, MD, FACS
Page 9 and 10: CONSULTING EDITORSVincenzo Berghell
Page 11: CONTRIBUTORSAmanda M. Ball, PharmDM
Page 15 and 16: MEDICATION KEYMedications are liste
Page 17 and 18: Medication KeyxvCategory ?: No data
Page 19 and 20: ABBREVIATIONS√: check or monitorA
Page 21 and 22: AbbreviationsInf: infusionInfxn: in
Page 23 and 24: AbbreviationsURI: upper respiratory
Page 25 and 26: CLASSIFICATION (Generic and common
Page 27 and 28: Last Classification 3PENICILLINSAmo
Page 29 and 30: Classification 5ANTINEOPLASTIC AGEN
Page 31 and 32: Classification 7Angiotensin-Convert
Page 33 and 34: Classification 9VasodilatorsAlprost
Page 35 and 36: Last Classification 11Miscellaneous
Page 37 and 38: Classification 13Miglitol (Glyset)N
Page 39 and 40: Classification 15Tobramycin, Ophtha
Page 41 and 42: Classification 17Infliximab (Remica
Page 43 and 44: Classification 19Hepatitis B Vaccin
Page 45 and 46: Classification 21Miscellaneous Ob/G
Page 47 and 48: Classification 23Guaifenesin (Robit
Page 49 and 50: Classification 25Orlistat (Xenical,
Page 51 and 52: GENERIC AND SELECTEDBRAND DRUG DATA
Page 53 and 54: Acyclovir 29Acetazolamide (Diamox)
Page 55 and 56: Alendronate 31PRN; 1 Rotacap inhale
Page 57 and 58: Alprostadil, Intracavernosal 33somn
Page 59 and 60: Amikacin 35Aluminum Hydroxide + Mag
Page 61 and 62: Ammonium Aluminum Sulfate 37tiarrhy
Page 63 and 64:
Amprenavir 39membrane sterols, alte
Page 65 and 66:
Argatroban 41Antithymocyte Globulin
Page 67 and 68:
Atomoxetine 43Aspirin + Butalbital,
Page 69 and 70:
Azithromycin 45Atropine, ophthalmic
Page 71 and 72:
Beclomethasone 47mg PO tid; ↑ q3d
Page 73 and 74:
Bismuth subcitrate/metroindazole/te
Page 75 and 76:
Budesonide/formoterol 51q3mo; max 2
Page 77 and 78:
Calcium Salts 531-4 mg IM or IV q3-
Page 79 and 80:
Carteolol 55mg/5 mL SE: Drowsiness,
Page 81 and 82:
Cefoperazone 57lergy Disp: Inj: 500
Page 83 and 84:
Celecoxib 59IV/im q8-12h. Peds. 30-
Page 85 and 86:
Chlorothiazide 61dairy Contra: Not
Page 87 and 88:
Cimetidine 63pseudomembranous colit
Page 89 and 90:
Clindamycin 65glove”-type neuropa
Page 91 and 92:
Clozapine 67Clopidogrel (Plavix) Us
Page 93 and 94:
Cyanocobalamin 69dysfunction Contra
Page 95 and 96:
Cytarabine 71phosphoramide mustard,
Page 97 and 98:
Dapsone, topical 730.5 mg/d for 5 d
Page 99 and 100:
Deferasirox 75300 mg SE: ↑ glucos
Page 101 and 102:
Diazepam 77Dexamethasone, Ophthalmi
Page 103 and 104:
Digoxin 79250-500 mg qid Peds 6 mo
Page 105 and 106:
Diphtheria, Tetanus Toxoids 81Dinop
Page 107 and 108:
Dolasetron 83Peds. Cont IV inf of 2
Page 109 and 110:
Droperidol 85Doxepin, Topical (Zona
Page 111 and 112:
Efavirenz, emtricitabine, tenofovir
Page 113 and 114:
Epinephrine 89Action: LMW heparin;
Page 115 and 116:
