Clinician's Pocket Drug Reference 2008

Heparin 11350–100 mg (2.5–5 mL) PO q4h (max 600 mg/d). 6–11 y: 100–200 mg (5–10 mL)PO q4h (max 1.2 g/d) Caution: [C, ?] Disp: Tabs 100, 200; SR tabs 600, 1200 mg;caps 200 mg; SR caps 300 mg; liq 100 mg/5 mL SE: GI upset Notes Give w/ largeamount of H 2 O; some dosage forms contain EtOHGuaifenesin & Codeine (Robitussin AC, Brontex, others)[C-V] Uses: *Relief of dry cough* Action: Antitussive w/ expectorant Dose:Adults. 5–10 mL or 1 tab PO q6–8h (max 60 mL/24 h). Peds. 2–6 y: 1–1.5 mg/kgcodeine/d ÷ dose q4–6h (max 30 mg/24 h). 6–12 y: 5 mL q4h (max 30 mL/24 h)Caution: [C, +] Disp: Brontex tab 10 mg codeine/300 mg guaifenesin; liq 2.5 mgcodeine/75 mg guaifenesin/5 mL; others 10 mg codeine/100 mg guaifenesin/5 mLSE: SomnolenceGuaifenesin & Dextromethorphan (many OTC brands)Uses: *Cough* due to upper resp tract irritation Action: Antitussive w/ expectorantDose: Adults & Peds >12 y. 10 mL PO q6–8h (max 40 mL/24 h). Peds. 2–6 y:Dextromethorphan 1–2 mg/kg/24 h ÷ 3–4 × d (max 10 mL/d). 6–12 y: 5 mL q6–8h(max 20 mL/d) Caution: [C, +] Contra: Administration w/ MAOI Disp: ManyOTC formulations SE: Somnolence Notes: Give with plenty of fluidsHaemophilus B Conjugate Vaccine (ActHIB, HibTITER, PedvaxHIB,Prohibit, others) Uses: Routine *immunization* of childrenagainst H. influenzae type B Dzs Action: Active immunization againstHaemophilus B Dose: Peds. 0.5 mL (25 mg) IM in deltoid or vastus lateralis Caution:[C, +] Contra: Febrile illness, immunosuppression, allergy to thimerosalDisp: Inj 7.5, 10, 15, 25 mcg/0.5 mL SE: Observe for anaphylaxis; edema, ↑ riskof Haemophilus B Infxn the week after vaccination Notes: Booster not required;report SAE to VAERS: 1-800-822-7967Haloperidol (Haldol) Uses: *Psychotic disorders, agitation, Tourette disorders,hyperactivity in children* Action: Antipsychotic, neuroleptic Dose:Adults. Moderate Sxs: 0.5–2 mg PO bid–tid. Severe Sxs/agitation: 3–5 mg PObid–tid or 1–5 mg IM q4h PRN (max 100 mg/d). Peds. 3–6 y: 0.01–0.03 mg/kg/24 hPO daily. 6–12 y: Initial, 0.5–1.5 mg/24 h PO; ↑ by 0.5 mg/24 h to maintenance of2–4 mg/24 h (0.05–0.1 mg/kg/24 h) or 1–3 mg/dose IM q4–8h to 0.1 mg/kg/24 hmax; Tourette Dz may require up to 15 mg/24 h PO; ↓ in elderly Caution: [C, ?] ↑effects w/ SSRIs, CNS depressants, TCA, indomethacin, metoclopramide; avoidlevodopa (↓ antiparkinsonian effects) Contra: NAG, severe CNS depression,coma, Parkinson Dz, BM suppression, severe cardiac/hepatic Dz Disp: Tabs 0.5, 1,2, 5, 10, 20 mg; conc liq 2 mg/mL; inj 5 mg/mL; decanoate inj 50, 100 mg/mL SE:Extrapyramidal Sxs (EPS), ↓ BP, anxiety, dystonias Notes: Do not give decanoateIV; dilute PO conc liq w/ H 2 O/juice; monitor for EPSHeparin Uses: *Rx & prevention of DVT & PE,* unstable angina, AF w/ emboli,& acute arterial occlusion Action: Acts w/ antithrombin III to inactivatethrombin & ↓ thromboplastin formation Dose: Adults. Prophylaxis: 3000–5000units SQ q8–12h. Thrombosis Rx: Load 50–80 units/kg IV, then 10–20 units/kg IV