Clinician's Pocket Drug Reference 2008

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40 AnakinraAnakinra (Kineret) WARNING: Associated w/ ↑ incidence of seriousInfxn; D/C w/ serious Infxn Uses: *Reduce signs & Sxs of moderate/severe activeRA, failed 1 or more DMARD* Action: Human IL-1 receptor antagonistDose: 100 mg SQ daily; w/CrCl
Argatroban 41Antithymocyte Globulin (See Lymphocyte Immune Globulin,page 136)Apomorphine (Apokyn) WARNING: Do not administer IV Uses:*Acute, intermittent hypomobility (“off”) episodes of Parkinson Dz* Action:Dopamine agonist Dose: Adults. 0.2-mL SQ test dose under medical supervision;if BP OK, initial 0.2 mL (2 mg) SQ during “off” periods; only 1 dose per “off” period;titrate dose; 0.6 mL (6 mg)max single doses; use w/antiemetic; ↓ in renal impairCaution: [C, +/–] Avoid EtOH; antihypertensives, vasodilators, cardio orcerebrovascular Dz, hepatic impair Contra: 5HT3 antagonists, sulfite allergyDisp: Inj 10 mg/mL, 3-mL pen cartridges; 2-mL amp SE: Emesis, syncope, QTprolongation, orthostatic ↓ BP, somnolence, ischemia, injection site Rxn, abuse potential,dyskinesia, fibrotic conditions, priapism Notes: Daytime somnolence maylimit activities; trimethobenzamide 300 mg tid PO or other non-5HT3 antagonistantiemetic given 3 d prior to & up to 2 mo following initiationApraclonidine (Iopidine) Uses: *Glaucoma, postop intraocular HTN*Action: α 2 -adrenergic agonist Dose: 1–2 gtt of 0.5% tid; 1 gtt before and after surgicalprocedure Caution: [C, ?] Contra: w/ MAOI Disp: 0.5, 1% soln SE: Ocularirritation, lethargy, xerostomiaAprepitant (Emend) Uses *Prevents N/V assoc w/ emetogenic CAchemo (eg, cisplatin) (use in combo w/ other antiemetics)* Action: SubstanceP/neurokinin 1(NK 1 ) receptor antagonist Dose: 125 mg PO day 1, 1 h beforechemo, then 80 mg PO q AM days 2 & 3 Caution: [B, ?/–]; substrate & modCYP3A4 inhibitor; CYP2C9 inducer (Table 11) Contra: Use w/ pimozide, Disp:Caps 40, 80, 125 mg SE: Fatigue, asthenia, hiccups Notes: ↓ effect OCP andwarfarinAprotinin (Trasylol) WARNING: May cause fatal anaphylactic Rxns Uses:*↓ loss during CABG* Action: Protease inhib, antifibrinolytic Dose: 1-mL IV testdose; High dose: 2 million KIU load, 2 million KIU to prime pump, then 500,000KIU/h until surgery ends; Low dose: 1 million KIU load, 1 million KIU to primepump, then 250,000 KIU/h until surgery ends; 7 million KIU max total Caution: [B,?] Thromboembolic Dz requiring anticoagulants/blood factor administration Contra:Previous use
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CLINICIAN’S POCKETDRUG REFERENCE2
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ProfessionalWant to learn more?We h
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EDITORSLeonard G. Gomella, MD, FACS
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CONSULTING EDITORSVincenzo Berghell
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CONTRIBUTORSAmanda M. Ball, PharmDM
Page 13 and 14: PREFACEWe are pleased to present th
Page 15 and 16: MEDICATION KEYMedications are liste
Page 17 and 18: Medication KeyxvCategory ?: No data
Page 19 and 20: ABBREVIATIONS√: check or monitorA
Page 21 and 22: AbbreviationsInf: infusionInfxn: in
Page 23 and 24: AbbreviationsURI: upper respiratory
Page 25 and 26: CLASSIFICATION (Generic and common
Page 27 and 28: Last Classification 3PENICILLINSAmo
Page 29 and 30: Classification 5ANTINEOPLASTIC AGEN
Page 31 and 32: Classification 7Angiotensin-Convert
Page 33 and 34: Classification 9VasodilatorsAlprost
Page 35 and 36: Last Classification 11Miscellaneous
Page 37 and 38: Classification 13Miglitol (Glyset)N
Page 39 and 40: Classification 15Tobramycin, Ophtha
Page 41 and 42: Classification 17Infliximab (Remica
Page 43 and 44: Classification 19Hepatitis B Vaccin
Page 45 and 46: Classification 21Miscellaneous Ob/G
Page 47 and 48: Classification 23Guaifenesin (Robit
Page 49 and 50: Classification 25Orlistat (Xenical,
Page 51 and 52: GENERIC AND SELECTEDBRAND DRUG DATA
Page 53 and 54: Acyclovir 29Acetazolamide (Diamox)
Page 55 and 56: Alendronate 31PRN; 1 Rotacap inhale
