Clinician's Pocket Drug Reference 2008

238 TablesTABLE 9Oral Anticoagulant Standards of PracticeThromboembolic Disorder INR DurationDeep Venous Thrombosis & Pulmonary EmbolismTreatment single episodeTransient risk factor 2–3 3 moIdiopathic 2–3 6–12 moRecurrent systemic embolism 2–3 IndefinitePrevention of Systemic EmbolismAtrial fibrillation (AF) a 2–3 IndefiniteAF: cardioversion 2–3 3 wk prior;4 wk post sinus rhythmValvular heart disease 2–3 IndefiniteCardiomyopathy 2–3 IndefiniteAcute Myocardial InfarctionHigh risk patients c 2–3 + 3 molow doseaspirinProsthetic ValvesTissue heart valves 2–3 3 moBileaflet mechanical valves in 2–3 Indefiniteaortic positionOther mechanical prosthetic valves b 2.5–3.5 Indefinitea With high-risk factors or multiple moderate risk factors.b May add aspirin 81 mg to warfarin in patients with caged ball or caged disk valves or with additional riskfactors.c Large anterior MI, significant heart failure, intracardiac thrombus, and/or history of thromboembolic event.INR = international normalized ratio.Source: Based on data published in Chest 2004 Sep; 126 (Suppl): 1635–6965.