Clinician's Pocket Drug Reference 2008

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108 FosinoprilFosinopril (Monopril) Uses: *HTN, CHF,* DN Action: ACE inhibitorDose: 10 mg/d PO initial; max 40 mg/d PO; ↓ in elderly; ↓ in renal impair Caution:[D, +] ↑ K + w/ K + supls, ARBs, K + sparing diuretics; ↑ renal AE w/ NSAIDs,diuretics, hypovolemia Contra: Hereditary/idiopathic angioedema or angiodemaw/ ACE inhibitor, bilateral RAS Disp: Tabs 10, 20, 40 mg SE: Cough, dizziness,angioedema, ↑ K +Fosphenytoin (Cerebyx) Uses: *Status epilepticus* Action: ↓ Sz spreadin motor cortex Dose: As phenytoin equivalents (PE). Load: 15–20 mg PE/kg.Maint: 4–6 mg PE/kg/d; ↓ dosage, monitor levels in hepatic impair Caution: [D, +]May ↑ phenobarbital Contra: Sinus bradycardia, SA block, 2nd-/3rd-degree AVblock, Adams–Stokes synd, rash during Rx Disp: Inj 75 mg/mL SE: ↓ BP, dizziness,ataxia, pruritus, nystagmus Notes: 15 min to convert fosphenytoin to phenytoin;admin < 150 mg PE/min to prevent ↓ BP; administer with BP monitoringFrovatriptan (Frova) Uses: *Rx acute migraine* Action: Vascular serotoninreceptor agonist Dose: 2.5 mg PO repeat in 2 h PRN, 7.5 mg/d max PO dose;max 7.5 mg/d Caution: [C, ?/–] Contra: Angina, ischemic heart Dz, coronaryartery vasospasm, hemiplegic or basilar migraine, uncontrolled HTN, ergot use,MAOI use w/in 14 d Supplied: Tabs 2.5 mg SE: N, V, dizziness, hot flashes,paresthesias, dyspepsia, dry mouth, hot/cold sensation, chest pain, skeletal pain,flushing, weakness, numbness, coronary vasospasm, HTNFulvestrant (Faslodex) Uses: *HR(+) met breast CA in postmenopausalwomen w/ progression following antiestrogen therapy* Action: Estrogen receptorantagonist Dose: 250 mg IM monthly, as single 5-mL inj or two concurrent 2.5-mLIM inj in buttocks Caution: [X, ?/–] ↑ effects w/ CYP3A4 inhibitors (Table 11);w/ hepatic impair Contra: PRG Disp: Prefilled syringes 50 mg/mL (single 5 mL,dual 2.5 mL) SE: N/V/D, constipation, abd pain, HA, back pain, hot flushes,pharyngitis, inj site Rxns Notes: Only use IMFurosemide (Lasix) Uses: *CHF, HTN, edema,* ascites Action: Loop diuretic;↓ Na & Cl reabsorption in ascending loop of Henle & distal tubule Dose:Adults 20–80 mg PO or IV bid. Peds. 1 mg/kg/dose IV q6–12h; 2 mg/kg/dose POq12–24h (max 6 mg/kg/dose) Caution: [C, +] ↓ K+, ↑ risk of digoxin tox; ↑ riskof ototox w/ aminoglycosides, cisplatin (esp in renal dysfunction) Contra: Allergyto sulfonylureas; anuria; hepatic coma; electrolyte depletion Disp: Tabs 20, 40, 80mg; soln 10 mg/mL, 40 mg/5 mL; inj 10 mg/mL SE: ↓ BP, hyperglycemia, ↓ K +Notes: lytes, renal Fxn; high doses IV may cause ototoxGabapentin (Neurontin) Uses: Adjunct in *partial Szs; postherpeticneuralgia (PHN)*; chronic pain synds Action: Anticonvulsant Dose: Anticonvulsant:300–1200 mg PO tid (max 3600 mg/d). PHN: 300 mg day 1, 300 mg bidday 2, 300 mg tid day 3, titrate (1800–3600 mg/d); ↓ in renal impair Caution:[C, ?] Contra: Component sensitivity Disp: Caps 100, 300, 400, soln 250 mg/5mL; tab 600, 800 mg SE: Somnolence, dizziness, ataxia, fatigue Notes: Not necessaryto monitor levels
Gemfibrozil 109Galantamine (Razadyne) Uses: *Alzheimer Dz* Action: Acetylcholinesteraseinhibitor Dose: 4 mg PO bid, ↑ to 8 mg bid after 4 wk; may ↑ to 12mg bid in 4 wk Caution: [B, ?] ↑ effect w/ succinylcholine, amiodarone, diltiazem,verapamil, NSAIDs, digoxin; ↓ effect w/ anticholinergics, ? ↑ risk of deathvs placebo Contra: Severe renal/hepatic impair Disp: Tabs 4, 8, 12 mg; soln4 mg/mL SE: GI disturbances, wgt loss, sleep disturbances, dizziness, HA Notes:Caution w/ urinary outflow obst, Parkinson Dz, severe asthma/COPD, severe heartDz or ↓ BPGallium Nitrate (Ganite) Uses: *↑ Ca 2+ of malignancy*; bladder CAAction: ↓ bone resorption of Ca 2+ Dose: ↑ Ca 2+ : 200 mg/m 2 /day × 5 d. CA: 350mg/m 2 cont inf × 5 d to 700 mg/m 2 rapid IV inf q2wk in antineoplastic settings (perprotocols) Caution: [C, ?] Do not give w/ live or rotavirus vaccine Contra: SCr >2.5 mg/dL Disp: Inj 25 mg/mL SE: Renal insuff, ↓ Ca 2+ , hypophosphatemia, ↓ bicarb,
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CLINICIAN’S POCKETDRUG REFERENCE2
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ProfessionalWant to learn more?We h
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EDITORSLeonard G. Gomella, MD, FACS
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CONSULTING EDITORSVincenzo Berghell
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CONTRIBUTORSAmanda M. Ball, PharmDM
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PREFACEWe are pleased to present th
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MEDICATION KEYMedications are liste
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Medication KeyxvCategory ?: No data
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ABBREVIATIONS√: check or monitorA
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AbbreviationsInf: infusionInfxn: in