Page 57 and 58: Alprostadil, Intracavernosal 33somn
Page 59 and 60: Amikacin 35Aluminum Hydroxide + Mag
Page 61 and 62: Ammonium Aluminum Sulfate 37tiarrhy
Page 63: Amprenavir 39membrane sterols, alte
Page 67 and 68: Atomoxetine 43Aspirin + Butalbital,
Page 69 and 70: Azithromycin 45Atropine, ophthalmic
Page 71 and 72: Beclomethasone 47mg PO tid; ↑ q3d
Page 73 and 74: Bismuth subcitrate/metroindazole/te
Page 75 and 76: Budesonide/formoterol 51q3mo; max 2
Page 77 and 78: Calcium Salts 531-4 mg IM or IV q3-
Page 79 and 80: Carteolol 55mg/5 mL SE: Drowsiness,
Page 81 and 82: Cefoperazone 57lergy Disp: Inj: 500
Page 83 and 84: Celecoxib 59IV/im q8-12h. Peds. 30-
Page 85 and 86: Chlorothiazide 61dairy Contra: Not
Page 87 and 88: Cimetidine 63pseudomembranous colit
Page 89 and 90: Clindamycin 65glove”-type neuropa
Page 91 and 92: Clozapine 67Clopidogrel (Plavix) Us
Page 93 and 94: Cyanocobalamin 69dysfunction Contra
Page 95 and 96: Cytarabine 71phosphoramide mustard,
Page 97 and 98: Dapsone, topical 730.5 mg/d for 5 d
Page 99 and 100: Deferasirox 75300 mg SE: ↑ glucos
Page 101 and 102: Diazepam 77Dexamethasone, Ophthalmi
Page 103 and 104: Digoxin 79250-500 mg qid Peds 6 mo
Page 105 and 106: Diphtheria, Tetanus Toxoids 81Dinop
Page 107 and 108: Dolasetron 83Peds. Cont IV inf of 2
Page 109 and 110: Droperidol 85Doxepin, Topical (Zona
Page 111 and 112: Efavirenz, emtricitabine, tenofovir
Page 113 and 114: Epinephrine 89Action: LMW heparin;
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Erythromycin 91sis fluids, anticoag
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Esterified Estrogens + Methyltestos
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Estrogen, Conjugated 95on product;
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Ethinyl Estradiol & Norelgestromin
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Famciclovir 99plant subdermally q3y
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Ferrous Gluconate 101Fentanyl ionto
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Fludrocortisone Acetate 103seen in
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Fluticasone, Nasal 105Fluoxetine (P
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Fosfomycin 107DVT or PE in combo w/
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Gemfibrozil 109Galantamine (Razadyn
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Glyburide 111Susp, ophth: Prednisol
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Heparin 11350-100 mg (2.5-5 mL) PO
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Hydrocodone & Acetaminophen 115pher
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Hydroxyzine 117Hydrocortisone, Rect
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Imipenem-Cilastatin 119may repeat X
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Influenza Vaccine 121[D, ?] ↑ eff
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Interferon beta 1a 123Alfa-2b (Intr
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Isosorbide Dinitrate 125Iron Dextra
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Labetalol 127matophytes & yeast; sh
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Letrozole 129H. pylori Infxn, erosi
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Levonorgestrel IUD 131Disp: Multido
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Lisinopril 133Adults. EMLA cream, a
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Lutropin Alfa 1351st-gen against gr
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Medroxyprogesterone 137over 5-60 mi
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Mesalamine 139tigue, arthralgia, Gu
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Methotrexate 141Contra: SCr > 1.4 i
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Metronidazole 1436-12 yrs* Action:
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Mirtazapine 145intrauterine pregnan
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Moxifloxacin 147D 2nd & 3rd tri), ?