Erythromycin 91sis fluids, anticoag
Page 117 and 118:
Esterified Estrogens + Methyltestos
Page 119 and 120:
Estrogen, Conjugated 95on product;
Page 121 and 122:
Ethinyl Estradiol & Norelgestromin
Page 123 and 124:
Famciclovir 99plant subdermally q3y
Page 125 and 126:
Ferrous Gluconate 101Fentanyl ionto
Page 127 and 128:
Fludrocortisone Acetate 103seen in
Page 129 and 130:
Fluticasone, Nasal 105Fluoxetine (P
Page 131 and 132:
Fosfomycin 107DVT or PE in combo w/
Page 133 and 134:
Gemfibrozil 109Galantamine (Razadyn
Page 135 and 136:
Glyburide 111Susp, ophth: Prednisol
Page 137 and 138:
Heparin 11350-100 mg (2.5-5 mL) PO
Page 139 and 140:
Hydrocodone & Acetaminophen 115pher
Page 141 and 142:
Hydroxyzine 117Hydrocortisone, Rect
Page 143 and 144:
Imipenem-Cilastatin 119may repeat X
Page 145 and 146:
Influenza Vaccine 121[D, ?] ↑ eff
Page 147 and 148:
Interferon beta 1a 123Alfa-2b (Intr
Page 149 and 150:
Isosorbide Dinitrate 125Iron Dextra
Page 151 and 152:
Labetalol 127matophytes & yeast; sh
Page 153 and 154:
Letrozole 129H. pylori Infxn, erosi
Page 155 and 156:
Levonorgestrel IUD 131Disp: Multido
Page 157 and 158:
Lisinopril 133Adults. EMLA cream, a
Page 159 and 160:
Lutropin Alfa 1351st-gen against gr
Page 161 and 162:
Medroxyprogesterone 137over 5-60 mi
Page 163 and 164:
Mesalamine 139tigue, arthralgia, Gu
Page 165 and 166:
Methotrexate 141Contra: SCr > 1.4 i
Page 167 and 168:
Metronidazole 1436-12 yrs* Action:
Page 169 and 170:
Mirtazapine 145intrauterine pregnan
Page 171 and 172:
Moxifloxacin 147D 2nd & 3rd tri), ?
Page 173 and 174:
Naltrexone 149Caution: [C,?/- ] Eld
Page 175 and 176:
Neomycin & Polymyxin B 151Nefazodon
Page 177 and 178:
Nicotine Gum 153surgery Contra: NSA
Page 179 and 180:
Norepinephrine 155Nitrofurantoin (M
Page 181 and 182:
Omega-3 fatty acid 157dostatin LAR
Page 183 and 184:
Orphenadrine 159Disp: 28-d cycle pi
Page 185 and 186:
Oxycodone & Acetaminophen 161membra
Page 187 and 188:
Pamidronate 163Paclitaxel (Taxol, A
Page 189 and 190:
Pemetrexed 165constipation Notes: C
Page 191 and 192:
Pentobarbital 167synth. Spectrum: P
Page 193 and 194:
Phenylephrin, oral 169mia, constipa
Page 195 and 196:
Pirbuterol 171Pimecrolimus (Elidel)
Page 197 and 198:
Potassium Supplements 173Contra: GI
Page 199 and 200:
Procarbazine 175transmission modula
Page 201 and 202:
Protamine 177erides w/ extended dos
Page 203 and 204:
Ranibizumab 179Dose: 10-80 mg PO da
Page 205 and 206:
Rifaximin 181each dose (ECC 2005) C
Page 207 and 208:
Ropinirole 183or ergot alkaloids du
Page 209 and 210:
Selenium Sulfide 185chemo/RT Disp:
Page 211 and 212:
Sitagliptin 187Silver Nitrate (Dey-
Page 213 and 214:
Sorafenib 189izer Dose: Adults. 2-6
Page 215 and 216:
Steroids, Systemic 191Stavudine (Ze