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AbbreviationsURI: upper respiratory
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CLASSIFICATION (Generic and common
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Last Classification 3PENICILLINSAmo
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Classification 5ANTINEOPLASTIC AGEN
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Classification 7Angiotensin-Convert
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Classification 9VasodilatorsAlprost
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Last Classification 11Miscellaneous
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Classification 13Miglitol (Glyset)N
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Classification 15Tobramycin, Ophtha
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Classification 17Infliximab (Remica
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Classification 19Hepatitis B Vaccin
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Classification 21Miscellaneous Ob/G
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Classification 23Guaifenesin (Robit
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Classification 25Orlistat (Xenical,
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GENERIC AND SELECTEDBRAND DRUG DATA
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Acyclovir 29Acetazolamide (Diamox)
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Alendronate 31PRN; 1 Rotacap inhale
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Alprostadil, Intracavernosal 33somn
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Amikacin 35Aluminum Hydroxide + Mag
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Ammonium Aluminum Sulfate 37tiarrhy
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Amprenavir 39membrane sterols, alte
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Argatroban 41Antithymocyte Globulin
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Atomoxetine 43Aspirin + Butalbital,
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Azithromycin 45Atropine, ophthalmic
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Beclomethasone 47mg PO tid; ↑ q3d
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Bismuth subcitrate/metroindazole/te
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Budesonide/formoterol 51q3mo; max 2
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Calcium Salts 531-4 mg IM or IV q3-
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Carteolol 55mg/5 mL SE: Drowsiness,
Page 81 and 82: Cefoperazone 57lergy Disp: Inj: 500
Page 83 and 84: Celecoxib 59IV/im q8-12h. Peds. 30-
Page 85 and 86: Chlorothiazide 61dairy Contra: Not
Page 87 and 88: Cimetidine 63pseudomembranous colit
Page 89 and 90: Clindamycin 65glove”-type neuropa
Page 91 and 92: Clozapine 67Clopidogrel (Plavix) Us
Page 93 and 94: Cyanocobalamin 69dysfunction Contra
Page 95 and 96: Cytarabine 71phosphoramide mustard,
Page 97 and 98: Dapsone, topical 730.5 mg/d for 5 d
Page 99 and 100: Deferasirox 75300 mg SE: ↑ glucos
Page 101 and 102: Diazepam 77Dexamethasone, Ophthalmi
Page 103 and 104: Digoxin 79250-500 mg qid Peds 6 mo
Page 105 and 106: Diphtheria, Tetanus Toxoids 81Dinop
Page 107 and 108: Dolasetron 83Peds. Cont IV inf of 2
Page 109 and 110: Droperidol 85Doxepin, Topical (Zona
Page 111 and 112: Efavirenz, emtricitabine, tenofovir
Page 113 and 114: Epinephrine 89Action: LMW heparin;
Page 115 and 116: Erythromycin 91sis fluids, anticoag
Page 117 and 118: Esterified Estrogens + Methyltestos
Page 119 and 120: Estrogen, Conjugated 95on product;
Page 121 and 122: Ethinyl Estradiol & Norelgestromin
Page 123 and 124: Famciclovir 99plant subdermally q3y
Page 125 and 126: Ferrous Gluconate 101Fentanyl ionto
Page 127 and 128: Fludrocortisone Acetate 103seen in
Page 129 and 130: Fluticasone, Nasal 105Fluoxetine (P
Page 131: Fosfomycin 107DVT or PE in combo w/
Page 135 and 136: Glyburide 111Susp, ophth: Prednisol
Page 137 and 138: Heparin 11350-100 mg (2.5-5 mL) PO
Page 139 and 140: Hydrocodone & Acetaminophen 115pher
Page 141 and 142: Hydroxyzine 117Hydrocortisone, Rect
Page 143 and 144: Imipenem-Cilastatin 119may repeat X
Page 145 and 146: Influenza Vaccine 121[D, ?] ↑ eff
Page 147 and 148: Interferon beta 1a 123Alfa-2b (Intr
Page 149 and 150: Isosorbide Dinitrate 125Iron Dextra
Page 151 and 152: Labetalol 127matophytes & yeast; sh
Page 153 and 154: Letrozole 129H. pylori Infxn, erosi
Page 155 and 156: Levonorgestrel IUD 131Disp: Multido
Page 157 and 158: Lisinopril 133Adults. EMLA cream, a
Page 159 and 160: Lutropin Alfa 1351st-gen against gr
Page 161 and 162: Medroxyprogesterone 137over 5-60 mi
Page 163 and 164: Mesalamine 139tigue, arthralgia, Gu
Page 165 and 166: Methotrexate 141Contra: SCr > 1.4 i
Page 167 and 168: Metronidazole 1436-12 yrs* Action:
Page 169 and 170: Mirtazapine 145intrauterine pregnan
Page 171 and 172: Moxifloxacin 147D 2nd & 3rd tri), ?