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Naltrexone 149Caution: [C,?/- ] Eld
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Neomycin & Polymyxin B 151Nefazodon
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Nicotine Gum 153surgery Contra: NSA
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Norepinephrine 155Nitrofurantoin (M
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Omega-3 fatty acid 157dostatin LAR
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Orphenadrine 159Disp: 28-d cycle pi
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Oxycodone & Acetaminophen 161membra
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Pamidronate 163Paclitaxel (Taxol, A
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Pemetrexed 165constipation Notes: C
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Pentobarbital 167synth. Spectrum: P
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Phenylephrin, oral 169mia, constipa
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Pirbuterol 171Pimecrolimus (Elidel)
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Potassium Supplements 173Contra: GI
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Procarbazine 175transmission modula
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Protamine 177erides w/ extended dos
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Ranibizumab 179Dose: 10-80 mg PO da
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Rifaximin 181each dose (ECC 2005) C
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Ropinirole 183or ergot alkaloids du
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Selenium Sulfide 185chemo/RT Disp:
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Sitagliptin 187Silver Nitrate (Dey-
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Sorafenib 189izer Dose: Adults. 2-6
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Steroids, Systemic 191Stavudine (Ze
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Sulfacetamide 193mg/mL (1-g vial) S
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Tamoxifen 195Sunitinib (Sutent) Use
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Tenecteplase 197Telmisartan (Micard
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Tetracycline 199Terconazole (Terazo
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Ticarcillin/Potassium Clavulante 20
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Tobramycin & Dexamethasone Ophthalm
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Trandolapril 205Topiramate (Topamax
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Trifluridine Ophthalmic 207& oint 1
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Valproic Acid 209Triptorelin (Trels
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Vinblastine 211Vasopressin [Antidiu
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Ziconotide 213Warfarin (Coumadin) U
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Zoster vaccine, live 215Initial 2.5
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NATURAL and HERBAL AGENTSThe follow
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Melatonin 219tablets or capsules or
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Unsafe Herbs with Known Toxicity 22
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Tables223Copyright © 2008 by Leona
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6-8 y/48-59 lb/ 4 tab 2 tsp 2 cap/t
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Tables 227TABLE 3Comparison of Syst
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229Fluocinolone acetonide 0.2% Syna
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Tables 231TABLE 5Comparison of Insu
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233Lo/Ovral 21, 28 (Wyeth) Ethinyl
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Tri-Sprintec (Barr) Ethinyl estradi
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Tables 237TABLE 8Tetanus Prophylaxi
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Tables 239TABLE 10Antiarrhythmics:
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Tables 241TABLE 11 (continued)Cytoc
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TABLE 13Composition of selected mul
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Therapeutic 100 100 200 NA 150 200
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Therapeutic 4 3 25 50 100 100 100
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IndexAbacavir (Ziagen), 4, 27Abatac
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Index 251Altabax (retapamulin), 4,
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Index 253Atenolol and chlorthalidon
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Index 255Bupropion (Wellbutrin, Zyb
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Index 257Citalopram (Celexa), 10, 6
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Index 259Dacarbazine (DTIC), 6, 72D
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Index 261Dobutamine (Dobutrex), 8,
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Index 263Estinyl (ethinyl estradiol
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Index 265Flutamide (Eulexin), 5, 10
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Index 267Human papillomavirus (type
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Index 269Ipecac syrup, 1, 124Ipratr
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Index 271Lithobid (lithium carbonat
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Index 273Microgestin Fe, 233tMicro-
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Index 275NeOral (cyclosporine), 71N
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Index 277Oxacillin (Bactocill, Pros
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Index 279Pneumococcal vaccine, poly
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Index 281Quixin and Iquix ophthalmi
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Index 283Serevent (salmeterol), 23S
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Index 285Telmisartan (Micardis), 7,
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Index 287Tri-Sprintec, 235tTrivora,
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Index 289Yasmin, 234tYaz, 235tYohim
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TIPS FOR SAFE PRESCRIPTION WRITING*
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