Clinician's Pocket Drug Reference 2008

Budesonide/formoterol 51q3mo; max 200 units/30 d cum dose; cervical dystonia 198–300 units IM divided12 y: see adult; cervical dystonia >16 y:198–300 units IM ÷ among affected muscles; use 12 y: 1.25–2.5 units IM/site q3mo; 25 units/site max; inject extraocularmuscles w/ EMG guidance Caution: [C, ?] w/neurologic Dz Contra: hypersensitivityto components, infect at inj site Disp: powder for reconst SE: Anaphylaxis, erythemamultiforme, dysphagia, dyspnea, syncope, HA, NAG, inj site painBrimonidine (Alphagan P) Uses: *Open-angle glaucoma, ocular HTN*Action: α 2 -Adrenergic agonist Dose: 1 gtt in eye(s) tid (wait 15 min to insert contacts)Caution: [B, ?] Contra: MAOI therapy Disp: 0.15, 0.1% soln SE: Local irritation,HA, fatigueBrinzolamide (Azopt) Uses: *Open-angle glaucoma, ocular HTN* Action:Carbonic anhydrase inhibitor Dose: 1 gtt in eye(s) tid Caution: [C, ?] Contra:Sulfonamide allergy Disp: 1% susp SE: Blurred vision, dry eye, blepharitis,taste disturbanceBromocriptine (Parlodel) Uses: *Parkinson Dz, hyperprolactinemia,acromegaly, pituitary tumors* Action: Direct-acting on the striatal dopamine receptors;↓ prolactin secretion Dose: Initial, 1.25 mg PO bid; titrate to effect,w/food Caution: [B, ?] Contra: Severe ischemic heart Dz or PVD Disp: Tabs 2.5mg; caps 5 mg SE: ↓ BP, Raynaud phenomenon, dizziness, N, hallucinationsBudesonide (Rhinocort Aqua, Pulmicort) Uses: *Allergic & nonallergicrhinitis, asthma* Action: Steroid Dose: Adults: Rhinocort Aqua 1–4sprays/nostril/d; Turbuhaler 1–4 inhal bid; Pulmicort Flexhaler 1–2 inhal bid Peds:Rhinocort Aqua intranasal 1–2 sprays/nostril/d; Pulmicort Turbuhaler 1–2 inhalbid, Respules: 0.25–0.5 mg daily or bid (Rinse mouth after PO use) Caution: [C,?/–] Disp: Met-dose Turbuhaler, 200 mcg/inhalation; Flexhaler 90, 180 mcg/inh,;Respules 0.25, 0.5 mg/2 mL; Rhinocort Aqua 32 mcg/spray SE: HA, cough,hoarseness, Candida Infxn, epistaxisBudesonide, oral (Entocort EC) Uses: *Mild-moderate Crohn Dz* Action:Steroid, anti-inflammatory Dose: Adults: initial, 9 mg PO qam to 8 wk max:maint 6 mg PO qam taper by 3 mo; avoid grapefruit juice Contra: Active TB andfungal Infxn Caution: [C, ?/–] DM, glaucoma, cataracts, HTN, CHF Disp: Caps 3mg ER SE: HA, cough, hoarseness, Candida Infxn, epistaxis Notes: Do notcut/crush/chewBudesonide/formoterol (Symbicort) WARNING: Long-acting B2agonists may ↑ risk of asthma-related death Uses: *Asthma maintenance * Action:Steroid w/LA beta-2-agonist Dose: Adult and Peds > 12 y.: 2 inhal BIDCaution: [C, ?] w/transfer from systemic to inhal steroids Contra: acute attackDisp: inhal 80/4.5, 160/4.5 SE: allergic rxns, HA, tremor, ↑ BP & HR, ↑ infectionrisk, throat irritation, growth ↓ in children