Page 217 and 218:
Sulfacetamide 193mg/mL (1-g vial) S
Page 219 and 220:
Tamoxifen 195Sunitinib (Sutent) Use
Page 221 and 222:
Tenecteplase 197Telmisartan (Micard
Page 223 and 224:
Tetracycline 199Terconazole (Terazo
Page 225 and 226:
Ticarcillin/Potassium Clavulante 20
Page 227 and 228:
Tobramycin & Dexamethasone Ophthalm
Page 229 and 230:
Trandolapril 205Topiramate (Topamax
Page 231 and 232:
Trifluridine Ophthalmic 207& oint 1
Page 233 and 234:
Valproic Acid 209Triptorelin (Trels
Page 235 and 236:
Vinblastine 211Vasopressin [Antidiu
Page 237 and 238:
Ziconotide 213Warfarin (Coumadin) U
Page 239 and 240:
Zoster vaccine, live 215Initial 2.5
Page 241 and 242:
NATURAL and HERBAL AGENTSThe follow
Page 243 and 244:
Melatonin 219tablets or capsules or
Page 245 and 246:
Unsafe Herbs with Known Toxicity 22
Page 247 and 248:
Tables223Copyright © 2008 by Leona
Page 249 and 250:
6-8 y/48-59 lb/ 4 tab 2 tsp 2 cap/t
Page 251 and 252:
Tables 227TABLE 3Comparison of Syst
Page 253 and 254:
229Fluocinolone acetonide 0.2% Syna
Page 255 and 256:
Tables 231TABLE 5Comparison of Insu
Page 257 and 258:
233Lo/Ovral 21, 28 (Wyeth) Ethinyl
Page 259 and 260:
Tri-Sprintec (Barr) Ethinyl estradi
Page 261 and 262:
Tables 237TABLE 8Tetanus Prophylaxi
Page 263 and 264:
Tables 239TABLE 10Antiarrhythmics:
Page 265 and 266:
Tables 241TABLE 11 (continued)Cytoc
Page 267 and 268:
TABLE 13Composition of selected mul
Page 269 and 270:
Therapeutic 100 100 200 NA 150 200
Page 271 and 272:
Therapeutic 4 3 25 50 100 100 100
Page 273 and 274:
IndexAbacavir (Ziagen), 4, 27Abatac
Page 275 and 276:
Index 251Altabax (retapamulin), 4,
Page 277 and 278:
Index 253Atenolol and chlorthalidon
Page 279 and 280:
Index 255Bupropion (Wellbutrin, Zyb
Page 281 and 282:
Index 257Citalopram (Celexa), 10, 6
Page 283 and 284:
Index 259Dacarbazine (DTIC), 6, 72D
Page 285 and 286:
Index 261Dobutamine (Dobutrex), 8,
Page 287 and 288:
Index 263Estinyl (ethinyl estradiol
Page 289 and 290:
Index 265Flutamide (Eulexin), 5, 10
Page 291 and 292:
Index 267Human papillomavirus (type
Page 293 and 294:
Index 269Ipecac syrup, 1, 124Ipratr
Page 295 and 296:
Index 271Lithobid (lithium carbonat
Page 297 and 298:
Index 273Microgestin Fe, 233tMicro-
Page 299 and 300:
Index 275NeOral (cyclosporine), 71N
Page 301 and 302:
Index 277Oxacillin (Bactocill, Pros
Page 303 and 304:
Index 279Pneumococcal vaccine, poly
Page 305 and 306:
Index 281Quixin and Iquix ophthalmi
Page 307 and 308:
Index 283Serevent (salmeterol), 23S
Page 309 and 310:
Index 285Telmisartan (Micardis), 7,
Page 311 and 312:
Index 287Tri-Sprintec, 235tTrivora,
Page 313 and 314:
Index 289Yasmin, 234tYaz, 235tYohim
Page 315:
TIPS FOR SAFE PRESCRIPTION WRITING*
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