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Clinician's Pocket Drug Reference 2008

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Unsafe Herbs with Known Toxicity 221Unsafe Herbs with Known ToxicityAgentAconiteAristolochic acidCalamusChaparral“Chinese herbalmixtures”ColtsfootComfreyEphedra/MaHuangJuniperKava kavaLicoriceLife rootMaHuang/EphedraPokeweedSassafrasUsnic acidYohimbineToxicitiesSalivation, N/V, blurred vision, cardiac arrhythmiasNephrotoxPossible carcinogenicityHepatotox, possible carcinogenicity, nephrotoxMay contain MaHuang or other dangerous herbsHepatotox, possibly carcinogenicHepatotox, carcinogenicAdverse cardiac events, stroke, SzHigh allergy potential, D, Sz, nephrotoxHepatotoxChronic daily amounts (> 30 g/mo) can result in ↓K + , Na/fluid retention w/HTN, myoglobinuria,hyporeflexiaHepatotox, liver cancerAdverse cardiac events, stroke, SzGI cramping, N/D/V, labored breathing, ↓ BP, SzV, stupor, hallucinations, dermatitis, abortion,hypothermia, liver cancerHepatotoxHypotension, abdominal distress, CNS stimulation(mania/& psychosis in predisposed individuals)

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