Page 173 and 174: Naltrexone 149Caution: [C,?/- ] Eld
Page 175 and 176: Neomycin & Polymyxin B 151Nefazodon
Page 177 and 178: Nicotine Gum 153surgery Contra: NSA
Page 179 and 180: Norepinephrine 155Nitrofurantoin (M
Page 181 and 182: Omega-3 fatty acid 157dostatin LAR
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Orphenadrine 159Disp: 28-d cycle pi
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Oxycodone & Acetaminophen 161membra
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Pamidronate 163Paclitaxel (Taxol, A
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Pemetrexed 165constipation Notes: C
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Pentobarbital 167synth. Spectrum: P
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Phenylephrin, oral 169mia, constipa
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Pirbuterol 171Pimecrolimus (Elidel)
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Potassium Supplements 173Contra: GI
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Procarbazine 175transmission modula
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Protamine 177erides w/ extended dos
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Ranibizumab 179Dose: 10-80 mg PO da
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Rifaximin 181each dose (ECC 2005) C
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Ropinirole 183or ergot alkaloids du
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Selenium Sulfide 185chemo/RT Disp:
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Sitagliptin 187Silver Nitrate (Dey-
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Sorafenib 189izer Dose: Adults. 2-6
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Steroids, Systemic 191Stavudine (Ze
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Sulfacetamide 193mg/mL (1-g vial) S
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Tamoxifen 195Sunitinib (Sutent) Use
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Tenecteplase 197Telmisartan (Micard
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Tetracycline 199Terconazole (Terazo
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Ticarcillin/Potassium Clavulante 20
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Tobramycin & Dexamethasone Ophthalm
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Trandolapril 205Topiramate (Topamax
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Trifluridine Ophthalmic 207& oint 1
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Valproic Acid 209Triptorelin (Trels
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Vinblastine 211Vasopressin [Antidiu
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Ziconotide 213Warfarin (Coumadin) U
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Zoster vaccine, live 215Initial 2.5
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NATURAL and HERBAL AGENTSThe follow
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Melatonin 219tablets or capsules or
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Unsafe Herbs with Known Toxicity 22
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Tables223Copyright © 2008 by Leona
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6-8 y/48-59 lb/ 4 tab 2 tsp 2 cap/t
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Tables 227TABLE 3Comparison of Syst
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229Fluocinolone acetonide 0.2% Syna
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Tables 231TABLE 5Comparison of Insu
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233Lo/Ovral 21, 28 (Wyeth) Ethinyl
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Tri-Sprintec (Barr) Ethinyl estradi
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Tables 237TABLE 8Tetanus Prophylaxi
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Tables 239TABLE 10Antiarrhythmics:
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Tables 241TABLE 11 (continued)Cytoc
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TABLE 13Composition of selected mul
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Therapeutic 100 100 200 NA 150 200
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Therapeutic 4 3 25 50 100 100 100
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IndexAbacavir (Ziagen), 4, 27Abatac
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Index 251Altabax (retapamulin), 4,
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Index 253Atenolol and chlorthalidon
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Index 255Bupropion (Wellbutrin, Zyb
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Index 257Citalopram (Celexa), 10, 6
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Index 259Dacarbazine (DTIC), 6, 72D
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Index 261Dobutamine (Dobutrex), 8,
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Index 263Estinyl (ethinyl estradiol
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Index 265Flutamide (Eulexin), 5, 10
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Index 267Human papillomavirus (type
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Index 269Ipecac syrup, 1, 124Ipratr
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Index 271Lithobid (lithium carbonat
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Index 273Microgestin Fe, 233tMicro-
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Index 275NeOral (cyclosporine), 71N
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Index 277Oxacillin (Bactocill, Pros
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Index 279Pneumococcal vaccine, poly
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Index 281Quixin and Iquix ophthalmi
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Index 283Serevent (salmeterol), 23S
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Index 285Telmisartan (Micardis), 7,
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Index 287Tri-Sprintec, 235tTrivora,
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Index 289Yasmin, 234tYaz, 235tYohim
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TIPS FOR SAFE PRESCRIPTION WRITING*
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